Isofosbuvir

Umxholo

• Ngaphambi kokuba uthathe i-sofosbuvir,
• I-Sofosbuvir inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:

Usenokuba bosulelwe yi-hepatitis B (intsholongwane esosulela isibindi kwaye inokubangela ukonakala kwesibindi) kodwa ungabinazo iimpawu zesifo. Kule meko, ukuthatha i-sofosbuvir kunokunyusa umngcipheko wokuba ube neempawu kwaye usulelo lwakho luya kuba lukhulu okanye lusongele ubomi. Tshela ugqirha wakho ukuba ukhe wosulelwa yintsholongwane ye-hepatitis B. Ugqirha wakho uya ku-odola uvavanyo lwegazi ukuze abone ukuba ukhe wosuleleka sisifo se-hepatitis B. Ugqirha wakho uya kukujonga esweni usulelo lwe-hepatitis B ngexesha kunye neenyanga ezimbalwa emva konyango lwakho. Ukuba kukho imfuneko, ugqirha unokukunika amayeza ukunyanga olu sulelo ngaphambi nangexesha lonyango lwakho nge-sofosbuvir. Ukuba unazo naziphi na kwezi mpawu zilandelayo ngexesha okanye emva konyango lwakho, tsalela umnxeba kwangoko: ukudinwa okugqithisileyo, ukutyheli kwesikhumba okanye amehlo, ukuphelelwa ngumdla, isicaphucaphu, ukugabha, izitulo eziluthuthu, iintlungu esiswini, okanye umchamo omnyama.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho angayalela iimvavanyo ezithile ngaphambi, ngexesha, nasemva konyango lwakho ukujonga impendulo yomzimba wakho kwi-sofosbuvir.

Thetha nogqirha wakho malunga nomngcipheko (s) wokuthatha i-sofosbuvir.

I-Sofosbuvir isetyenziswa kunye ne-ribavirin (Copegus, Rebetol, Ribasphere, others) kwaye ngamanye amaxesha elinye iyeza (peginterferon alfa [Pegasys]) ukunyanga iintlobo ezithile ze-hepatitis C engapheliyo (usulelo lwentsholongwane oluqhubekayo olonakalisa isibindi) kubantu abadala. I-Sofosbuvir ikwasetyenziswa kunye ne-ribavirin ukunyanga iintlobo ezithile ze-hepatitis C engapheliyo (usulelo lwentsholongwane oluqhubekayo olonakalisa isibindi) kubantwana abaneminyaka emi-3 ubudala nangaphezulu. I-Sofosbuvir ikudidi lwamayeza antiviral abizwa ngokuba yi-nucleotide polymerase inhibitors. Isebenza ngokunciphisa inani le-virus ye-hepatitis C (HCV) emzimbeni. I-Sofosbuvir ayinako ukuthintela ukusasazeka kwe-hepatitis C kwabanye abantu.

I-Sofosbuvir iza njengecwecwe kunye neepelethi ukuba zithathe ngomlomo. Ihlala ithathwa kunye okanye ngaphandle kokutya kube kanye ngemini. Thatha i-sofosbuvir malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-sofosbuvir ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Iipellets zeSofosbuvir zingaginywa (ngaphandle kokuhlafuna) okanye zingathathwa kunye nokutya. Ukulungiselela idosi yeepellets ze-sofosbuvir ngokutya, tshiza yonke ipakethi yeepellets kwityhefu enye okanye engaphezulu yokubanda okanye igumbi lobushushu lokutya okungekho asidi okune-pudding, isiraphu yetshokholethi, iitapile ezicujiweyo, okanye ice cream. Thatha wonke umxube kwisithuba semizuzu engama-30 yokufefa iipellethi ekutyeni. Ukuthintela ukungcamla okukrakra, sukuzihlafuna iipellets.

Qhubeka nokuthatha i-sofosbuvir nokuba uziva uphilile. I-Sofosbuvir kufuneka ithathwe ngokudibanisa ne-peginterferon alfa kunye ne-ribavirin okanye ngokudibanisa ne-ribavirin yodwa. Ukuba i-sofosbuvir ithathwa ngokudibanisa ne-peginterferon alfa kunye ne-ribavirin, ihlala ithathwa iiveki ezili-12. Ukuba i-sofosbuvir ithathwa ngokudibanisa ne-ribavirin iyodwa, ihlala ithathwa iiveki ezili-12 okanye ezingama-24. Ukuba unomhlaza wesibindi kwaye ulinde ukufakelwa kwesibindi, uya kuthatha i-sofosbuvir kunye ne-ribavirin ukuya kwiiveki ezingama-48 okanye de ube ufakelwa isibindi. Ubude bonyango lwakho buxhomekeke kwimeko yakho, ukuba uphendula njani kunyango, kwaye nokuba uneziphumo ebezingalindelekanga ezibi. Ungayeki ukuthatha i-sofosbuvir, i-peginterferon alfa, okanye i-ribavirin, ngaphandle kokuba uxelelwe ngugqirha ukuba wenze njalo.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-sofosbuvir,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana nesofosbuvir, nawaphi na amanye amayeza, okanye naziphi na izithako ezikwiipilisi zeesofosbuvir okanye iipellets. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo nolungabhaliswanga, iivithamini, kunye nezongezelelo zesondlo ozithathayo okanye oceba ukuzithatha. Qinisekisa ukukhankanya nayiphi na kwezi zilandelayo: amiodarone (Nexterone, Pacerone); amayeza athile omhlaza; amayeza seswekile; amayeza athile okubanjwa afana ne-carbamazepine (Carbatrol, Epitol, Equetro, Tegretol), oxcarbazepine (Trileptal), phenobarbital, okanye phenytoin (Dilantin, Phenytek); amayeza athile acinezela amajoni omzimba; irifabutin (Mycobutin); irifampin (Rifadin, Rimactane, eRifamate, eRifater); irifapentine (Priftin); i-tipranavir (Aptivus) kunye ne-ritonavir (i-Norvir); kunye ne-warfarin (Coumadin, Jantoven). Ugqirha wakho unokukuxelela ukuba ungathathi i-sofosbuvir ukuba uthatha elinye okanye ngaphezulu kwala mayeza okanye ukujonga ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-sofosbuvir, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort. Akufanele uthathe i-wort yaseSt.John ngexesha lonyango lwakho nge-sofosbuvir.
• xelela ugqirha wakho ukuba ukhe wafakelwa isibindi okanye ukuba unayo okanye wakha wanayo intsholongwane kaGawulayo (i-HIV), naluphi na uhlobo lwesifo sesibindi ngaphandle kwe-hepatitis C, isifo sezintso, okanye kwi-dialysis.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye unokukhulelwa. Ukuba uyindoda, xelela ugqirha wakho ukuba iqabane lakho likhulelwe, liceba ukukhulelwa, okanye kunokwenzeka ukuba ukhulelwe. I-Sofosbuvir kufuneka ithathwe nge-ribavirin enokonakalisa kakhulu usana olungekazalwa. Kuya kufuneka usebenzise iindlela ezimbini zolawulo lokuzalwa ukukhusela ukukhulelwa kuwe okanye kwiqabane lakho ngexesha lonyango ngala mayeza kunye neenyanga ezi-6 emva konyango lwakho. Thetha nogqirha wakho malunga neendlela onokuzisebenzisa; izinto zokucwangcisa zehomoni (iipilisi zolawulo lokuzalwa, iziqwengana, izinto zokufakelwa, imisesane, okanye inaliti) zisenokungasebenzi kakuhle kwabasetyhini abathatha la mayeza. Wena okanye iqabane lakho kufuneka nivavanyelwe ukukhulelwa ngaphambi konyango, inyanga nenyanga ngexesha lonyango, kunye neenyanga ezi-6 emva konyango lwakho. Ukuba wena okanye iqabane lakho ukhulelwe ngelixa uthatha la mayeza okanye kwiinyanga ezi-6 emva konyango, biza ugqirha ngokukhawuleza.
• xelela ugqirha wakho ukuba uncelisa.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Ukuba ukhumbula idosi ephosiweyo ngomhla obumele ukuba wawuthatha, thatha idosi ephosiweyo kwakamsinya nje emva kokuba uyikhumbule ngalo mhla. Nangona kunjalo, ukuba awukhumbuli idosi ephosiweyo kude kube lusuku olulandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yedosi. Musa ukuthatha amanani amabini ngosuku olunye.

I-Sofosbuvir inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• urhudo
• intloko ebuhlungu
• iintlungu zemisipha
• ubunzima bokulala okanye ukulala
• ukucaphuka
• ukurhawuzelela
• irhashalala

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:

• ulusu oluthuthu
• isiyezi
• ukuqhawukelwa ngumphefumlo
• ubuthathaka
• umqala obuhlungu, umkhuhlane, ukubanda, kunye neminye imiqondiso yosulelo
• irhashalala, kunye okanye ngaphandle kwamadyunguza
• ukudumba kobuso, umqala, ulwimi, imilebe, amehlo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• ukudinwa
• ubunzima bokuginya okanye ukuphefumla

I-Sofosbuvir inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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