Imvuliso

Umxholo

• Ngaphambi kokuba uthathe i-canagliflozin,
• Eli yeza linokubangela utshintsho kwiswekile yegazi lakho. Kuya kufuneka uyazi iimpawu zeswekile esezantsi kunye ephezulu yegazi kwaye wenzeni ukuba unayo le miqondiso.
• I-Canagliflozin inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:
• Ukuba ufumana naziphi na kwezi mpawu zilandelayo, yeka ukuthatha i-canagliflozin kwaye ubize ugqirha ngoko nangoko okanye ufumane unyango olungxamisekileyo:
• Ukuba ufumana naziphi na kwezi mpawu zilandelayo ze-ketoacidosis (imeko enzulu enokuthi ikhule ukuba iswekile ephezulu yegazi ayinyangwa), yeka ukuthatha i-canagliflozin kwaye ubize ugqirha ngokukhawuleza okanye ufumane unyango olukhawulezileyo. Ukuba kunokwenzeka, jonga ietoni kumchamo wakho ukuba unempawu, nokuba iswekile yegazi lakho ingaphantsi kwama-250 mg / dL:

I-Canagliflozin isetyenziswa kunye nokutya kunye nokuzilolonga, kwaye ngamanye amaxesha ngamanye amayeza, ukunciphisa amanqanaba eswekile yegazi kubantu abanesifo seswekile sesi-2 (imeko apho iswekile yegazi iphezulu kakhulu kuba umzimba awuvelisi okanye usebenzise i-insulin ngesiqhelo). I-Canagliflozin isetyenziselwa ukunciphisa umngcipheko wokubetha, ukuhlaselwa yintliziyo, okanye ukufa kubantu abane-2 yesifo sikashukela kunye nesifo senhliziyo nesifo segazi. I-Canagliflozin ikwasetyenziselwa ukunciphisa umngcipheko wesifo sezintso zokugqibela, ukwanda kokusebenza kwezintso, kufuna ukulaliswa esibhedlele ngenxa yokusilela kwentliziyo, kunye nokufa kwentliziyo yomntu kubantu abanesifo seswekile sesi-2 kunye nesifo sezintso. I-Canagliflozin ikudidi lwamayeza abizwa ngokuba yi-sodium-glucose co-transporter 2 (SGLT2) inhibitors. Yehlisa iswekile yegazi ngokubangela ukuba izintso zisuse iswekile eninzi kumchamo. ICanagliflozin ayisetyenziswanga ukunyanga uhlobo lweswekile yokuqala (imeko apho umzimba ungayivelisi khona i-insulin kwaye, ngenxa yoko, ayinakho ukulawula isixa seswekile esegazini).

Ixesha elingaphezulu, abantu abanesifo seswekile kunye neswekile ephezulu yegazi banokuba neengxaki ezinzulu okanye ezisongela ubomi, kubandakanya isifo sentliziyo, ukubetha, iingxaki zezintso, ukonakala kwemithambo-luvo kunye neengxaki zamehlo. Ukuthatha amayeza, ukwenza utshintsho kwindlela yokuphila (umzekelo, ukutya, ukwenza umthambo, ukuyeka ukutshaya), kunye nokujonga iswekile yegazi rhoqo kunokunceda ukulawula isifo seswekile kunye nokuphucula impilo yakho. Olu nyango lunokunciphisa amathuba akho okuhlaselwa sisifo sentliziyo, ukubetha, okanye ezinye iingxaki ezinxulumene nesifo seswekile ezinje ngokusilela kwezintso, ukulimala kwentliziyo (ukubindeka, imilenze ebandayo okanye iinyawo; ukunciphisa amandla ezesondo kumadoda nabasetyhini), iingxaki zamehlo, kubandakanya notshintsho okanye ukulahleka kombono, okanye isifo seentsini. Ugqirha wakho kunye nabanye ababoneleli ngempilo bayakuthetha nawe ngeyona ndlela yokulawula isifo sakho seswekile.

IKhanagliflozin iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kanye ngemini ngaphambi kwesidlo sakusasa okanye isidlo sokuqala esiphambili sosuku. Thatha i-canagliflozin malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-canagliflozin ngqo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ugqirha wakho unokukuqala kwidosi esezantsi yecanagliflozin kwaye ngokuthe ngcembe wandise idosi yakho.

ICanagliflozin ilawula uhlobo lweswekile yesibini kodwa ayisinyangi. Qhubeka uthathe i-canagliflozin nokuba uziva uphilile. Sukuyeka ukuthatha i-canagliflozin ngaphandle kokuthetha nogqirha wakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-canagliflozin,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba u-aleji (irhashalala, imihlathi, ukudumba kobuso bakho, imilebe, ulwimi, okanye umqala, okanye ukuphefumla nzima) kwi-canagliflozin, nawaphi na amanye amayeza, okanye naziphi na izithako ezikwiipilisi zecanagliflozin. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: i-angiotensin-converting enzyme (ACE) inhibitors enjenge benazepril (Lotensin, eLotrel), captopril, enalapril (Vasotec, in Vaseretic), fosinopril, lisinopril (in Zestoretic), moexipril (Univasc, Uniretic), perindopril (Aceon, in Prestalia), quinapril (Accupril, in Accuretic, in Quinaretic), ramipril (Altace), kunye netrandolapril (Mavik, eTarka); ii-angiotensin receptor blockers ezinje nge-azilsartan (Edarbi, e-Edarbyclor), candesartan (Atacand, e-Atacand HCT), eprosartan (Teveten), irbesartan (Avapro, eAvalide), losartan (Cozaar, e-Hyzaar), olmesartan (Benicar, e Azor, kwi-Benicar HCT, e-Tribenzor), telmisartan (Micardis, e Micardis HCT, e-Twynsta), nase-valsartan (Diovan, e-Diovan HCT, e-Exforge); idigoxin (Lanoxin); umchamo ('iipilisi zamanzi'); i-insulin; amanye amayeza eswekile; phenobarbital; phenytoin (iDilantin, iPhenytek); irifampin (Rifadin, Rimactane, eRifamate, eRifater); kunye ne-ritonavir (iNorvir, eKaletra). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba unedialysis. Ugqirha wakho unokukuxelela ukuba ungathathi i-canagliflozin.
• xelela ugqirha wakho ukuba uhlala usela utywala okanye ngamanye amaxesha usela izixa ezikhulu zotywala ngexesha elifutshane (ukuzinkcinkca ngotywala), okanye ukutya okune-sodium ephantsi. Kwakhona, xelela ugqirha wakho ukuba wakhe wanqunyulwa ilungu lomzimba, okanye wakha wanesifo sentliziyo, isifo semithambo (ukuncipha kwemithambo yegazi ezinyaweni, emilenzeni, okanye kwiingalo ezibangela ukuba ndindisholo, iintlungu, okanye ukubanda kuloo ndawo yomzimba), I-neuropathy (umonakalo wentsholongwane obangela ukurhawuzelela, ukuba ndindisholo, kunye nentlungu, zihlala zisezandleni nasezinyaweni), izilonda ezinyaweni okanye izilonda, uxinzelelo lwegazi oluphantsi, usulelo lomchamo, okanye iingxaki zomchamo, isifo sepancreatic kubandakanya ukudumba kwepancreas) Utyando olwenziwe kwi-pancreas, usulelo lwegwele kwindawo yesini, i-osteoporosis (imeko apho amathambo esiba buthathaka kwaye abuthathaka kwaye aphule ngokulula), isifo sezintso okanye sesibindi. Ukuba uyindoda, xelela ugqirha wakho ukuba awuzange waluswe. Tshela ugqirha wakho ukuba ngaba utya kancinci ngenxa yokugula, uqhaqho, okanye utshintsho kwindlela otya ngayo okanye ukuba awukwazi ukutya okanye ukusela ngesiqhelo ngenxa yokuba ubucaphucaphu, ukugabha, urhudo, okanye ukuba uphelelwe ngamanzi ngenxa yokuba selangeni .
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Musa ukuncancisa ngelixa uthatha i-canagliflozin. Ukuba ukhulelwa ngelixa uthatha i-canagliflozin, tsalela ugqirha wakho.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-canagliflozin.
• utywala kunokubangela utshintsho iswekile yegazi. Buza ugqirha wakho malunga nokusetyenziswa okukhuselekileyo kotywala ngelixa uthatha i-canagliflozin.
• Kuya kufuneka uyazi ukuba i-canagliflozin inokubangela ukuba ube nesiyezi, ukuba nentloko elula, kunye nokuphelelwa ngamandla xa usukuma ngokukhawuleza kwindawo oxokileyo kuyo. Ukuba unale ngxaki, tsalela umnxeba ugqirha wakho. Le ngxaki ixhaphake kakhulu xa uqala ukuthatha i-canagliflozin. Ukuthintela le ngxaki, phuma kancinci ebhedini, uphumle iinyawo zakho phantsi imizuzu embalwa ngaphambi kokuba ume.
• buza ugqirha wakho ukuba wenzeni ukuba uyagula, uhlasele usulelo okanye umkhuhlane, amava oxinzelelo angaqhelekanga, okanye wenzakele. Ezi meko zinokuchaphazela iswekile yegazi kunye nenani lecanagliflozin onokuyifuna.

Qiniseka ukuba ulandela yonke imithambo kunye nezincomo zokutya ezenziwe ngugqirha wakho okanye ugqirha otya ukutya. Kubalulekile ukutya ukutya okusempilweni nokuzilolonga rhoqo.

Landela imiyalelo kagqirha wakho malunga nokusela ngokwaneleyo ulwelo imini yonke ngelixa ukule nyango.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

Eli yeza linokubangela utshintsho kwiswekile yegazi lakho. Kuya kufuneka uyazi iimpawu zeswekile esezantsi kunye ephezulu yegazi kwaye wenzeni ukuba unayo le miqondiso.

I-Canagliflozin inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukuchama kakhulu, kubandakanya nasebusuku
• ukwanda kokoma
• ukuqhina
• umlomo owomileyo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

• Ukuchama rhoqo, okungxamisekileyo, okutshisayo, okanye okubuhlungu
• ukuncipha kwenani lomchamo
• umchamo onamafu, obomvu, opinki, okanye omdaka
• umchamo onukayo
• intlungu ye-pelvic okanye ye-rectal
• (kwabasetyhini) ivumba lobufazi, ukuphuma okumhlophe okanye okumthubi (kusenokuba namathambo okanye kujongeka njengekhitshi), okanye ukurhawuzelela kwilungu lobufazi
• (emadodeni) ukuba bomvu, ukurhawuzelela, okanye ukudumba kwelungu lobudoda; irhashalala kwilungu lobudoda; ukukhutshwa okungcolileyo kwilungu lobudoda; okanye iintlungu kulusu olujikeleze ipipi
• uziva udiniwe, ubuthathaka, okanye ungonwabanga; kunye nomkhuhlane kunye nentlungu, ukuthamba, ubomvu, kunye nokudumba kwamalungu esini okanye indawo phakathi kwamalungu esini kunye nethanga

Ukuba ufumana naziphi na kwezi mpawu zilandelayo, yeka ukuthatha i-canagliflozin kwaye ubize ugqirha ngoko nangoko okanye ufumane unyango olungxamisekileyo:

• irhashalala
• urhwebo
• ukurhawuzelela
• kunzima ukugwinya
• ukudumba kobuso, umqala, ulwimi, imilebe, umlomo, okanye amehlo
• ukudinwa

Ukuba ufumana naziphi na kwezi mpawu zilandelayo ze-ketoacidosis (imeko enzulu enokuthi ikhule ukuba iswekile ephezulu yegazi ayinyangwa), yeka ukuthatha i-canagliflozin kwaye ubize ugqirha ngokukhawuleza okanye ufumane unyango olukhawulezileyo. Ukuba kunokwenzeka, jonga ietoni kumchamo wakho ukuba unempawu, nokuba iswekile yegazi lakho ingaphantsi kwama-250 mg / dL:

• isicaphucaphu
• ukugabha
• indawo yesisu
• ukudinwa
• ubunzima bokuphefumla

Kuya kufuneka uyazi ukuba i-canagliflozin inokuwonyusa umngcipheko wokuba unqunyulwe umlenze (iinzwane, unyawo, okanye umlenze). Ugqirha wakho uza kukuxelela ukuba uyikhathalele njani imilenze kunye neenyawo zakho ngokufanelekileyo ukukhusela usulelo kunye neengxaki ezinokubangela ukuba unqunyulwe. Landela imiyalelo kagqirha ngononophelo kwaye ubize ugqirha wakho ngoko nangoko ukuba unayo nayiphi na intlungu, ukuthamba, izilonda, izilonda, okanye ukudumba, indawo efudumeleyo, ebomvu kwindawo yomlenze okanye unyawo, umkhuhlane okanye ingqele, okanye ezinye iimpawu kunye neempawu zosulelo.

I-Canagliflozin inokunyusa ithuba lokuqhekeka (ithambo elaphukileyo), ngakumbi kwiingalo ezingaphezulu, izihlahla, okanye izandla. Thetha nogqirha wakho malunga nemingcipheko yokuthatha la mayeza.

I-Canagliflozin inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya ku-odola uvavanyo lwelebhu ngaphambi kunye nangexesha lonyango lwakho nge-canagliflozin ukujonga ukuba zisebenza njani izintso zakho. Amanqanaba eswekile yegazi lakho kufuneka atshekishwe rhoqo ukumisela impendulo yakho kwi-canagliflozin. Ugqirha wakho uya ku-odola ezinye iimvavanyo zelebhu, kubandakanya ne-glycosylated hemoglobin (HbA1c), ukujonga impendulo yakho kwi-canagliflozin. Ugqirha wakho uya kukuxelela nendlela yokujonga impendulo yakho kolu nyango ngokulinganisa amanqanaba eswekile yegazi lakho ekhaya. Landela le miyalelo ngononophelo.

Ngaphambi kokuba uvavanywe elebhu, xelela ugqirha wakho kunye nabasebenzi baselebhu ukuba uthatha i-canagliflozin. Ngenxa yendlela la mayeza asebenza ngayo, umchamo wakho unokuvavanya ukuba une-glucose.

Kufuneka usoloko unxibe isacholo esichaza isifo seswekile ukuze uqiniseke ukuba ufumana unyango olufanelekileyo ngexesha likaxakeka.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Ingenokana^®

• I-Invokamet^® (iqulethe iCanagliflozin kunye neMetformin)