IPerampanel

Umxholo

• Ngaphambi kokuba uthathe i-perampanel,
• I-Perampanel inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kumacandelo esiXwayiso ESIBALULEKILEYO KUNYE NEENKQUBO EZIQHELEKILEYO, yeka ukuthatha i-perampanel kwaye ubize ugqirha wakho kwangoko okanye ufumane unyango olungxamisekileyo:
• Iimpawu libanda kungaquka oku kulandelayo:

Abantu abathathe i-perampanel baphuhlise utshintsho olunzulu okanye olusongela ubomi kwimpilo yabo yengqondo kunye nokuziphatha, ngakumbi ukwanda kobutshaba okanye ubundlongondlongo kwabanye. Tshela ugqirha wakho ukuba ukhe wanalo naluphi na uhlobo lokugula ngengqondo okanye indlela yokuziphatha enoburharha. Nangona kunjalo, kuya kufuneka uyazi ukuba kunokwenzeka ukuba uhlakulele olu tshintsho kwimpilo yengqondo kunye nokuziphatha ngelixa uthatha i-perampanel nokuba awuzange ube nangxaki kwimpilo yengqondo okanye indlela yokuziphatha ngaphambili. Wena, usapho lwakho, okanye umntu omkhathalelayo kufuneka ubize ugqirha wakho ngoko nangoko ukuba ufumana naluphi na utshintsho kwiimvakalelo, isimilo, okanye ubuntu ngexesha lonyango lwakho nge-perampanel okanye ukuya kuthi ga kwinyanga emva kokumisa unyango lwakho. Ugqirha wakho uya kuyibeka esweni impilo yakho yengqondo ngexesha lonyango lwakho nge-perampanel, ngakumbi xa uqala ukuthatha eli yeza kunye neliphi na ixesha apho idosi yakho itshintshiwe. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, biza ugqirha wakho kwangoko: ubundlongondlongo, ubutshaba, umsindo, ixhala, ukuba nochuku, isimilo esikrokrisayo okanye ukungathembeki, ukudideka, iingxaki zememori, kunye nokucinga ngokwenzakalisa okanye ukubulala abanye okanye ukugrogrisa okanye ukuzama ukwenza njalo. Ugqirha wakho unokunciphisa idosi okanye ayeke amayeza akho.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-perampanel kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-perampanel.

I-Perampanel isetyenziselwa ukunyanga iintlobo ezithile zokuthinjwa kokuqala (ukuxhuzula okubandakanya icandelo elinye lobuchopho) kubantu abadala nakubantwana abaneminyaka emi-4 ubudala nangaphezulu. Ikwasetyenziswa ngokudibeneyo namanye amayeza ukunyanga iintlobo ezithile zokubanjwa kwe-tonic-clonic yokuqala (eyayisaziwa ngokuba sisifo esikhulu; ukubanjwa okubandakanya umzimba wonke) kubantu abadala nakubantwana abaneminyaka eli-12 ubudala okanye ngaphezulu. I-Perampanel ikudidi lwamayeza abizwa ngokuba zii-anticonvulsants. Isebenza ngokunciphisa izinto ezingaqhelekanga zombane kwingqondo.

I-Perampanel iza njengecwecwe kwaye njengokumiswa (ulwelo) ukuthatha ngomlomo. Ihlala ithathwa kanye ngemini ngexesha lokulala. Thatha i-perampanel malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-perampanel ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Hlanganisa ukunqunyanyiswa kakuhle phambi kokusetyenziswa kokuxuba amayeza ngokulinganayo.

Ngalo lonke ixesha sebenzisa isirinji yomlomo (ngomlomo) yedosi eza nokumiswa kweperampanel ukulungiselela kunye nokulinganisa idosi yakho. Sukusebenzisa icephe ukulinganisa idosi yakho.

Ugqirha wakho uya kukuqala ngedosi esezantsi ye-perampanel kwaye ngokuthe ngcembe andise idosi yakho, hayi ngaphezulu kwesinye kanye ngeveki.

I-Perampanel inokuba ngumkhwa wokwenza. Musa ukuthatha idosi enkulu, yithathe rhoqo, okanye uthathe ixesha elide kunokuba umiselwe ngugqirha.

I-Perampanel inokukunceda ukulawula imeko yakho kodwa ayiyinyangi. Sukuyeka ukuthatha ipampamp ngaphandle kokuthetha nogqirha wakho. Ukuba ngequbuliso uyeka ukuthatha i-perampanel, ukubanjwa kwakho kunokuba mandundu. Ugqirha wakho uya kunciphisa umthamo wakho ngokuthe ngcembe.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-perampanel,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-perampanel, nawaphi na amanye amayeza, okanye naziphi na izithako kwiipilisi ze-perampanel okanye ukumiswa ngomlomo. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo nolungabhaliswanga, iivithamini, kunye nezongezelelo zesondlo ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: i-barbiturates efana ne-phenobarbital kunye ne-secobarbital (Seconal); amayeza e-allergies, unxunguphalo, ukukhohlela kunye nokubanda, ukugula ngengqondo, kunye nentlungu; amayeza okubanjwa njenge carbamazepine (Carbatrol, Tegretol, Equetro), oxcarbazepine (Trileptal, Oxtellar), phenytoin (Dilantin, Phenytek), primidone (Mysoline), kunye ne topiramate (Topamax); irifampin (Rifadin); ukuthomalalisa; iipilisi zokulala; kunye noxinzelelo. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana ne-perampanel, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• Kuya kufuneka uyazi ukuba i-perampanel inokunciphisa ukusebenza kwezicwangcisi zehomoni (iipilisi zolawulo lokuzalwa, iipatches, iiringi, okanye izinto zokufakelwa) eziqukethe i-levonorgestrel. Sebenzisa enye indlela yolawulo lokuzalwa ngelixa uthatha i-perampanel kunye nenyanga e-1 emva kwedosi yakho yokugqibela. Buza ugqirha wakho okanye usokhemesti ukuba awuqinisekanga ukuba ulawulo lwakho lokuzalwa luqulathe i-levonorgestrel.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
• xelela ugqirha wakho ukuba uyasela okanye wakha wasela izixa ezikhulu zotywala, ukuba usebenzisa okanye wakha wasebenzisa iziyobisi ezitalatweni, okanye ukuba uye wawasebenzisa kakhulu amayeza kagqirha. Xelela ugqirha wakho ukuba ukhe unesifo sezintso okanye sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwe ngelixa uthatha i-perampanel, biza ugqirha wakho.
• Kuya kufuneka uyazi ukuba i-perampanel inokubangela isiyezi, ukozela, kunye neengxaki ngokulungelelanisa kunye nokulingana. Oku kunokunyusa umngcipheko wokuwa okunokubangela ukonzakala okukhulu, ngakumbi ukuba ukhulile. Musa ukuqhuba imoto, ukusebenzisa oomatshini, okanye ukuthatha inxaxheba kwimisebenzi efuna ukuphapha okanye ukulungelelanisa de ube uyazi ukuba lonyango lukuchaphazela njani.
• buza ugqirha wakho malunga nokusetyenziswa okukhuselekileyo kotywala ngelixa uthatha i-perampanel. Utywala bunokwenza iziphumo ebezingalindelekanga zibi ngakumbi.
• Kuya kufuneka uyazi ukuba impilo yakho yengqondo inokutshintsha ngeendlela ezingalindelekanga kwaye ungazibulala (ucinga ngokuzenzakalisa okanye ukuzibulala okanye ukucwangcisa okanye ukuzama ukwenza njalo) ngelixa uthatha i-perampanel. Inani elincinci labantu abadala kunye nabantwana abaneminyaka emi-5 ubudala nangaphezulu (malunga ne-1 kubantu abangama-500) abathathe i-anticonvulsants njenge-perampanel ukunyanga iimeko ezahlukeneyo ngexesha lezifundo zeklinikhi bazibulala ngexesha lonyango lwabo. Abanye baba bantu bakhulise iingcinga zokuzibulala kunye nokuziphatha kwiveki e-1 emva kokuba beqalisile ukuthatha amayeza. Kukho umngcipheko wokuba unokufumana utshintsho kwimpilo yakho yengqondo ukuba uthatha amayeza e-anticonvulsant anje nge-perampanel, kodwa kusenokubakho umngcipheko wokuba uya kuba neenguqu kwimpilo yakho yengqondo ukuba imeko yakho ayinyangwa. Wena kunye nogqirha wakho niya kuthatha isigqibo sokuba ngaba ingozi yokuthatha iyeza le-anticonvulsant inkulu kuneengozi zokungawasebenzisi amayeza. Wena, usapho lwakho, okanye umntu omkhathalelayo kufuneka ubize ugqirha wakho ngoko nangoko ukuba unazo naziphi na kwezi mpawu zilandelayo: uloyiko; ukuphazamiseka okanye ukungazinzi; okutsha okanye ukuhla kokucaphuka, uxinzelelo, okanye uxinzelelo; ukwenza izinto eziyingozi; ubunzima bokulala okanye ukulala; ndlongondlongo, umsindo okanye ubundlobongela; i-mania (i-frenzied, i-mood engaqhelekanga) ukuthetha okanye ukucinga ngokufuna ukuzenzakalisa okanye ukuzibulala; okanye naluphi na olunye utshintsho olungaqhelekanga kwindlela oziphethe ngayo okanye kwimood. Qiniseka ukuba usapho lwakho okanye umntu okhathalelayo uyazi ukuba zeziphi iimpawu ezinokuba nobuzaza ukuze babize ugqirha ukuba awukwazi ukuzifunela unyango ngokwakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yokulinganisa Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo. Ukuba uphosa ngaphezulu kwedosi enye, nxibelelana nogqirha wakho.

I-Perampanel inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isiyezi okanye ukujikeleza
• ukozela
• ukuqhina
• isicaphucaphu
• ukugabha
• intloko ebuhlungu
• ukudinwa
• ukutyeba kwakho
• ukucaphuka
• ubuthathaka
• iingxaki ngokulungelelanisa
• izihlunu, umqolo, okanye iintlungu ezidibeneyo
• ukuncipha kwengqondo yokuthinta okanye imvakalelo
• ukungaboni kakuhle okanye umbono ophindwe kabini

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kumacandelo esiXwayiso ESIBALULEKILEYO KUNYE NEENKQUBO EZIQHELEKILEYO, yeka ukuthatha i-perampanel kwaye ubize ugqirha wakho kwangoko okanye ufumane unyango olungxamisekileyo:

• irhashalala; imihlathi umkhuhlane okanye amadlala adumbileyo; ukudumba kobuso bakho okanye imilenze; ukuqhawukelwa ngumphefumlo; mthubi ulusu okanye amehlo; okanye umchamo omnyama

I-Perampanel inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Musa ukumisa umkhenkce ukunqunyanyiswa. Lahla nakuphi na ukumiswa okungasetyenziswanga kwiintsuku ezingama-90 emva kokuqala ukuvula ibhotile.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• isiyezi
• utshintsho olungaqhelekanga kwindlela oziphethe ngayo okanye kwiimvakalelo
• ukuphazamiseka
• Ukuziphatha gwenxa

Gcina lonke ixesha lokudibana nogqirha wakho.

Musa ukuvumela nabani na ukuba athathe amayeza akho. I-Perampanel yinto elawulwayo. Imigqaliselo inokugcwaliswa kuphela linani eliqingqiweyo lamaxesha; buza usokhemesti wakho ukuba unayo nayiphi na imibuzo.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Fycompa^®