Saxagliptin

Umxholo

• Ngaphambi kokuba uthathe i-saxagliptin,
• Eli yeza linokubangela utshintsho kwiswekile yegazi lakho. Kuya kufuneka uyazi iimpawu zeswekile esezantsi kunye ephezulu yegazi kwaye wenzeni ukuba unayo le miqondiso.
• I-Saxagliptin inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, yeka ukuthatha i-saxagliptin kwaye ubize ugqirha ngoko nangoko:

I-Saxagliptin isetyenziswa kunye nokutya kunye nokuzilolonga ukunciphisa amanqanaba eswekile yegazi kwizigulana ezinesifo seswekile sesi-2 (imeko apho iswekile esegazini iphezulu kakhulu kuba umzimba awuvelisi okanye usebenzise i-insulin ngesiqhelo). I-Saxagliptin ikwiklasi yamayeza abizwa ngokuba yi-dipeptidyl peptidase-4 (DPP-4) inhibitors. Isebenza ngokwandisa inani le-insulin eveliswa ngumzimba emva kokutya xa iswekile yegazi iphezulu. I-Saxagliptin ayisetyenziswanga ukunyanga isifo seswekile sokuqala (imeko apho umzimba ungayivelisi i-insulin kwaye, ngenxa yoko, awunakho ukulawula isixa seswekile egazini) okanye isifo seswekile ketoacidosis (imeko ebucayi enokuthi ikhule ukuba iswekile ephezulu yegazi ayinyangwa. ).

Ixesha elingaphezulu, abantu abanesifo seswekile kunye neswekile ephezulu yegazi banokuba neengxaki ezinzulu okanye ezisongela ubomi, kubandakanya isifo sentliziyo, ukubetha, iingxaki zezintso, ukonakala kwemithambo-luvo kunye neengxaki zamehlo. Ukuthatha amayeza, ukwenza utshintsho kwindlela yokuphila (umzekelo, ukutya, ukwenza umthambo, ukuyeka ukutshaya), kunye nokujonga iswekile yegazi rhoqo kunokunceda ukulawula isifo seswekile kunye nokuphucula impilo yakho. Olu nyango lunokunciphisa amathuba akho okuhlaselwa sisifo sentliziyo, ukubetha, okanye ezinye iingxaki ezinxulumene nesifo seswekile ezinje ngokusilela kwezintso, ukulimala kwentliziyo (ukubindeka, imilenze ebandayo okanye iinyawo; ukunciphisa amandla ezesondo kumadoda nabasetyhini), iingxaki zamehlo, kubandakanya notshintsho okanye ukulahleka kombono, okanye isifo seentsini. Ugqirha wakho kunye nabanye ababoneleli ngempilo bayakuthetha nawe ngeyona ndlela yokulawula isifo sakho seswekile.

I-Saxagliptin iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kanye ngemini kunye okanye ngaphandle kokutya. Thatha i-saxagliptin malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-saxagliptin ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

I-Saxagliptin ilawula uhlobo lwe-2 yeswekile kodwa ayiyinyangi. Qhubeka uthathe i-saxagliptin nokuba uziva uphilile. Sukuyeka ukuthatha i-saxagliptin ungakhange uthethe nogqirha wakho.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-saxagliptin kwaye ngalo lonke ixesha uzalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-saxagliptin,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-saxagliptin, nawaphi na amanye amayeza, okanye naziphi na izithako ezikwiipilisi ze-saxagliptin. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: amayeza athile okubambisa anje nge-itraconazole (Onmel, Sporanox) kunye ne ketoconazole (Nizoral); i-clarithromycin (i-Biaxin); amayeza athile e-HIV (intsholongwane yokungakhuseleki komzimba) okanye i-AIDS (efunyenwe yintsholongwane) efana ne-atazanavir (Reyataz, e-Evotaz), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, e Kaletra), kunye ne-saquinavir (Invirase); I-insulin okanye amayeza omlomo weswekile afana ne-chlorpropamide (Diabinese), glimepiride (Amaryl, e-Duetact), glipizide (Glucotrol), glyburide (Diabeta, Glynase, in Glucovance), nateglinide (Starlix), pioglitazone (Actos, in Actoplus Met, in Duetact), repaglinide (Prandin, in Prandimet), rosiglitazone (Avandia), tolazamide, kunye ne tolbutamide; nefazodone; kunye ne-telithromycin (ayisafumaneki e-US; Ketek). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye ukujonga ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba uyasela okanye wakha wasela izixa ezikhulu zotywala, ukuba ukhe wanaso isifo sokudumba kwenkunkuma (ukudumba kwepancreas), amatye enyongo, amanqanaba aphezulu e-triglycerides (izinto ezinamafutha) egazini lakho, ukusilela kwentliziyo, isifo seswekile ketoacidosis, okanye isifo sezintso.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-saxagliptin, tsalela ugqirha wakho.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-saxagliptin.
• thetha nogqirha wakho malunga nento ekufuneka uyenzile ukuba wenzakele okanye uba nomkhuhlane okanye usulelo. Ezi meko zinokuchaphazela iswekile yegazi kunye nenani le-saxagliptin onokuyifuna.

Qiniseka ukuba ulandela yonke imithambo kunye nezincomo zokutya ezenziwe ngugqirha wakho okanye ugqirha otya ukutya. Kubalulekile ukutya ukutya okusempilweni, ukuzilolonga rhoqo, kwaye unciphise umzimba xa kukho imfuneko yoko. Oku kuya kunceda ukulawula isifo seswekile kunye nokunceda i-saxagliptin isebenze ngokufanelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Musa ukuthatha idosi ephindwe kabini ukuyenzela enye oyiphosileyo ngaphandle kokuba ugqirha wakho ukuxelele ukuba kufanele.

Eli yeza linokubangela utshintsho kwiswekile yegazi lakho. Kuya kufuneka uyazi iimpawu zeswekile esezantsi kunye ephezulu yegazi kwaye wenzeni ukuba unayo le miqondiso.

I-Saxagliptin inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• umqala obuhkungu
• intloko ebuhlungu
• intlungu edibeneyo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, yeka ukuthatha i-saxagliptin kwaye ubize ugqirha ngoko nangoko:

• irhashalala
• urhwebo
• ulusu luyaxobuka
• ukurhawuzelela
• ukudumba kobuso, imilebe, ulwimi okanye umqala
• ubunzima bokuphefumla okanye ukugwinya
• ukudinwa
• iintlungu eziqhubekayo, eziqala phezulu ngasekhohlo okanye embindini wesisu kodwa zisenokunabela ngasemva
• ukugabha
• Ukuphelelwa ngumdla wokutya
• ukudinwa kakhulu
• ukuphefumla kancinci, ngakumbi xa ulele phantsi
• ukudumba kweenyawo, amaqatha okanye imilenze
• ukukhawuleza ukutyeba

I-Saxagliptin inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuthi aodole iimvavanyo ezithile zaselebhu ngaphambi nangexesha lonyango lwakho nge-saxagliptin ukujonga impendulo yomzimba wakho kuyo. Iswekile yegazi lakho kunye ne-hemoglobin eglycosylated (HbA1c) kufuneka ihlolwe rhoqo ukumisela impendulo yakho kwi-saxagliptin. Ugqirha wakho unokukuxelela nendlela yokujonga impendulo yakho kwi-saxagliptin ngokulinganisa igazi okanye umchamo wamanqanaba eswekile ekhaya. Landela le miyalelo ngononophelo.

Kufuneka usoloko unxibe isacholo esichaza isifo seswekile ukuze uqiniseke ukuba ufumana unyango olufanelekileyo ngexesha likaxakeka.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• UOnglyza^®

• UKombiglyze^® I-XR (iqulethe iMetformin, iSaxagliptin)
• Qtern^® (Equlathe iDapagliflozin, Saxagliptin)
• Qternmet^® XR (equlathe iDapagliflozin, Metformin, Saxagliptin)