ILedipasvir kunye neSofosbuvir

Umxholo

• Ngaphambi kokuba uthathe i-ledipasvir kunye ne-sofosbuvir,
• I-Ledipasvir kunye ne-sofosbuvir zinokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

Usenokuba bosulelwe yi-hepatitis B (intsholongwane esosulela isibindi kwaye inokubangela ukonakala kwesibindi), kodwa ungabinazo iimpawu zesi sifo. Kule meko, ukuthatha indibaniselwano ye-ledipasvir kunye ne-sofosbuvir kunokunyusa umngcipheko wokuba uya kuba neempawu kwaye usulelo lwakho luya kuba lukhulu okanye lusongele ubomi Xelela ugqirha wakho ukuba ukhe wosulelwa yintsholongwane ye-hepatitis B. Ugqirha wakho uya ku-odola uvavanyo lwegazi ukuze abone ukuba unesifo bosulelo lwe-hepatitis B. Ugqirha wakho uya kukujonga esweni usulelo lwe-hepatitis B ngexesha kunye neenyanga ezimbalwa emva konyango lwakho. Ukuba kukho imfuneko, ugqirha unokukunika amayeza ukunyanga olu sulelo ngaphambi nangexesha lonyango lwakho ngokudityaniswa kwe-ledipasvir kunye ne-sofosbuvir. Ukuba unazo naziphi na kwezi mpawu zilandelayo ngexesha okanye emva konyango lwakho, tsalela umnxeba kwangoko: ukudinwa okugqithisileyo, ukutyheli kwesikhumba okanye amehlo, ukuphelelwa ngumdla, isicaphucaphu, ukugabha, izitulo eziluthuthu, iintlungu esiswini, okanye umchamo omnyama.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho angayalela iimvavanyo ezithile ngaphambi, ngexesha, nasemva konyango lwakho ukujonga impendulo yomzimba wakho kwindibaniselwano ye-ledipasvir kunye ne-sofosbuvir.

Thetha nogqirha wakho malunga nomngcipheko (s) wokuthatha indibaniselwano yeedipasvir kunye nesofosbuvir.

Indibaniselwano ye-ledipasvir kunye ne-sofosbuvir isetyenziswa yodwa okanye idityaniswe ne-ribavirin (Copegus, Rebetol, Ribasphere, others) ukunyanga iintlobo ezithile ze-hepatitis C engapheliyo (usulelo lwentsholongwane oluqhubekayo olonakalisa isibindi) kubantu abadala nakubantwana abaneminyaka emi-3 ubudala kunye mdala. I-Sofosbuvir ikudidi lwamayeza antiviral abizwa ngokuba yi-nucleotide polymerase inhibitors. Isebenza ngokunciphisa inani le-virus ye-hepatitis C (HCV) emzimbeni. ILedipasvir ikudidi lwamayeza antiviral abizwa ngokuba yi-HCV NS5A inhibitors. Isebenza ngokumisa intsholongwane ebangela i-hepatitis C ukuba isasazeke emzimbeni.

Indibaniselwano yeedipasvir kunye nesofosbuvir iza njengecwecwe kunye neepellets zokuzithatha ngomlomo. Ihlala ithathwa kunye okanye ngaphandle kokutya kube kanye yonke imihla. Thatha i-ledipasvir kunye ne-sofosbuvir ngexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-ledipasvir kunye ne-sofosbuvir ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

ILedipasvir kunye ne-sofosbuvir pellets zingaginywa (ngaphandle kokuhlafuna) okanye zingathathwa kunye nokutya. Ukulungiselela idosi yeedipasvir kunye neesofosbuvir ipellets ngokutya, tshiza yonke ipakethi yeepellets kwityhefu enye okanye engaphezulu yokubanda okanye ubushushu begumbi ukutya okungekho asidi okunee-pudding, isiraphu yetshokholethi, iitapile ezicujiweyo, okanye ice cream. Thatha wonke umxube kwisithuba semizuzu engama-30 yokufefa iipellethi ekutyeni. Ukuthintela ukungcamla okukrakra, sukuzihlafuna iipellets.

Qhubeka uthathe i-ledipasvir kunye ne-sofosbuvir nokuba uziva uphilile. Ubude bonyango lwakho (iiveki eziyi-8 ukuya kwezi-24) kuxhomekeke kwimeko yakho, ukuba uphendula njani kunyango, nokuba ngaba uneziphumo ebezingalindelekanga ezibi. Sukuyeka ukuthatha i-ledipasvir kunye ne-sofosbuvir ngaphandle kokuthetha nogqirha wakho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-ledipasvir kunye ne-sofosbuvir,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-ledipasvir okanye i-sofosbuvir, nawaphi na amanye amayeza, okanye naziphi na izithako ezikwi-ledipasvir kunye neepilisi ze-sofosbuvir okanye iipellets. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo nolungabhaliswanga, iivithamini, kunye nezongezelelo zesondlo ozithathayo okanye oceba ukuzithatha. Qinisekisa ukukhankanya nayiphi na kwezi zilandelayo: amiodarone (Nexterone, Pacerone); idigoxin (Lanoxin); amayeza athile omhlaza; amayeza seswekile; amayeza athile okubanjwa afana ne-carbamazepine (Carbatrol, Epitol, Equetro, Tegretol), oxcarbazepine (Oxtellar XR, Trileptal), phenobarbital, okanye phenytoin (Dilantin, Phenytek); amayeza okutshisa kunye nezilonda; amayeza e-HIV athathwe kunye afana ne-efavirenz (Sustiva, e-Atripla), emtricitabine (Emtriva, e-Atripla) kunye ne-tenofovir (Viread, e-Atripla); elvitegravir (Sustiva, e-Atripla), cobicistat (Tybost, eStribild), emtricitabine (Emtriva, eSribild), kunye ne-tenofovir (Viread, e-Stribild); i-tenofovir (Viread), atazanavir (Reyataz) kunye ne-ritonavir (Norvir); i-tenofovir (iViread), i-darunavir (i-Prezista) kunye ne-ritonavir (i-Norvir); i-tenofovir (Viread), lopinavir (eKaletra), kunye ne-ritonavir (Norvir, eKaletra); okanye i-tipranavir (Aptivus) kunye ne-ritonavir (Norvir); amayeza athile acinezela amajoni omzimba; irifabutin (Mycobutin); irifampin (Rifadin, Rimactane, eRifamate, eRifater); irifapentine (Priftin); irosuvastatin (Crestor); isimeprevir (iOlysio); isofosbuvir (Sovaldi); kunye ne-warfarin (Coumadin, Jantoven). Ugqirha wakho unokukuxelela ukuba ungathathi i-ledipasvir kunye ne-sofosbuvir ukuba uthatha elinye okanye ngaphezulu kwala mayeza okanye unokukujonga ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana ne-ledipasvir kunye ne-sofosbuvir, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• ukuba uthatha ii-antacids ezine-aluminium hydroxide okanye i-magnesium hydroxide (Maalox, Mylanta, Tums, others), thatha iiyure ezi-4 ngaphambi okanye kwiiyure ezi-4 emva kokuthatha i-ledipasvir kunye ne-sofosbuvir.
• xelela ugqirha wakho ukuba uthatha amayeza okugaya isisu, ukutsha kwentliziyo, okanye izilonda (H₂ blockers) ezinje ngecimetidine, ranitidine (Zantac), famotidine (Pepcid, in Duexis) okanye nizatidine. Ugqirha wakho angakuxelela ukuba ubathathe iiyure ezili-12 phambi okanye iiyure ezili-12 emva kwe-ledipasvir kunye ne-sofosbuvir, okanye kwangaxeshanye uthatha i-ledipasvir kunye ne-sofosbuvir.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort. Akufanele uthathe i-wort yaseSt. John ngexesha lokunyanga kwakho nge-ledipasvir kunye ne-sofosbuvir.
• xelela ugqirha wakho ukuba ukhe wafakelwa isibindi okanye ukuba unayo intsholongwane kaGawulayo. Kwakhona xelela ugqirha wakho ukuba ukhe wanalo naluphi na uhlobo lwesifo sesibindi ngaphandle kwe-hepatitis C, isifo sezintso, okanye kwi-dialysis.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-ledipasvir kunye ne-sofosbuvir, biza ugqirha wakho. Ukuba i-ledipasvir kunye ne-sofosbuvir zisetyenziswa ngokudibeneyo ne-ribavirin, qiniseka ukuba ufunda ulwazi malunga nokukhulelwa kokukhusela kwi-ribavirin monograph.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Ledipasvir kunye ne-sofosbuvir zinokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukudinwa
• intloko ebuhlungu
• ubunzima bokulala okanye ukulala
• isicaphucaphu
• urhudo
• ukukhohlela
• isiyezi
• iintlungu zemisipha
• ukucaphuka

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

• irhashalala
• amadyungudyungu
• ukudumba kobuso, iingalo, okanye imilenze
• ukuqhawukelwa ngumphefumlo
• ukudinwa
• ubunzima bokuginya okanye ukuphefumla

I-Ledipasvir kunye ne-sofosbuvir zinokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Sukusebenzisa ukuba itywina ngaphezulu kokuvulwa kwebhotile lophukile okanye lilahlekile. Yigcine kubushushu begumbi kwaye kude nokukhanya, ubushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• IHarvoni^®