I-Etravirine

Umxholo

• Ngaphambi kokuba uthathe i-etravirine,
• I-Etravirine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, yeka ukuthatha i-etravirine kwaye ubize ugqirha ngoko nangoko:

I-Etravirine isetyenziswa kunye namanye amayeza ukunyanga usulelo lwe-immunodeficiency virus (HIV) kubantu abadala nakubantwana abaneminyaka emi-2 nangaphezulu abangasancediyo ngokuthatha amanye amayeza e-HIV. I-Etravirine ikudidi lwamayeza abizwa ngokuba yi-non-nucleoside reverse transcriptase inhibitors (NNRTIs). Isebenza ngokunciphisa inani le-HIV egazini. Nangona i-etravirine ingayinyangi i-HIV, inokuwanciphisa amathuba akho okuba ne-immunodeficiency syndrome (i-AIDS) kunye nezifo ezinxulumene ne-HIV ezinje ngezifo ezinzulu okanye umhlaza. Ukuthatha la mayeza kunye nokwabelana ngesondo okukhuselekileyo nokwenza olunye utshintsho kwindlela yokuphila kunokunciphisa umngcipheko wokuhambisa (ukusasaza) intsholongwane kagawulayo kwabanye abantu.

I-Etravirine iza njengecwecwe lokuthatha ngomlomo. Ngokuqhelekileyo kuthathwa emva kokutya kabini ngosuku. Thatha i-etravirine ngamaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-etravirine ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya iipilisi zonke ulwelo, njengamanzi; ungahluleli, ungahlaleli, okanye uzityumze.

Ukuba unengxaki yokuginya iipilisi, zinokunyibilika emanzini. Ukulungiselela, faka iipilisi kwitispuni enye (5 ml) yamanzi (kuphela amanzi, ungasebenzisi naluphi na uhlobo lolwelo) okanye ubuncinci obaneleyo bokugubungela iyeza, kwaye unyanzele kude kube nomxube wobisi. Emva koko yongeza icephe elinye (15 mL) lolwelo njengamanzi okanye ungasebenzisa isiselo esifana nejusi yeorenji okanye ubisi ukuphucula incasa. Yenza hayi xuba amacwecwe ngolwelo olufudumeleyo okanye olushushu okanye isiselo esihlwahlwazayo esifana nesoda. Sela lo mxube ngoko nangoko. Hlanganisa iglasi ngamanzi, ijusi yeorenji, okanye ubisi kwaye uginye yonke imixholo. Phinda inkqubo yokuhlanjululwa kunye nokuginya umxube wokuhlanjululwa amatyeli aliqela ukuqinisekisa ukuba idosi yonke ithathiwe.

I-Etravirine iyanceda ukulawula usulelo lwe-HIV kodwa ayilunyangi. Qhubeka nokuthatha i-etravirine nokuba uziva uphilile. Sukuyeka ukuthatha i-etravirine ngaphandle kokuthetha nogqirha wakho. Ukuba uyeka ukuthatha i-etravirine okanye uphose iidosi, imeko yakho kunokuba nzima ukunyanga. Xa unikezelo lwakho lwe-etravirine luqala ukuba phantsi, fumana ngakumbi kugqirha wakho okanye kwikhemesti.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-etravirine,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-etravirine, nawaphi na amanye amayeza, okanye nasiphi na isithako kwiipilisi ze-etravirine. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo nolungabhaliswanga, iivithamini, kunye nezongezelelo zesondlo ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya oku kulandelayo: ii-anticoagulants ('igazi elincinci') njenge-warfarin (Coumadin, Jantoven); antiarrhythmics (amayeza anyanga ukubetha kwentliziyo okungaqhelekanga) kubandakanya i-amiodarone (Nexterone, Pacerone), bepridil (Vascor), disopyramide (Norpace), flecainide (Tambocor), lidocaine (Xylocaine), mexiletine (Mexitil), propafenone (Rythmol), kunye nequinin ); amayeza athile okunyanga ukuxhuzula okufana ne-carbamazepine (Carbatrol, Tegretol, Teril), phenobarbital (Luminal), kunye ne phenytoin (Dilantin, Phenytek); i-clarithromycin (i-Biaxin, kwi-Prevpac); iyeza elinciphisa i-cholesterol (ii-statins) kubandakanya i-atorvastatin (Lipitor), fluvastatin (Lescol), lovastatin (Advicor, Altoprev, Mevacor), rosuvastatin (Crestor), kunye ne-simvastatin (Vytorin, Zocor); iklopidogrel (iPlavix); diazepam (Valium); dexamethasone; amayeza athile acinezela amajoni omzimba njenge-cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), kunye ne-tacrolimus (Prograf); amayeza okunyanga ukungasebenzi kakuhle kwe-erectile kubandakanya i-sildenafil (Viagra), tadalafil (Cialis), kunye ne-vardenafil (Levitra); amayeza okunyanga usulelo lomngundo kubandakanya i-fluconazole (Diflucan), itraconazole (Onmel, Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), kunye ne-voriconazole (Vfend); imethadone (iDolophine); amanye amayeza anyanga i-HIV kubandakanya amprenavir (Agenerase), atazanavir (Reyataz), delavirdine (Rescriptor), efavirenz (Sustiva, eAtripla), fosamprenavir (Lexiva), indinavir (Crixivan), lopinavir (e Kaletra), nelfinavir (Virac) kunye nevirapine (Viramune) ritonavir (Norvir, eKaletra), kunye netipranavir (Aptivus); irifabutin (Mycobutin); irifampin (Rifadin, Rifater, Rifamate); kunye ne-rifapentine (Priftin). Uninzi lwamanye amayeza anokusebenzisana ne-etravirine, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu. Sukuqala ngokuthatha amayeza amatsha ngelixa uthatha i-etravirine ngaphandle kokuqala uthethe nogqirha okanye usokhemesti.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
• xelela ugqirha wakho ukuba ukhe unesifo sesibindi, kubandakanya i-hepatitis.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Ukuba ukhulelwa ngelixa uthatha i-etravirine, tsalela ugqirha wakho.
• akufuneki uncelise xa wosulelwe yi-HIV okanye uthatha i-etravirine.
• Kuya kufuneka uyazi ukuba amanqatha omzimba wakho anokunyuka okanye ahambele kwiindawo ezahlukeneyo zomzimba wakho ezinje ngamabele akho, intamo, isifuba, isisu, kunye nomqolo ongaphezulu. Ukuphulukana namafutha kwimilenze yakho, iingalo, kunye nobuso nako kunokwenzeka.
• Kuya kufuneka uyazi ukuba ngelixa uthatha amayeza ukunyanga usulelo lwe-HIV, amajoni akho omzimba angomelela kwaye aqale ukulwa nezinye izifo ezazisele zisemzimbeni wakho. Oku kunokubangela ukuba ube neempawu zolu sulelo. Ukuba uneempawu ezintsha okanye eziba mandundu emva kokuqala unyango nge-etravirine, qiniseka ukuxelela ugqirha wakho.

Thetha nogqirha wakho malunga nokutya igrapefruit kunye nokusela ijusi yegrapefruit ngelixa uthatha eli yeza.

Ukuba uyakhumbula ukuba uphose ukuthatha idosi ngaphakathi kweeyure ezingama-6 zexesha oqhele ukuthatha ngalo i-etravirine, thatha idosi ephosiweyo emva kwesidlo ngokukhawuleza, kwaye uthathe idosi elandelayo ngexesha elimiselweyo rhoqo. Nangona kunjalo, ukuba ukhumbula ngaphezulu kweeyure ezingama-6 emva kwexesha oqhele ukuthatha ngalo idosi yakho, linda kwaye uthathe idosi elandelayo ye-etravirine ngokweshedyuli yakho yesiqhelo yedosi. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Etravirine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• intlungu zesisu
• urhudo
• intloko ebuhlungu
• ukwanda koxinzelelo lwegazi
• iintlungu, ukutshisa, ukuba ndindisholo, okanye ukubetha ezandleni okanye ezinyaweni

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, yeka ukuthatha i-etravirine kwaye ubize ugqirha ngoko nangoko:

• irhashalala
• ububomvu, amaqhuma, okanye amadyunguza kulusu okanye emlonyeni
• bomvu okanye ukudumba kwamehlo
• ukudumba kobuso
• umqala obuhlungu, ukukhohlela, umkhuhlane, ukubanda, okanye ezinye iimpawu zosulelo
• imvakalelo yokugula ngokubanzi
• ukudinwa
• izihlunu okanye amalungu ngokudibeneyo
• mthubi ulusu okanye amehlo
• umchamo omnyama-mnyama
• ilindle elimhlophe
• iintlungu kwinxalenye ephezulu yesisu
• Ukuphelelwa ngumdla wokutya

I-Etravirine inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Gcina iipokotho ezintathu ze-desiccant (i-arhente yokomisa) kwibhotile yeyeza ukugcina iipilisi zomile. Musa ukuzitya iipokotho zecicicant.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho angayalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-etravirine.

Ngaphambi kokuba uvavanywe elebhu, xelela ugqirha wakho kunye nabasebenzi baselebhu ukuba uthatha i-etravirine.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Gcina uluhlu lwamayeza akho kwaye ulibonise kugqirha nakwikhemesti xa ufumana iyeza elitsha.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Ukungafezeki^®