Inaliti ye-Alemtuzumab (Isifo seLymphocytic Leukemia)

Umxholo

• Ngaphambi kokufumana inaliti ye-alemtuzumab,
• Inaliti ye-Alemtuzumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:
• Iimpawu libanda kungaquka oku kulandelayo:

Inaliti ye-Alemtuzumab (Campath) ifumaneka kuphela nangona inkqubo yokuhambisa ethintelweyo (Inkqubo yokuhanjiswa kweCampath). Ukuze ufumane inaliti ye-alemtuzumab (Campath) ugqirha wakho kufuneka abhaliswe kule nkqubo, kwaye alandele iimfuno. Inkqubo yokuhanjiswa kweCampath iya kuthumela amayeza ngqo kugqirha, esibhedlele, okanye ekhemesti.

Inaliti ye-Alemtuzumab inokubangela ukwehla kwenani leeseli zegazi ezenziwe ngumongo wethambo lakho. Ukuba unazo naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko: ukugruzuka okungaqhelekanga okanye ukopha, amabala egazi abomvu bubomvu okanye mfusa emzimbeni wakho, ulusu olumhlophe, ubuthathaka, okanye ukudinwa okugqithisileyo. Uya kudinga ukuthatha amanyathelo okhuseleko ukuthintela ukwenzakala ngexesha lonyango lwakho kuba ungopha kakhulu kwizicucu ezincinci okanye kwizikrelemnqa. Hlamba amazinyo akho ngebrashi yamazinyo ethambileyo, sebenzisa isitshetshe sombane ukuba uchetyiwe, kwaye uphephe ukunxibelelana nezemidlalo kunye nezinye izinto ezinokubangela ukwenzakala.

Inaliti ye-Alemtuzumab inokunciphisa ukubanakho kwakho ukulwa usulelo kwaye inyuse umngcipheko wokuba ufumane usulelo olubi okanye olusongela ubomi. Biza ugqirha wakho ngokukhawuleza ukuba uvelisa naziphi na iimpawu zosulelo ezifana nomkhuhlane, ukukhohlela, umqala obuhlungu, okanye inxeba elibomvu, ukukhupha ubofu, okanye ukucotha ukuphola.

Kuya kufuneka uthathe amanyathelo okhuseleko ukunciphisa umngcipheko wosulelo ngexesha lonyango lwakho ngenaliti ye-alemtuzumab. Ugqirha wakho uya kukunika amayeza athile okuthintela usulelo. Uya kuwathatha la mayeza ngexesha lonyango lwakho kwaye ubuncinci iinyanga ezi-2 emva konyango lwakho. Thatha la mayeza ngokuchanekileyo. Kufuneka kwakhona uhlambe izandla zakho rhoqo kwaye uphephe abantu abanesifo esosulelayo esifana nokukhohlela nemikhuhlane. Ukuba ufuna naluphi na uhlobo lotofelo-gazi ngexesha lonyango lwakho ngenaliti ye-alemtuzumab, kuya kufuneka ufumane kuphela iimveliso zegazi ezikhanyisiweyo (iimveliso zegazi ezinyangiweyo ukuthintela impendulo ethile enokubakho kubantu abenze buthathaka amajoni omzimba).

Unokufumana impendulo enzulu okanye ebulalayo ngelixa ufumana idosi yenaliti ye-alemtuzumab. Uya kufumana idosi nganye yamayeza kwindawo yonyango, kwaye ugqirha wakho uya kukujonga ngononophelo ngelixa ufumana amayeza. Ugqirha wakho uya kukuyalela amayeza athile ukukhusela ezi mpendulo. Uya kuthatha la mayeza kungekudala ngaphambi kokuba ufumane idosi nganye ye-alemtuzumab. Ugqirha wakho uyakuqala kwidosi esezantsi ye-alemtuzumab kwaye ngokuthe ngcembe wandise idosi yakho ukuvumela umzimba wakho ukuba uhlengahlengiso kunyango. Ukuba ufumana naziphi na kwezi mpawu zilandelayo ngexesha okanye emva kokufakwa, xelela ugqirha ngoko nangoko: umkhuhlane; Ukugodola; isicaphucaphu; ukugabha; imihlathi irhashalala; ukurhawuzelela; ubunzima bokuphefumla okanye ukugwinya; ukuphefumla okucothayo; ukuqinisa umqala; ukudumba kwamehlo, ubuso, umlomo, imilebe, ulwimi okanye umqala; ukudakumba; isiyezi; intloko emhlophe; isiqaqa; ukukhawuleza kwentliziyo okanye okungaqhelekanga; okanye iintlungu esifubeni.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile ngexesha nasemva konyango lwakho ukujonga impendulo yomzimba wakho kwisitofu se-alemtuzumab.

Thetha nogqirha wakho malunga neengozi zokufumana inaliti ye-alemtuzumab.

Inaliti ye-Alemtuzumab isetyenziselwa ukunyanga i-B-cell ye-lymphocytic leukemia (B-CLL; umhlaza okhulayo kancinci apho uninzi lohlobo oluthile lweeseli ezimhlophe zegazi luqokelela emzimbeni). I-Alemtuzumab ikwiklasi yamayeza abizwa ngokuba ngamachiza omzimba. Isebenza ngokwenza amajoni omzimba atshabalalise iiseli zomhlaza.

I-Alemtuzumab ikwafumaneka njengenaliti (i-Lemtrada) esetyenziselwa ukunyanga i-multiple sclerosis (isifo apho imithambo-luvo ingasebenzi kakuhle; unokufumana ubuthathaka, ukuba ndindisholo, ukuphulukana nokulungelelaniswa kwemisipha kunye neengxaki ngombono, intetho kunye nolawulo lwesinyi ). Le monograph inika kuphela ulwazi malunga nenaliti ye-alemtuzumab (Campath) ye-B-CLL. Ukuba ufumana i-alemtuzumab ye-multiple sclerosis, funda i-monograph enesihloko esithi Inaliti ye-Alemtuzumab (Multiple Sclerosis).

Inaliti ye-Alemtuzumab iza njengesisombululo (ulwelo) sokutofelwa ngaphakathi (emthanjeni) ngaphezulu kweeyure ezi-2 ngugqirha okanye umongikazi esibhedlele okanye kwiofisi yezonyango. Ekuqaleni, inaliti ye-alemtuzumab ihlala inikwa ngeedosi ezonyukayo ngokuthe ngcembe iintsuku ezi-3 ukuya kwezi-7 ukuvumela umzimba ukuba uhlengahlengiso kunyango. Nje ukuba umzimba uhlengahlengise kwidosi efunekayo yenaliti ye-alemtuzumab, iyeza lihlala linikezelwa kathathu ngeveki kwezinye iintsuku (zihlala ngoMvulo, uLwesithathu, nangoLwesihlanu) ukuya kuthi ga kwiiveki ezili-12.

Amayeza owafumanayo ngaphambi kwedosi nganye yenaliti ye-alemtuzumab inokukwenza ulale. Uya kufuna ukucela ilungu losapho okanye umhlobo ukuba eze nawe xa ufumana amayeza akho kwaye akugoduse emva koko.

Nangona imeko yakho inokuphuculwa kwakamsinya emva kweeveki ezi-4 ukuya kwezi-6 emva kokuba uqale unyango ngenaliti ye-alemtuzumab, unyango lwakho luya kuhlala iiveki ezili-12. Ugqirha wakho uya kuthatha isigqibo sokuba aqhubeke nonyango kwaye anokuhlengahlengisa idosi yakho ngokuxhomekeke ekubeni lisebenza kanjani na unyango lwakho nakwiziphumo ebezingalindelekanga ohlangabezana nazo.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana inaliti ye-alemtuzumab,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa inaliti ye-alemtuzumab okanye nawaphi na amanye amayeza.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha.
• xelela ugqirha wakho ukuba ukhe wakha naziphi na iimeko zonyango.
• xelela ugqirha wakho ukuba wena okanye iqabane lakho ukhulelwe okanye ucwangcise ukukhulelwa. Kuya kufuneka uthathe uvavanyo lokukhulelwa ngaphambi kokuqala unyango kwaye usebenzise ulawulo lokuzalwa ukuthintela ukukhulelwa ngexesha lonyango lwakho kunye neenyanga ezi-3 emva kwedosi yakho yokugqibela. Ukuba ukhulelwa ngexesha lonyango lwakho ngenaliti ye-alemtuzumab, tsalela umnxeba kwangoko. I-Alemtuzumab inokwenzakalisa umntwana ongekazalwa.
• xelela ugqirha wakho ukuba uncelisa. Musa ukuncancisa ngexesha lonyango nge-alemtuzumab kunye neenyanga ezi-3 emva kwedosi yokugqibela.
• awunazo izitofu zokugonya eziphilayo okanye kungekudala emva konyango lwakho ngenaliti ye-alemtuzumab ngaphandle kokuthetha nogqirha wakho. Abasetyhini abafumana inaliti ye-alemtuzumab ngexa ukhulelweyo kufuneka bathethe nogqirha wabantwana njengoko usana lwabo lungenakho ukufumana izitofu zokugonya eziphilayo ixesha elithile.
• Kuya kufuneka uyazi ukuba eli yeza linciphisa ukuchuma emadodeni nakwabasetyhini. Thetha nogqirha wakho malunga neengozi zokufumana i-alemtuzumab.
• ukuba uyenziwa utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba ufumana inaliti ye-alemtuzumab.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Inaliti ye-Alemtuzumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• isisu esibuhlungu
• urhudo
• Ukuphelelwa ngumdla wokutya
• izilonda zomlomo
• intloko ebuhlungu
• ixhala
• ubunzima bokulala okanye ukulala
• ukushukuma okungalawulekiyo kwilungu lomzimba
• iintlungu zemisipha

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

• ukujinga kwelinye icala lobuso; ubuthathaka ngequbuliso okanye ukuba ndindisholo kwengalo okanye umlenze, ngakumbi kwicala elinye lomzimba; okanye kunzima ukuthetha okanye ukuqonda
• ukudumba kwemilenze namaqatha, ukutyeba, ukudinwa. okanye umchamo we-foamy (unokwenzeka iinyanga okanye iminyaka emva kwedosi yakho yokugqibela)

I-Alemtuzumab inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• Ukuqina komqala
• ubunzima bokuphefumla
• ukukhohlela
• ukuncipha kokuchama
• ukugruzuka okanye ukopha okungaqhelekanga
• amabala abomvu okanye amfusa eluswini
• ulusu oluthuthu
• ubuthathaka
• ukudinwa kakhulu
• umqala obuhlungu, umkhuhlane, ukubanda, kunye neminye imiqondiso yosulelo
• isicaphucaphu
• ukugabha
• urhwebo
• irhashalala
• ukurhawuzelela
• ukudumba kwamehlo, ubuso, umlomo, umqala, imilebe, okanye ulwimi
• ukukhawuleza kwentliziyo okanye okungaqhelekanga
• isiqaqa
• iintlungu zesifuba

Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nenaliti ye-alemtuzumab.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• ICampath^®