Umbhali: Clyde Lopez
Umhla Wokudalwa: 25 Eyekhala 2021
Hlaziya Umhla: 15 Eyenkanga 2024
Anonim
Comparing CV Safety of Febuxostat and Allopurinol
Ividiyo: Comparing CV Safety of Febuxostat and Allopurinol

Umxholo

Abantu abathatha i-febuxostat banokuba semngciphekweni omkhulu wokufa okunxulumene nentliziyo kunabantu abathatha amanye amayeza kunyango lwegawuthi. Xelela ugqirha wakho ukuba ukhe unesifo sentliziyo okanye isifo sentliziyo okanye ukubetha. Ukuba unazo naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko: iintlungu esifubeni, ukuphefumla kancinci, ukubetha kwentliziyo okukhawulezileyo okanye okungaqhelekanga, ukuba ndindisholo okanye ubuthathaka kwelinye icala lomzimba wakho, isiyezi, ukuphelelwa ngamandla, intetho edikidiki, umbono oqaqambileyo, okanye ngokukhawuleza intloko ebuhlungu.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango ngefebuxostat kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-febuxostat.


IFebuxostat isetyenziselwa ukunyanga i-gout kubantu abadala abangakhange banyangwe ngempumelelo okanye abangakwaziyo ukuthatha i-allopurinol (Aloprim, Zyloprim). Igawuthi luhlobo lwesifo samathambo apho i-uric acid, eyenzeka ngokwendalo emzimbeni, yakha kumalungu kwaye ibangela uhlaselo olukhawulezileyo olubomvu, ukudumba, iintlungu kunye nobushushu kwilungu elinye okanye nangaphezulu. UFebuxostat ukwiklasi yamayeza abizwa ngokuba yi-xanthine oxidase inhibitors. Isebenza ngokunciphisa inani le-uric acid eyenziwe emzimbeni. IFebuxostat isetyenziselwa ukuthintela ukuhlaselwa yintsholongwane kodwa ingekunyangwa yakuba yenzekile.

IFebuxostat iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kanye ngemini kunye okanye ngaphandle kokutya. Thatha i-febuxostat malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-febuxostat ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ugqirha wakho angalonyusa umthamo wakho we-febuxostat emva kweeveki ezi-2 ukuba uvavanyo lwaselebhu lubonisa ukuba usene-uric acid eninzi egazini lakho.


Kungathatha iinyanga ezininzi ngaphambi kokuba i-febuxostat iqale ukuthintela ukuhlaselwa yintsholongwane. IFebuxostat ingalonyusa inani lohlaselo lwe-gout kwiinyanga zokuqala ezimbalwa zonyango lwakho. Ugqirha wakho unokumisela elinye iyeza elinje nge-colchicine (Colcyrs, Mitigare) okanye ichiza elichasayo (i-NSAID) ukuthintela uhlaselo lwe-gout kwiinyanga ezintandathu zokuqala zonyango. Qhubeka nokuthatha i-febuxostat nokuba uhlaselwa yi-gout ngexesha lonyango lwakho kwangoko.

IFebuxostat ilawula igawuthi kodwa ayiyinyangi. Qhubeka uthathe i-febuxostat nokuba uziva uphilile. Sukuyeka ukuthatha i-febuxostat ngaphandle kokuthetha nogqirha wakho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-febuxostat,

  • xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-febuxostat, i-allopurinol, nawaphi na amanye amayeza, okanye naziphi na izithako ezikwiipilisi zefebuxostat. Buza usokhemesti wakho uluhlu lwezithako.
  • xelela ugqirha wakho ukuba uthatha i-azathioprine (Azasan, Imuran) okanye i-mercaptopurine (Purinethol, Purixan). Ugqirha wakho uya kukuxelela ukuba ungathathi i-febuxostat ukuba uthatha elinye okanye ngaphezulu kwala mayeza.
  • xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ngokukhankanya i-theophylline (Elixophyllin, Theo-24, abanye) okanye amayeza e-chemotherapy. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
  • xelela ugqirha wakho ukuba ukhe wafakelwa ilungu lomzimba; umhlaza; I-Lesch-Nyhan syndrome (isifo esizuzwe njengelifa esibangela amanqanaba aphezulu e-uric acid egazini, iintlungu ezidibeneyo, kunye neengxaki zokuhamba nokuziphatha); okanye isifo sezintso okanye sesibindi.
  • xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-febuxostat, tsalela ugqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.


Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

IFebuxostat inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba enye yezi mpawu inzima okanye ayihambi:

  • isicaphucaphu
  • intlungu edibeneyo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu, okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela ugqirha wakho kwangoko:

  • irhashalala; ulusu lubomvu okanye iintlungu; ukudumba kwemilebe, amehlo okanye umlomo; ulusu luyaxobuka; okanye umkhuhlane kunye nezinye iimpawu ezinje ngomkhuhlane
  • ubuso obudumbileyo, imilebe, umlomo, ulwimi okanye umqala
  • Amehlo atyheli okanye ulusu; umchamo omnyama; okanye iintlungu okanye ukungaphatheki kakuhle kwindawo ephezulu yesisu

IFebuxostat inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi, kude nokukhanya, kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-febuxostat.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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Ukuhlaziywa kokugqibela-05/01/2019

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