UNintedanib

Umxholo

• Ngaphambi kokuba uthathe i-nintedanib,
• I-Nintedanib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

I-Nintedanib isetyenziselwa ukunyanga i-idiopathic pulmonary fibrosis (IPF; scarring of the lungs with a unknown cause). Isetyenziselwa ukunyanga iintlobo ezithile zezifo zemiphunga ezingapheliyo (i-ILD; isifo esiqhubekayo apho kukho ukwanda kwemiphunga). I-Nintedanib ikwasetyenziselwa ukunciphisa isantya sokwehla kokusebenza kwemiphunga kubantu abane-systemic sclerosis-ehambelana nesifo sangaphakathi semiphunga (i-SSc-ILD; ekwabizwa ngokuba yi-scleroderma-ehambelana ne-ILD: sisifo apho kukho ukonakala kwemiphunga edla ngokubulala ). U-Nintedanib ukwiklasi yamayeza abizwa ngokuba yi-kinase inhibitors. Isebenza ngokuthintela isenzo se-enzymes ezichaphazelekayo ekubangeleni i-fibrosis.

UNintedanib uza njengephilisi emayithathwe ngomlomo. Ihlala ithathwa ngokutya rhoqo kwiiyure ezili-12 (kabini ngemini). Thatha iipilisi ze-nintedanib ngamaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-nintedanib ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Gwinya zonke njengezingxobo kulwelo; sukuzihlafuna okanye uzityumze.

Ugqirha wakho unokufuna ukunciphisa idosi okanye ayeke unyango ukuba uneziphumo ebezingalindelekanga. Qiniseka ukuba uxelela ugqirha wakho indlela oziva ngayo ngexesha lonyango lwakho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-nintedanib,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-nintedanib, nawaphi na amanye amayeza, okanye naziphi na izithako kwiifomsile ze-nintedanib. Buza usokhemesti wakho okanye ujonge ulwazi lomenzi wesigulana uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo nolungabhaliswanga, iivithamini, kunye nezongezelelo zesondlo ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: ii-anticoagulants ('' blood thinner '') ezifana ne-warfarin (Coumadin, Jantoven); i-aspirin kunye nezinye iziyobisi ezichasayo (i-NSAIDS) ezifana ne-ibuprofen (Advil, Motrin, abanye) kunye ne-naproxen (Aleve, Anaprox, Naprelan); icarbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril); I-erythromycin (i-EES, i-Ery-Tab, i-Eryc); ketoconazole; laxatives; i-steroids yomlomo efana ne-dexamethasone (i-Decadron, i-Dexpak), i-methylprednisolone (Medrol) kunye ne-prednisone; phenytoin (iDilantin, iPhenytek); ipirfenidone (Esbriet); irifampin (Rifadin, Rimactane, eRifamate, eRifater); okanye ezithambisa isitulo. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
• xelela ugqirha wakho ukuba wena okanye omnye umntu kusapho lwakho ukhe wanengxaki yokopha, ukuba unesifo sesibindi okanye sentliziyo, isifo esingafaniyo (i-diverticulitis; iipokotshi ezincinci kumngxunya wamathumbu amakhulu anokudumba), okanye amahlwili egazi, kwaye ukuba ukhe wenza utyando lwesisu kutshanje.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye unokukhulelwa. Akufanele uqale ukuthatha i-nintedanib de uvavanyo lokukhulelwa lubonise ukuba awukhulelwe. Akufanele ukhulelwe ngelixa uthatha i-nintedanib; amayeza angalimaza usana lwakho olungekazalwa. I-Nintedanib inokunciphisa ukusebenza kwezicwangcisi zehomoni (iipilisi zolawulo lokuzalwa, iipatches, iiringi, izinto zokufakelwa, okanye inaliti), ngenxa yoko akufuneki uzisebenzise njengeyona ndlela yakho yolawulo lokuzalwa. Kuya kufuneka usebenzise indlela yothintelo lolawulo lokuzalwa (isixhobo esivimba isidoda ukuba singene esibelekweni esifana nekhondom okanye uvalo). Thetha nogqirha wakho malunga neendlela zolawulo lokuzalwa onokuzisebenzisa ngexesha lonyango lwakho kwaye ubuncinci iinyanga ezi-3 emva kwedosi yakho yokugqibela ye-nintedanib. Ukuba ukhulelwa ngelixa uthatha i-nintedanib, biza ugqirha wakho ngokukhawuleza.
• xelela ugqirha wakho ukuba uncelisa.
• xelela ugqirha wakho ukuba usebenzisa iimveliso zecuba. Ukutshaya icuba kunokunciphisa ukusebenza kweli yeza. Kuya kufuneka uyeke ukutshaya ngaphambi kokuba uqale ukuthatha i-nintedanib kwaye uphephe ukutshaya ngexesha lonyango lwakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Ukuba uphosa idosi ye-nintedanib, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Nintedanib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• ukunciphisa ukutya
• ukuhla ukusinda

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• urhudo
• ukudinwa kakhulu
• ukopha okungaqhelekanga okanye ukugruzuka
• ukunqongophala kwamandla
• Ukuphelelwa ngumdla wokutya
• iintlungu kwinxalenye ephezulu yesisu
• mthubi ulusu okanye amehlo
• umchamo omnyama okanye omdaka (umbala weti)
• iintlungu zesifuba
• iintlungu ezingalweni, emqolo, entanyeni, okanye emhlathini
• ukuqhawukelwa ngumphefumlo
• Ukuba ndindisholo okanye ubuthathaka kwelinye icala lomzimba wakho
• kunzima ukuthetha
• intloko ebuhlungu
• isiyezi
• amanxeba angapholiyo
• iintlungu okanye ukudumba kwindawo yakho yesisu, isicaphucaphu, ukugabha, umkhuhlane, ukugodola, okanye igazi kwigumbi lakho lokugcina
• irhashalala
• ukurhawuzelela

I-Nintedanib inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ngaphambi nangexesha lonyango lwakho ukujonga impendulo yomzimba wakho kwi-nintedanib.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Ofev^®