Afatinib

Umxholo

• Ngaphambi kokuba uthathe i-afatinib,
• I-Afatinib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, yeka ukuthatha i-afatinib kwaye ubize ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:
• Iimpawu zokudlula ngaphezulu zinokubandakanya:

I-Afatinib isetyenziselwa ukunyanga iintlobo ezithile zomhlaza wesifo semiphunga ongasasazekiyo osasazeke kwizicwili ezikufutshane okanye kwamanye amalungu omzimba. I-Afatinib ikudidi lwamayeza abizwa ngokuba yi-kinase inhibitors. Isebenza ngokuthintela isenzo sento ethile yendalo enokubakho enokufuneka ukunceda iiseli zomhlaza zande.

I-Afatinib iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa ngaphandle kwesisu kanye ngemini, ubuncinci iyure enye ngaphambi okanye iiyure ezi-2 emva kokutya okanye ukutya. Thatha i-afatinib malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-afatinib ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ugqirha wakho unokuyeka okwethutyana okanye ngokusisigxina unyango lwakho okanye unciphise idosi ukuba uneziphumo ebezingalindelekanga ezibi ze-afatinib. Thetha nogqirha wakho malunga nendlela oziva ngayo ngexesha lonyango lwakho.

Qhubeka uthathe i-afatinib nokuba uziva uphilile. Sukuyeka ukuthatha i-afatinib ungakhange uthethe nogqirha wakho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-afatinib,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-afatinib, nawaphi na amanye amayeza, okanye naziphi na izithako kwiipilisi ze-afatinib. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhalwanga, iivithamini, kunye nezongezelelo zesondlo ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: amiodarone (Cordarone, Pacerone); amayeza athile okubulala anje nge-itraconazole (Sporanox) kunye ne-ketoconazole (Nizoral); icyclosporine (Gengraf, Neoral, Sandimmune); erythromycin (EES, Erythrocin, abanye); amayeza athile kwintsholongwane (i-HIV) efana ne-nelfinavir (Viracept), i-ritonavir (i-Norvir, e-Kaletra), kunye ne-saquinavir (i-Invirase) amayeza athile okubanjwa afana ne-carbamazepine (Carbatrol, Equetro, Tegretol), phenobarbital, kunye ne phenytoin (Dilantin); quinidine (kwiNuedexta); irifampin (Rimactane, Rifadin, eRifater); itacrolimus (Prograf); Kunye neverapamil (Calan, Covera, Isoptin, Verelan). Uninzi lwamanye amayeza anokusebenzisana ne-afatinib, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
• xelela ugqirha wakho ukuba ungowenzala yaseAsia okanye ukhe wanengxaki yemiphunga okanye yokuphefumla (ngaphandle komhlaza wemiphunga); iingxaki zamehlo, kubandakanya namehlo owomileyo; iingxaki zentliziyo; isibindi okanye isifo sezintso; okanye nayiphi na imeko yezonyango. Kwakhona xelela ugqirha wakho ukuba unxiba iilensi zonxibelelwano.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Akufanele ukhulelwe ngelixa uthatha i-afatinib kwaye ubuncinci iiveki ezi-2 emva konyango lwakho. Thetha nogqirha wakho ngeendlela zolawulo lokuzalwa onokuzisebenzisa ngexesha lonyango lwakho. Ukuba ukhulelwa ngelixa uthatha i-afatinib, biza ugqirha wakho ngokukhawuleza. I-Afatinib inokulimaza umbungu.
• xelela ugqirha wakho ukuba uncelisa. Akufanelanga ukuncancisa ngelixa uthatha i-afatinib.
• cwangcisa ukuthintela ukukhanya elangeni ngokungeyomfuneko okanye ixesha elide kunye nokunxiba impahla ekhuselayo, iiglasi zelanga kunye nescreen selanga. I-Afatinib inokwenza ulusu lwakho lubuthathaka kwilanga. Ukubonakaliswa kukukhanya kwelanga kwandisa umngcipheko wokuba uya kuphuhlisa irhashalala okanye amabala ngexesha lonyango lwakho nge-afatinib.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba zingaphantsi kweeyure ezili-12 ngaphambi kokuba ucwangciselwe ukuthatha idosi yakho elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Afatinib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukuqhekeka okanye ukudumba kwemilebe okanye izilonda kwiikona zomlomo
• isikhumba esomileyo okanye ukurhawuzelela
• Ukuphelelwa ngumdla wokutya
• usulelo lwesikhonkwane
• induna
• ukuphuma kwempumlo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, yeka ukuthatha i-afatinib kwaye ubize ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• urhudo
• umlomo owomileyo, umchamo omnyama, ukwehla kokubila, ulusu olomileyo, kunye neminye imiqondiso yokuphelelwa ngamanzi emzimbeni
• ukuncipha kokuchama
• ukudumba kweengalo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• irhashalala
• iintlungu, ukuba bomvu, ukuxobuka, okanye ukudumba kolusu
• ubunzima bokuphefumla
• ukuqhawukelwa ngumphefumlo
• ukukhawuleza kwentliziyo, ukungahambi kakuhle, okanye ukubetha kwentliziyo
• ukukhawuleza ukutyeba
• ukukhohlela
• ifiva
• ukudinwa kakhulu
• iintlungu kwindawo ephezulu yesisu
• ukugruzuka okanye ukopha okungaqhelekanga
• isicaphucaphu
• ukugabha
• mthubi ulusu okanye amehlo
• umchamo omnyama
• ebomvu, idumbile, ibuhlungu, okanye iinyembezi
• Utshintsho olukhawulezileyo kumbono, kubandakanya umbono ophuthileyo
• uvakalelo ekukhanyeni

I-Afatinib inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nokukhanya, ubushushu obungaphaya, kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

• isicaphucaphu
• ukugabha
• ubuthathaka
• isiyezi
• intloko ebuhlungu
• isisu esibuhlungu

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-afatinib.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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