Inaliti yeCarfilzomib

Umxholo

• Ngaphambi kokufumana inaliti ye-carfilzomib,
• Inaliti yeCarfilzomib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu okanye ezo zidweliswe kumacandelo OKHUSELEKO NOKUQHELEKILEYO, tsalela ugqirha wakho:
• Iimpawu libanda kungaquka oku kulandelayo:

Inaliti yeCarfilzomib isetyenziswa yodwa kwaye idityaniswe ne-dexamethasone, daratumumab kunye ne-dexamethasone, okanye i-lenalidomide (Revlimid) kunye ne-dexamethasone ukunyanga abantu abane-myeloma (uhlobo lomhlaza womongo wethambo) esele baphathwa ngamanye amayeza. UCarfilzomib ukwiklasi yamayeza abizwa ngokuba zii-proteasome inhibitors. Isebenza ngokumisa okanye ukunciphisa ukukhula kweeseli zomhlaza emzimbeni wakho.

ICarfilzomib iza njengomgubo oxutywe nolwelo ukuze ifakwe ngaphakathi ngaphakathi (emthanjeni). I-Carfilzomib inikwa ngugqirha okanye ngumongikazi kwiofisi yezonyango okanye eklinikhi ihlala isithuba semizuzu eli-10 okanye engama-30. Inokunikwa iintsuku ezi-2 zilandelelana veki nganye iiveki ezi-3 zilandelwe lixesha leentsuku ezili-12 lokuphumla okanye inokunikwa kube kanye ngeveki iiveki ezi-3 zilandelwe lixesha lokuphumla leentsuku ezili-13. Ubude bonyango buya kuxhomekeka kwindlela ophendula ngayo emzimbeni wakho kunyango.

Inaliti yeCarfilzomib inokubangela ukusabela okuqatha okanye okusongela ubomi ukuya kuthi ga kwiiyure ezingama-24 emva kokufumana idosi yamayeza. Uya kufumana amayeza athile ukunceda ukuthintela impendulo ngaphambi kokuba ufumane idosi nganye ye-carfilzomib. Xelela ugqirha wakho kwangoko ukuba unazo naziphi na kwezi mpawu emva konyango lwakho: umkhuhlane, ukugodola, ukudibana okanye iintlungu zemisipha, ukugungxula okanye ukudumba kobuso, ukudumba okanye ukuqinisa umqala, ukugabha, ukuba buthathaka, ukuphefumla kancinci, isiyezi okanye isiqaqa, okanye ukuqina kwesifuba okanye iintlungu.

Qiniseka ukuba uxelela ugqirha wakho indlela oziva ngayo ngexesha lonyango lwakho. Ugqirha wakho angayeka unyango lwakho okwethutyana okanye anciphise idosi yakho ye-carfilzomib ukuba ufumana iziphumo ebezingalindelekanga zonyango.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana inaliti ye-carfilzomib,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-carfilzomib, nawaphi na amanye amayeza, okanye naziphi na izithako kwiinaliti ze-carfilzomib. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: izinto zokucwangcisa zehomoni (iipilisi zolawulo lokuzalwa, iipatches, iiringi, ukufakelwa, kunye neenaliti) okanye i-prednisone (iRayos). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe wasilela kwentliziyo, wahlaselwa sisifo sentliziyo, ukubetha kwentliziyo ngendlela engaqhelekanga, okanye ezinye iingxaki zentliziyo; igazi elonyukayo; okanye usulelo lwe-herpes (izilonda ezibandayo, i-shingles, okanye izilonda zangasese). Xelela ugqirha wakho ukuba unesibindi okanye isifo sezintso okanye ukwidialysis.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa, okanye ukuba ucwangcisa ukuba notata umntwana. Wena okanye iqabane lakho akufuneki ukuba ukhulelwe ngelixa ufumana i-carfilzomib. Ukuba ungumfazi, kufuneka uthathe uvavanyo lokukhulelwa ngaphambi kokuba uqale unyango kwaye kufuneka usebenzise ulawulo lokuzalwa ukukhusela ukukhulelwa ngexesha lonyango lwakho nge-carfilzomib kunye neenyanga ezi-6 emva kwethamo lakho lokugqibela. Ukuba uyindoda, wena kunye neqabane lakho kufuneka nisebenzise iindlela zolawulo lokuzalwa ukunqanda ukukhulelwa ngexesha lonyango kunye ne-carfilzomib kunye neenyanga ezintathu emva kwethamo lakho lokugqibela. Ukuba wena okanye iqabane lakho nikhulelwe ngelixa nifumana amayeza, bizani ugqirha. UCarfilzomib unokulimaza umbungu.
• xelela ugqirha wakho ukuba uncelisa. Musa ukuncancisa ngelixa ufumana inaliti ye-carfilzomib kunye neeveki ezi-2 emva kwedosi yakho yokugqibela.
• Kuya kufuneka uyazi ukuba i-carfilzomib inokukwenza wozele, ube nesiyezi, okanye ube nentloko encinci, okanye ubangele ukuba utyhafe. Musa ukuqhuba okanye ukusebenzisa oomatshini de ube uyazi ukuba lukuchaphazela njani eli yeza.

Sela amanzi amaninzi ngaphambi nasemini yonke imihla xa unyangwa nge-carfilzomib, ngakumbi xa ugabha okanye urhuda.

Inaliti yeCarfilzomib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukudinwa
• intloko ebuhlungu
• ubuthathaka
• urhudo
• ukuqhina
• Ukudumba kwezihlunu
• iintlungu ezingalweni okanye emilenzeni

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu okanye ezo zidweliswe kumacandelo OKHUSELEKO NOKUQHELEKILEYO, tsalela ugqirha wakho:

• ukukhohlela
• umlomo owomileyo, umchamo omnyama, ukwehla kokubila, ulusu olomileyo, kunye neminye imiqondiso yokuphelelwa ngamanzi emzimbeni
• iingxaki zokuva
• ukudumba kweenyawo zemilenze
• intlungu, ukuthamba, okanye ubomvu kumlenze omnye
• ukuphefumla kancinci okanye ukuphefumla nzima
• iintlungu zesifuba
• iintlungu, ukutshisa, ukuba ndindisholo, okanye ukubetha ezandleni okanye ezinyaweni
• isicaphucaphu
• ukudinwa kakhulu
• ukopha okungaqhelekanga okanye ukugruzuka
• ukunqongophala kwamandla
• Ukuphelelwa ngumdla wokutya
• iintlungu kwinxalenye ephezulu yesisu
• mthubi ulusu okanye amehlo
• Iimpawu ezinjengomkhuhlane
• enegazi okanye emnyama, ilindle
• ukukhawuleza kwamabala abomvu obomvu-obomvu, ngokuqhelekileyo kwimilenze engezantsi
• igazi kumchamo
• ukuncipha kokuchama
• ukuxhuzula
• utshintsho lombono
• ubunzima bokulala okanye ukulala
• ukudideka, ukulahleka kwememori, isiyezi okanye ukulahleka kokulinganisela, ubunzima bokuthetha okanye ukuhamba, utshintsho kumbono, ukunciphisa amandla okanye ubuthathaka kwelinye icala lomzimba

Inaliti yeCarfilzomib inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• Ukugodola
• isiyezi
• ukuncipha kokuchama

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kujonga uxinzelelo lwegazi rhoqo kwaye ayalele iimvavanyo ezithile ukujonga impendulo yomzimba wakho kwi-carfilzomib.

Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nenaliti ye-carfilzomib.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• IKyprolis^®