Inaliti ye-Ado-trastuzumab Emtansine

Umxholo

• Ngaphambi kokufumana i-ado-trastuzumab emtansine,
• I-Ado-trastuzumab emtansine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:
• Iimpawu libanda kungaquka oku kulandelayo:

I-Ado-trastuzumab emtansine inokubangela iingxaki zesibindi okanye ezisongela ubomi. Tshela ugqirha wakho ukuba ukhe unesifo sesibindi, kubandakanya i-hepatitis. Ugqirha wakho uya kuyalela iimvavanyo zaselebhu rhoqo ngaphambi nangexesha lonyango lwakho ukubona ukuba ado-trastuzumab emtansine iyasichaphazela na isibindi sakho. Ugqirha wakho angakuxelela ukuba akufuneki ufumane eli yeza xa uvavanyo lubonisa ukuba unengxaki yesibindi. Xelela ugqirha wakho kunye nosokhemesti malunga nawo onke amayeza owathathayo ukuze bajonge ukuba nawaphi na amayeza akho anokuwonyusa umngcipheko wokuba uya kukhula umonakalo wesibindi ngexesha lonyango lwakho kunye ne-ado-trastuzumab emtansine. Tsalela umnxeba kwangoko ukuba unazo naziphi na kwezi mpawu zilandelayo: isicaphucaphu, ukugabha, ukudinwa kakhulu, ukungabikho kwamandla, ukungabi namdla, iintlungu kwinxalenye ephezulu yesisu, ukuba tyheli kolusu okanye amehlo, umchamo omnyama, Iimpawu ezinjengomkhuhlane, ukudideka, ukozela, okanye intetho engacacanga.

I-Ado-trastuzumab emtansine nayo inokubangela iingxaki zentliziyo okanye ezisongela ubomi. Tshela ugqirha wakho ukuba unesifo sentliziyo, isifo sentliziyo, iintlungu esifubeni, okanye ukubetha kwentliziyo okungaqhelekanga. Ugqirha wakho uya ku-odola uvavanyo ngaphambi nangexesha lonyango lwakho ukuze abone ukuba intliziyo yakho isebenza kakuhle ngokwaneleyo ukuze ufumane ngokukhuselekileyo i-ado-trastuzumab emtansine. Ugqirha wakho angakuxelela ukuba akufuneki ufumane eli yeza xa uvavanyo lubonisa ukubanakho kwentliziyo yakho yokupompa igazi. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko: khohlo; ukuqhawukelwa ngumphefumlo; ukudumba kweengalo, izandla, iinyawo, amaqatha okanye imilenze esezantsi; ukutyeba (ngaphezu kweepawundi ezi-5 [malunga neekhilogram eziyi-2.3] ngeyure ezingama-24); isiyezi; ukulahleka kwengqondo; okanye ukukhawuleza, ukungahambi kakuhle, okanye ukubetha kwentliziyo.

Tshela ugqirha wakho ukuba ukhulelwe okanye ukuba wena okanye iqabane lakho liceba ukukhulelwa. I-Ado-trastuzumab emtansine inokulimaza usana lwakho olungekazalwa. Ukuba unokukhulelwa, kuya kufuneka ukuba ube novavanyo lokukhulelwa olubi ngaphambi kokuba uqale unyango nge-ado-trastuzumab emtansine. Kuya kufuneka usebenzise ulawulo lokuzalwa ukuthintela ukukhulelwa ngexesha lonyango lwakho kunye neenyanga ezisixhenxe emva kwethamo lakho lokugqibela. Ukuba uyindoda kwaye iqabane lakho linokukhulelwa, kuya kufuneka usebenzise ulawulo lokuzalwa ngelixa ufumana eliyeza, kunye neenyanga ezi-4 emva kwedosi yakho yokugqibela. Thetha nogqirha wakho malunga neendlela zokulawula ukuzalwa eziza kukusebenzela. Ukuba wena okanye iqabane lakho ukhulelwe ngexesha lonyango lwakho kunye ne-ado-trastuzumab emtansine, tsalela ugqirha ngokukhawuleza.

Thetha nogqirha wakho malunga nemingcipheko yokufumana inaliti ye-ado-trastuzumab emtansine.

Inaliti ye-Ado-trastuzumab emtansine isetyenziselwa ukunyanga uhlobo oluthile lomhlaza wamabele osasazeke kwamanye amalungu omzimba kwaye awuzange uphuculwe okanye uye wanda emva konyango ngamanye amayeza. I-Ado-trastuzumab emtansine ikwasetyenziswa emva kotyando lohlobo oluthile lomhlaza wamabele kwabasetyhini abaye bafumana unyango ngamanye amayeza e-chemotherapy ngaphambi kotyando, kodwa bekukho umhlaza oseleyo kwizicubu ezisuswe ngexesha lotyando. I-Ado-trastuzumab emtansine ikwiklasi yamayeza abizwa ngokuba ngama-anti-drug conjugates. Isebenza ngokubulala iiseli zomhlaza.

Inaliti ye-Ado-trastuzumab emtansine iza njengomgubo wokudityaniswa nolwelo kwaye ifakwe (itofwe kancinci) emthanjeni ngugqirha okanye ngumongikazi esibhedlele okanye kwindawo yezonyango. Ihlala itofwe kanye kwiiveki ezintathu. Ubude bonyango lwakho buxhomekeke kwindlela ophendula ngayo emzimbeni wakho kunyango nakwiziphumo ebezingalindelekanga ohlangabezana nazo.

Inaliti ye-Ado-trastuzumab emtansine inokubangela iimpendulo ezinxulumene nokufakwa ngaphakathi, ezinokuthi zenzeke ngexesha okanye kungekudala emva kokufakwa kweyeza. Kuya kuthatha imizuzu engama-90 ukuba ufumane idosi yakho yokuqala ye-ado-trastuzumab emtansine. Ugqirha okanye umongikazi uya kukujonga ngokusondeleyo ukuze abone ukuba umzimba wakho uphendula njani kolu nyango. Ukuba awunangxaki zinzima xa ufumana idosi yakho yokuqala ye-ado-trastuzumab emtansine, kuya kuthatha imizuzu engama-30 ukuba ufumane idosi nganye eseleyo yonyango. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, xelela ugqirha ngoko nangoko: ukugungxula; ifiva; Ukugodola; isiyezi; intloko emhlophe; isiqaqa; ukuqhawukelwa ngumphefumlo; ubunzima bokuphefumla; okanye ukukhawuleza, ukungahambi kakuhle, okanye ukubetha kwentliziyo.

Ugqirha wakho unokufuna ukulibazisa unyango lwakho, ukunciphisa ukunyuswa, okanye ukuyeka unyango lwakho xa uneziphumo ezithile. Qiniseka ukuba uxelela ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho nge-ado-trastuzumab emtansine.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana i-ado-trastuzumab emtansine,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-ado-trastuzumab emtansine, i-trastuzumab, nawaphi na amanye amayeza, okanye naziphi na izithako kwi-ado-trastuzumab emtansine injection. Buza ugqirha wakho okanye usokhemesti uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qinisekisa ukukhankanya amayeza adweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO kunye nayo nayiphi na kwezi zilandelayo: apixaban (Eliquis), aspirin (Durlaza, eAgrenrenox, abanye), atazanavir (Reyataz, e-Evotaz), cilostazol (Pletal), clarithromycin (Biaxin, Kwi-Prevpac), clopidogrel (Plavix), dabigatran (Pradaxa), dalteparin (Fragmin), dipyridamole (Persantine, eAggrenox), edoxaban (Savaysa), enoxaparin (Lovenox), fondaparinux (Arixtra), heparin, indinaazonivole (Onmel, Sporanox), ketoconazole, nefazodone, nelfinavir (Viracept), prasugrel (Effient), ritonavir (Norvir, eKaletra, Technivie, Viekira Pak), rivaroxabanxaban (Xarelto), saquinavir (Invirase), telithromycin Brilinta), vorapaxar (iZontivity), voriconazole (Vfend), kunye ne-warfarin (Coumadin, Jantoven). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ungowenzala yaseAsia, okanye ukuba ukhe okanye wakha wanayo nayiphi na imiqathango ekhankanywe kwicandelo LESILUMKISO ESIBALULEKILEYO, unengxaki yokuphefumla, naxa uphumla, unyango ngemitha okanye nayiphi na imeko yezonyango.
• xelela ugqirha wakho ukuba uncelisa. Akufanelanga ukuncancisa ngelixa ufumana inaliti ye-ado-trastuzumab emtansine kunye neenyanga ezisixhenxe emva kwethamo lakho lokugqibela.

Thetha nogqirha wakho malunga nokutya igrapefruit kunye nokusela ijusi yamagilebhisi ngelixa ufumana lamayeza.

I-Ado-trastuzumab emtansine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukuqhina
• urhudo
• isisu esimoshakele
• izilonda emlonyeni nasemqaleni
• umlomo owomileyo
• utshintsho kubuchule bokungcamla
• intlungu edibeneyo okanye yemisipha
• intloko ebuhlungu
• owomileyo, obomvu, okanye iinyembezi
• ukungaboni kakuhle
• ingxaki yokulala okanye ukulala

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:

• iintlungu, ukurhawuzelela, ukuba bomvu, ukudumba, iblister, okanye izilonda kufutshane nalapho lalifakwe khona iyeza
• umkhuhlane, umqala obuhlungu, ingqele, ubunzima bokuchama, iintlungu xa uchama, kunye neminye imiqondiso yosulelo
• ukuphuma kweempumlo nokunye ukopha okungaqhelekanga okanye ukugruzuka
• enegazi okanye emnyama, ilindle
• ukugabha igazi okanye izinto ezimdaka ezifana namabala ekofu
• intlungu, ukutshisa, okanye ukubetha ezandleni nasezinyaweni, ubuthathaka bemisipha, ingxaki yokuhamba
• urhwebo
• irhashalala
• ukurhawuzelela
• ubunzima bokuphefumla okanye ukugwinya
• isicaphucaphu; ukugabha; ukuphelelwa ngumdla wokutya; ukudinwa; ukubetha kwentliziyo ngokukhawuleza; umchamo omnyama; ukunciphisa umchamo; isisu esibuhlungu; ukuxhuzula; ukubona izinto ezingekhoyo; okanye iicramps kunye ne-spasms
• ukuphefumla kancinci, ukukhohlela, ukudinwa kakhulu

I-Ado-trastuzumab emtansine inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• ukuphuma kweempumlo nokunye ukopha okungaqhelekanga okanye ukugruzuka
• enegazi okanye emnyama, ilindle
• ukugabha igazi okanye izinto ezimdaka ezifana namabala ekofu

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela uvavanyo lwelebhu ngaphambi kokuba uqale unyango lwakho ukuze ubone ukuba ngaba umhlaza wakho unganyangwa na nge-ado-trastuzumab emtansine.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• IKadcyla^®