Inaliti yeBusulfan

Umxholo

• Phambi kokufumana inaliti ye-busulfan,
• I-Busulfan inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:
• Iimpawu libanda kungaquka oku kulandelayo:

Inaliti yeBusulfan inokubangela ukwehla okumandla kwenani leeseli zomongo wethambo lakho. Xelela ugqirha wakho kunye nosokhemesti ngawo onke amayeza owathathayo. Ukuba ufumana i-busulfan namanye amayeza anokubangela ukubalwa kwegazi okuphantsi, iziphumo ebezingalindelekanga zinokuba nzima kakhulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, biza ugqirha ngoko nangoko: umkhuhlane, umqala obuhlungu, ukukhohlela okuqhubekayo nokuxinana, okanye ezinye iimpawu zosulelo; ukopha okungaqhelekanga okanye ukugruzuka.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo zaselebhu ngaphambili, ngexesha nasemva konyango lwakho ukujonga impendulo yomzimba wakho kwi-busulfan ukubona ukuba iiseli zakho zegazi ziyachaphazeleka kweli chiza.

I-Busulfan inokunyusa umngcipheko wokuba uphuhlise eminye imihlaza. Thetha nogqirha wakho malunga neengozi zokufumana i-busulfan.

Inaliti yeBusulfan isetyenziselwa ukunyanga uhlobo oluthile lwe-leukemia engapheliyo (i-CML; uhlobo lomhlaza weeseli ezimhlophe zegazi) ngokudityaniswa namanye amayeza okutshabalalisa umongo wethambo kunye neeseli zomhlaza ukulungiselela ukufakwa komongo wethambo. I-Busulfan ikwiklasi yamayeza abizwa ngokuba ziiarhente ze-alkylating. Isebenza ngokunciphisa okanye ukumisa ukukhula kweeseli zomhlaza emzimbeni wakho.

I-Busulfan iza njengesisombululo (ulwelo) ukuba sinikezwe ngaphakathi (emthanjeni) ngaphezulu kweeyure ezi-2 ngugqirha okanye ngumongikazi kwiziko lonyango. Ihlala inikwa rhoqo emva kweeyure ezingama-6 kwiintsuku ezi-4 (iyonke iidosi ezili-16) ngaphambi kokufakwa komongo wethambo.

Inaliti ye-Busulfan inokubangela ukuxhuzula ngexesha lonyango ngamayeza. Ugqirha wakho uya kukunika elinye iyeza ukunceda ukuthintela ukuxhuzula ngaphambi kunye nangexesha lonyango ngenaliti ye-busulfan.

Inaliti yeBusulfan ikwasetyenziswa ngokudibeneyo namanye amachiza ukutshabalalisa umongo wethambo kunye neeseli zomhlaza ukulungiselela ukufakwa komongo wethambo kubantu abanezinye iintlobo zomhlaza.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Phambi kokufumana inaliti ye-busulfan,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-busulfan, nawaphi na amanye amayeza, okanye nasiphi na isithako senaliti ye-busulfan. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: acetaminophen (Tylenol); i-clozapine (iClozaril, iFazaClo); i-cyclosporine (iSandimmune, iGengraf, iNeoral); itraconazole (Sporanox); amayeza okugula ngengqondo kunye nesicaphucaphu; okanye meperidine (Demerol). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-busulfan, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba wakhe wafumana unyango ngemitha okanye enye ichemotherapy okanye wakha waxhuzula okanye wenzakala entloko.
• Kuya kufuneka uyazi ukuba i-busulfan inokuphazamisa umjikelo oqhelekileyo wokuya exesheni (ixesha) kwabasetyhini, inokumisa ukuveliswa kwesidoda emadodeni, kwaye kunokubangela ukungachumi (ubunzima bokukhulelwa). Nangona kunjalo, awufanelanga ukucinga ukuba wena okanye iqabane lakho aninakukhulelwa. Tshela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye ukuncancisa. Akufanele ucwangcise ukuba nabantwana ngelixa ufumana i-chemotherapy okanye okwethutyana emva konyango. (Thetha nogqirha wakho ukuze ufumane iinkcukacha ezithe vetshe.) Sebenzisa indlela ethembekileyo yolawulo lokuzalwa ukuthintela ukukhulelwa. Ukuba ukhulelwe ngelixa ufumana i-busulfan, tsalela umnxeba kwangoko. I-Busulfan inokulimaza umbungu.

I-Busulfan inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• urhudo
• Ukuphelelwa ngumdla wokutya
• ukuhla ukusinda
• ukuqhina
• izilonda emlonyeni nasemqaleni
• umlomo owomileyo
• intloko ebuhlungu
• ubunzima bokulala okanye ukulala
• ukuziva uxhalabile ngokungaqhelekanga okanye ukhathazekile
• isiyezi
• ukudumba kobuso, iingalo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• iintlungu zesifuba
• ngokudibeneyo, izihlunu okanye iintlungu zomqolo
• irhashalala
• ukurhawuzelela nolusu olomileyo
• isikhumba esimnyama
• ukulahleka kweenwele

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:

• mnyama, ilindle
• umchamo obomvu
• ukugabha
• isisu esibuhlungu
• ukudinwa okungaqhelekanga okanye ubuthathaka
• ubunzima bokuphefumla
• ukuxhuzula

I-Busulfan inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Eli yeza liya kugcinwa esibhedlele okanye kwiziko lonyango apho ufumana idosi nganye

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• mnyama, ilindle
• umchamo obomvu
• ukugruzuka okanye ukopha okungaqhelekanga
• ukudinwa okungaqhelekanga okanye ubuthathaka

Gcina lonke ixesha lokudibana nogqirha wakho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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