I-Sorafenib

Umxholo

• Ngaphambi kokuba uthathe i-sorafenib,
• I-Sorafenib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:
• Iimpawu libanda kungaquka oku kulandelayo:

I-Sorafenib isetyenziselwa ukunyanga i-renal cell carcinoma (RCC; uhlobo lomhlaza oqala kwizintso). I-Sorafenib ikwasetyenziselwa ukunyanga i-hepatocellular carcinoma (uhlobo lomhlaza wesibindi) ongenakunyangwa ngoqhaqho kunye nohlobo oluthile lomhlaza we-thyroid osasazeke kwamanye amalungu omzimba kwaye awunakunyangwa nge-iodine ene-radioactive. USorafenib ukwiklasi yamayeza abizwa ngokuba yi-kinase inhibitors. Isebenza ngokuthintela isenzo seprotein engaqhelekanga ebonisa iiseli zomhlaza ukuba zande. Oku kunceda ukunqanda ukusasazeka kweeseli zomhlaza.

I-Sorafenib iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kabini ngemini. I-Sorafenib ithathwa ngaphandle kokutya, iyure enye ngaphambi okanye iiyure ezi-2 emva kwesidlo. Thatha i-sorafenib ngeenxa zonke ngamaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-sorafenib ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya iipilisi ngamanzi. Musa ukwahlula, ukuhlafuna, okanye ukuchoboza.

Ugqirha wakho unokunciphisa idosi yakho ye-sorafenib ngexesha lonyango lwakho, okanye angakuxelela ukuba uyeke okwethutyana okanye ngokusisigxina uyeke ukuthatha i-sorafenib kangangexesha elithile ukuba uneziphumo ebezingalindelekanga. Qiniseka ukuba uxelela ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho nge-sorafenib.

Qhubeka nokuthatha i-sorafenib nokuba uziva uphilile. Sukuyeka ukuthatha i-sorafenib ungakhange uthethe nogqirha wakho.

I-Sorafenib ayifumaneki kwii-pharmacy. Unokufumana kuphela i-sorafenib ngeposi evela kwikhemesti ekhethekileyo. Buza ugqirha wakho ukuba unemibuzo malunga nokufumana amayeza akho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-sorafenib,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-sorafenib, nawaphi na amanye amayeza, okanye ezinye izithako kwiipilisi ze-sorafenib. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho ukuba unomdlavuza wamaphaphu kwaye ufumana unyango nge-carboplatin (Paraplatin) kunye ne-paclitaxel (Abraxane, Onxol, Taxol) okanye i-gemcitabine (Gemzar) kunye ne-cisplatin (Platinol). Ugqirha wakho uya kukuxelela ukuba ungathathi i-sorafenib ukuba unomdlavuza wemiphunga kwaye ufumana la mayeza.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhalwanga, iivithamini, kunye nezongezelelo zesondlo ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya oku kulandelayo: amayeza athile e-arrhythmias anje nge-amiodarone (Nexterone, Pacerone), dofetilide (Tikosyn), dronedarone (Multaq), procainamide, quinidine (eNuedexta), kunye ne-sotalol (iBetapace, iSorine, iSotylize); ii-anticoagulants (igazi elincinci) njenge-warfarin (Coumadin, Jantoven); carbamazepine (i-Equetro, iTegretol, iTeril); dexamethasone; ibutilide (iCorvert); irinotecan (Camptosar); neomycin; phenobarbital; phenytoin (iDilantin, iPhenytek); irifabutin (Mycobutin); okanye i-rifampin (iRifadin, iRimactane). Amanye amayeza amaninzi anokusebenzisana ne-sorafenib, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
• xelela ugqirha wakho ukuba ukhe waba noxinzelelo oluphezulu lwegazi, iingxaki zokopha, iintlungu esifubeni, iingxaki zentliziyo, ukolulwa kweQT potassium, calcium, okanye i-magnesium egazini lakho, ukubetha kwentliziyo okungaqhelekanga, ukusilela kwentliziyo, iingxaki zezintso ngaphandle komhlaza wezintso, okanye iingxaki zesibindi ngaphandle komhlaza wesibindi.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Kuya kufuneka uthathe uvavanyo lokukhulelwa ngaphambi kokuqala unyango. Ukuba ungumfazi okwaziyo ukukhulelwa, kuya kufuneka usebenzise ulawulo lokuzalwa olusebenzayo ngexesha lonyango lwakho kunye neenyanga ezi-6 emva kwedosi yakho yokugqibela. Ukuba uyindoda kunye neqabane lomfazi onokukhulelwa, kuya kufuneka usebenzise ulawulo lokuzalwa olusebenzayo ngexesha lonyango lwakho kunye neenyanga ezi-3 emva kwedosi yakho yokugqibela. Thetha nogqirha wakho malunga neendlela zokulawula ukuzalwa eziza kukusebenzela. Ukuba ukhulelwa ngelixa uthatha i-sorafenib, biza ugqirha ngokukhawuleza. I-Sorafenib inokulimaza umbungu.
• xelela ugqirha wakho ukuba uncelisa okanye ucwangcisa ukuncancisa. Akufanele uncancise ngelixa uthatha i-sorafenib kunye neeveki ezi-2 emva kwedosi yakho yokugqibela.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-sorafenib

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yokulinganisa Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Sorafenib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukudinwa
• ubuthathaka
• ubomvu besikhumba
• ukulahleka kweenwele
• ukurhawuzelela
• isikhumba esomileyo okanye esikhulayo
• Ukuphelelwa ngumdla wokutya
• ukuqhina
• urhudo
• umlomo owomileyo
• ukuhla ukusinda
• intlungu edibeneyo
• ukuba ndindisholo, iintlungu okanye ukurhawuzelelwa zizandla okanye iinyawo
• intloko ebuhlungu

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

• ukugruzuka okanye ukopha okungaqhelekanga
• emnyama kunye / okanye izitulo zokulinda
• Igazi elibomvu ilindle
• ukugabha okunegazi
• ukugabha okubonakala ngathi yindawo yekofu
• ifiva
• iintlungu ezinzima zesisu
• isicaphucaphu
• ukugabha
• iintlungu zesifuba
• ukuqhawukelwa ngumphefumlo
• isiyezi okanye isiqaqa
• ukubila okugqithisileyo
• ngokukhawuleza, ukubetha, okanye ukubetha kwentliziyo okungaqhelekanga
• intloko ebuhlungu ngesiquphe
• ukudideka
• utshintsho kumbono
• ukuxhuzula
• irhashalala
• ububomvu, iintlungu, ukudumba okanye amadyungu ezintendeni zezandla okanye iinyawo
• ukudumba kolusu kunye nokuxobuka
• urhwebo
• ukurhawuzelela
• ubomvu besikhumba
• izilonda zomlomo
• umchamo omnyama
• mthubi ulusu okanye amehlo
• iintlungu kwinxalenye ephezulu yesisu

I-Sorafenib inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• urhudo
• irhashalala okanye ezinye iingxaki zolusu

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-sorafenib. Ugqirha wakho uya kujonga uxinzelelo lwegazi qho ngeveki kwiiveki ezintandathu zokuqala zonyango lwakho kwaye amaxesha ngamaxesha njengoko kufuneka.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Nexavar^®