Empagliflozin

Umxholo

• Ngaphambi kokuba uthathe i-empagliflozin,
• Eli yeza linokubangela utshintsho kwiswekile yegazi lakho. Kuya kufuneka uyazi iimpawu zeswekile esezantsi kunye ephezulu yegazi kwaye wenzeni ukuba unayo le miqondiso.
• I-Empagliflozin inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:
• Ukuba unazo naziphi na kwezi mpawu zilandelayo, yeka ukuthatha impagliflozin kwaye ubize ugqirha ngoko nangoko okanye ufumane unyango olungxamisekileyo:
• Ukuba ufumana naziphi na kwezi mpawu zilandelayo ze-ketoacidosis, yeka ukuthatha i-empagliflozin kwaye ubize ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo. Ukuba kunokwenzeka, jonga ietoni kumchamo wakho ukuba unempawu, nokuba iswekile yegazi lakho ingaphantsi kwama-250 mg / dL:

I-Empagliflozin isetyenziswa kunye nokutya kunye nokuzilolonga, kwaye ngamanye amaxesha namanye amayeza, ukunciphisa iswekile yegazi kubantu abanesifo seswekile sesi-2 (imeko apho iswekile esegazini iphezulu kakhulu kuba umzimba awuvelisi okanye usebenzise i-insulin ngesiqhelo). I-Empagliflozin ikwasetyenziselwa ukunciphisa umngcipheko wokubetha, isifo sentliziyo, okanye ukufa kubantu abane-2 yeswekile kunye nentliziyo kunye nesifo semithambo yegazi. Ikwiklasi yamayeza abizwa ngokuba yi-sodium-glucose co-transporter 2 (SGLT2) inhibitors. I-Empagliflozin yehlisa iswekile yegazi ngokubangela ukuba izintso zisuse iswekile eninzi kumchamo. Ayisetyenziselwa ukunyanga uhlobo lwe-1 yeswekile (imeko apho umzimba ungayivelisi i-insulin kwaye, ngenxa yoko, awunakho ukulawula ubungakanani beswekile egazini) okanye isifo seswekile ketoacidosis (imeko enzulu enokuthi ikhule ukuba iswekile ephezulu yegazi ayinyangwa. ).

Ixesha elingaphezulu, abantu abanesifo seswekile kunye neswekile ephezulu yegazi banokuba neengxaki ezinzulu okanye ezisongela ubomi, kubandakanya isifo sentliziyo, ukubetha, iingxaki zezintso, ukonakala kwemithambo-luvo kunye neengxaki zamehlo. Ukuthatha amayeza, ukwenza utshintsho kwindlela yokuphila (umzekelo, ukutya, ukwenza umthambo, ukuyeka ukutshaya), kunye nokujonga iswekile yegazi rhoqo kunokunceda ukulawula isifo seswekile kunye nokuphucula impilo yakho. Olu nyango lunokunciphisa amathuba akho okuhlaselwa sisifo sentliziyo, ukubetha, okanye ezinye iingxaki ezinxulumene nesifo seswekile ezinje ngokusilela kwezintso, ukulimala kwentliziyo (ukubindeka, imilenze ebandayo okanye iinyawo; ukunciphisa amandla ezesondo kumadoda nabasetyhini), iingxaki zamehlo, kubandakanya notshintsho okanye ukulahleka kombono, okanye isifo seentsini. Ugqirha wakho kunye nabanye ababoneleli ngempilo bayakuthetha nawe ngeyona ndlela yokulawula isifo sakho seswekile.

I-Empagliflozin iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kanye ngemini kusasa kunye okanye ngaphandle kokutya. Thatha i-empagliflozin malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-empagliflozin ngqo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ugqirha wakho unokukuqala kwidosi esezantsi ye-empagliflozin kwaye wandise idosi yakho njengoko kufuneka.

I-Empagliflozin ilawula uhlobo lwe-2 yeswekile kodwa ayiyinyangi. Qhubeka nokuthatha impagliflozin nokuba uziva uphilile. Sukuyeka ukuthatha impagliflozin ngaphandle kokuthetha nogqirha wakho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-empagliflozin,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-empagliflozin, nawaphi na amanye amayeza, okanye naziphi na izithako kwiipilisi ze-empagliflozin. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: i-angiotensin-converting enzyme (ACE) inhibitors enjenge benazepril (Lotensin, eLotrel), captopril, enalapril (Vasotec, in Vaseretic), fosinopril, lisinopril (in Zestoretic), moexipril (Univasc, Uniretic), perindopril (Aceon, in Prestalia), quinapril (Accupril, in Accuretic, in Quinaretic), ramipril (Altace), kunye netrandolapril (Mavik, eTarka); ii-angiotensin receptor blockers ezinje nge-azilsartan (Edarbi, e-Edarbyclor), candesartan (Atacand, e-Atacand HCT), eprosartan (Teveten), irbesartan (Avapro, eAvalide), losartan (Cozaar, e-Hyzaar), olmesartan (Benicar, e Azor, kwi-Benicar HCT, e-Tribenzor), telmisartan (Micardis, e Micardis HCT, e-Twynsta), nase-valsartan (Diovan, e-Diovan HCT, e-Exforge); i-aspirin kunye nezinye iyeza ezichasayo (i-NSAIDs) ezinje nge-ibuprofen (Advil, Motrin) kunye ne-naproxen (Aleve, Naprosyn); idigoxin (Lanoxin); umchamo ('iipilisi zamanzi'); okanye i-insulin okanye amayeza omlomo weswekile afana ne-chlorpropamide (i-Diabinese), i-glimepiride (i-Amaryl, kwi-Duetact), i-glipizide (i-Glucotrol), i-glyburide (i-DiaBeta, i-Glynase, kwi-Glucovance), i-tolazamide kunye ne-tolbutamide. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba unedialysis kwaye ukhe unesifo sezintso. Ugqirha wakho unokukuxelela ukuba ungathathi impagliflozin.
• xelela ugqirha wakho ukuba uhlala usela utywala okanye ngamanye amaxesha usela izixa ezikhulu zotywala ngexesha elifutshane (ukuzinkcinkca ngotywala) okanye kukutya okune-sodium. Kwakhona xelela ugqirha wakho ukuba ukhe wosuleleka kumchamo okanye uneengxaki zokuchama, uxinzelelo lwegazi oluphantsi, i-cholesterol ephezulu, ukusilela kwentliziyo, isifo se-pancreatic kubandakanya ne-pancreatitis (ukudumba kwepancreas) okanye uqhaqho kwi-pancreas yakho, usulelo lwegwele kwindawo yesini, okanye isifo sesibindi. Ukuba uyindoda, xelela ugqirha wakho ukuba awuzange waluswe. Tshela ugqirha wakho ukuba ngaba utya kancinci ngenxa yokugula, uqhaqho, okanye utshintsho kwindlela otya ngayo okanye ukuba awukwazi ukutya okanye ukusela ngesiqhelo ngenxa yokuba ubucaphucaphu, ukugabha, urhudo, okanye ukuba uphelelwe ngamanzi ngenxa yokuba selangeni .
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Musa ukuncancisa ngelixa uthatha i-empagliflozin. Ukuba ukhulelwa ngelixa uthatha i-empagliflozin, tsalela ugqirha wakho.
• ukuba uyenziwa utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha impagliflozin.
• utywala kunokubangela utshintsho iswekile yegazi. Buza ugqirha wakho malunga nokusetyenziswa okukhuselekileyo kotywala ngelixa uthatha i-canagliflozin.
• Kuya kufuneka uyazi ukuba i-empagliflozin inokubangela ukuba ube nesiyezi, ukuba nentloko elula, kunye nokuphelelwa ngamandla xa usukuma ngokukhawuleza kwindawo oxokileyo kuyo. Ukuba unale ngxaki, tsalela umnxeba ugqirha wakho. Le ngxaki ixhaphake kakhulu xa uqala ukuthatha i-empagliflozin. Ukuthintela le ngxaki, phuma kancinci ebhedini, uphumle iinyawo zakho phantsi imizuzu embalwa ngaphambi kokuba ume
• buza ugqirha wakho ukuba wenzeni ukuba uyagula, uhlasele usulelo okanye umkhuhlane, amava oxinzelelo angaqhelekanga, okanye wenzakele. Ezi meko zinokuchaphazela iswekile yegazi lakho kunye nenani le-empagliflozin onokuyifuna.

Qiniseka ukuba ulandela yonke imithambo kunye nezincomo zokutya ezenziwe ngugqirha wakho okanye ugqirha otya ukutya. Kubalulekile ukutya ukutya okusempilweni nokuzilolonga rhoqo. Landela imiyalelo kagqirha wakho malunga nokusela ngokwaneleyo ulwelo imini yonke ngelixa ukule nyango.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

Eli yeza linokubangela utshintsho kwiswekile yegazi lakho. Kuya kufuneka uyazi iimpawu zeswekile esezantsi kunye ephezulu yegazi kwaye wenzeni ukuba unayo le miqondiso.

I-Empagliflozin inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukuchama kakhulu, kubandakanya nasebusuku
• ukwanda kokoma

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

• Ukuchama rhoqo, okungxamisekileyo, okutshisayo, okanye okubuhlungu
• umchamo onamafu, obomvu, opinki, okanye omdaka
• iintlungu zangasemva okanye zangasemva
• (kwabasetyhini) ivumba lobufazi, ukuphuma okumhlophe okanye okumthubi (kusenokuba namathambo okanye kujongeka njengekhitshi), okanye ukurhawuzelela kwilungu lobufazi
• (emadodeni) ukuba bomvu, ukurhawuzelela, okanye ukudumba kwelungu lobudoda; irhashalala kwilungu lobudoda; ukukhutshwa okungcolileyo kwilungu lobudoda; okanye iintlungu kulusu olujikeleze ipipi
• uziva udiniwe, ubuthathaka, okanye ungonwabanga; kunye nomkhuhlane kunye nentlungu, ukuthamba, ubomvu, kunye nokudumba kwamalungu esini okanye indawo phakathi kwamalungu esini kunye nethanga
• Iimpawu ezinjengomkhuhlane

Ukuba unazo naziphi na kwezi mpawu zilandelayo, yeka ukuthatha impagliflozin kwaye ubize ugqirha ngoko nangoko okanye ufumane unyango olungxamisekileyo:

• irhashalala
• urhwebo
• ukurhawuzelela
• ubunzima bokuginya okanye ukuphefumla
• ukudumba kobuso, umqala, ulwimi, imilebe, umlomo, okanye amehlo
• ukudinwa

Ukuba ufumana naziphi na kwezi mpawu zilandelayo ze-ketoacidosis, yeka ukuthatha i-empagliflozin kwaye ubize ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo. Ukuba kunokwenzeka, jonga ietoni kumchamo wakho ukuba unempawu, nokuba iswekile yegazi lakho ingaphantsi kwama-250 mg / dL:

• isicaphucaphu
• ukugabha
• indawo yesisu
• ukudinwa
• ubunzima bokuphefumla

I-Empagliflozin inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Amanqanaba eswekile yegazi lakho kufuneka atshekishwe rhoqo ukumisela impendulo yakho kwi-empagliflozin. Ugqirha wakho uya kuyalela ezinye iimvavanyo zelebhu, kubandakanya i-hemoglobin ye-glycosylated (HbA1c), ukujonga impendulo yakho kwi-empagliflozin. Ugqirha wakho uya kukuxelela nendlela yokujonga impendulo yakho kolu nyango ngokulinganisa amanqanaba eswekile yegazi lakho ekhaya. Landela le miyalelo ngononophelo.

Ngaphambi kokuba uvavanywe elebhu, xelela ugqirha wakho kunye nabasebenzi baselebhu ukuba uthatha impagliflozin. Ngenxa yendlela la mayeza asebenza ngayo, umchamo wakho unokuvavanya ukuba une-glucose.

Kufuneka usoloko unxibe isacholo esichaza isifo seswekile ukuze uqiniseke ukuba ufumana unyango olufanelekileyo ngexesha likaxakeka.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Intlanganisela^®
• UGlyxambi^® (njengemveliso yokudibanisa equlethe i-Empagliflozin kunye neLinagliptin)
• Ungqinelwano^® (njengemveliso yokudibanisa equlethe i-Empagliflozin kunye neMetformin)