Unyango

Umxholo

• Ngaphambi kokuthatha i-sonidegib,
• I-Sonidegib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu, yeka ukuthatha i-sonidegib kwaye ubize ugqirha ngokukhawuleza:

Zonke izigulana:

I-Sonidegib akufuneki ithathwe ngabafazi abakhulelweyo okanye abanokukhulelwa. Kukho umngcipheko omkhulu wokuba i-sonidegib ibangele ukulahleka kokukhulelwa okanye ibangele ukuba umntwana azalwe enesiphene sokuzalwa (iingxaki zomzimba ezikhoyo ekuzalweni).

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-sonidegib kwaye ngalo lonke ixesha uzalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye undwendwele iwebhusayithi yomenzi ukufumana isiKhokelo seMithi

Musa ukunikela ngegazi okanye iimveliso zegazi ngelixa uthatha i-sonidegib kwaye ubuncinci iinyanga ezingama-20 emva konyango lwakho.

Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-sonidegib.

Kwabaguli ababhinqileyo:

Ukuba unokukhulelwa, kuya kufuneka unqande ukukhulelwa ngexesha lonyango lwakho kunye ne-sonidegib. Kuya kufuneka uvavanyo lokukhulelwa olungelulo ngaphambi kokuqala konyango lwakho. Kuya kufuneka usebenzise iindlela ezamkelekileyo zolawulo lokuzalwa ngexesha lonyango lwakho kwaye ubuncinci iinyanga ezingama-20 emva kokuba ligqityiwe unyango lwakho. Ugqirha wakho uya kukuxelela ukuba zeziphi iindlela zolawulo lokuzalwa ezamkelekileyo.

Ukuba ucinga ukuba ukhulelwe, uphoswe kukuya exesheni, okanye ukuba neentlobano zesini ngaphandle kolawulo lokuzalwa ngelixa uthatha i-sonidegib okanye kwiinyanga ezingama-20 emva konyango, biza ugqirha ngoko nangoko.

Kwizigulana ezingamadoda:

Kuya kufuneka usebenzise ikhondom, nokuba unayo ivasectomy (utyando ukunqanda isidoda ukuba singaphumi emzimbeni wakho kwaye sibangele ukukhulelwa), ngalo lonke ixesha usabelana ngesondo nomntu obhinqileyo okhulelweyo okanye okwaziyo ukukhulelwa ngelixa uthatha i-sonidegib kwaye kangangeenyanga ezisibhozo emva konyango lwakho. Xelela ugqirha wakho kwangoko ukuba uye walala ngesondo ngokungakhuselekanga nomntu wasetyhini onokukhulelwa okanye ukuba ucinga ngaso nasiphi na isizathu ukuba iqabane lakho likhulelwe. Sukunikela ngamadlozi ngelixa uthatha i-sonidegib okanye kwiinyanga ezisi-8 emva konyango lwakho.

I-Sonidegib isetyenziselwa ukunyanga i-basal cell carcinoma (BCC; uhlobo lomhlaza wolusu) kubantu abadala abanomhlaza obuyileyo emva kotyando okanye ngemitha, okanye kubantu abadala abanganyangekiyo ngotyando okanye ngemitha. I-Sonidegib ikudidi lwamayeza abizwa ngokuba yi-hedgehog pathway inhibitors. Isebenza ngokuthintela isenzo seprotini ebonisa iiseli zomhlaza ukuba zande. Oku kunceda ukumisa okanye ukucothisa ukusasazeka kweeseli zomhlaza kwaye kunokunceda ukuncipha amathumba.

I-Sonidegib iza njengepilisi yokuthatha ngomlomo. Ihlala ithathwa kanye ngemini kwisisu esingenanto, ubuncinci iyure enye ngaphambi okanye iiyure ezi-2 emva kwesidlo. Thatha i-sonidegib malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-sonidegib ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ugqirha wakho unokufuna ukuphazamisa okanye ayeke unyango lwakho kuxhomekeke kwimpendulo yakho kwi-sonidegib kunye naziphi na iziphumo ebezingalindelekanga ohlangabezana nazo.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuthatha i-sonidegib,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-sonidegib, nawaphi na amanye amayeza, okanye naziphi na izithako kwiifomsile ze-sonidegib. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhalwanga, iivithamini kunye nezongezo zesondlo ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: atazanavir (Reyataz); ii-antifungals ezithile ezinjenge fluconazole (Diflucan), itraconazole (Onmel, Sporanox), ketoconazole, posaconazole (Noxafil), kunye ne voriconazole (Vfend); diltiazem (Cardizem, Cartia, Tiazac, nabanye); efavirenz (Sustiva, eAtripla); imodafinil (Provigil); nefazodone; irifabutin (Mycobutin); irifampin (Rifadin, Rifamate, Rifater, Rimactane); i-saquinavir (i-Invirase); amayeza athile okubanjwa afana ne-carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril), phenobarbital, kunye ne phenytoin (Dilantin, Phenytek); kunye ne-telithromycin (Ketek). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-sonidegib, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort. Ugqirha wakho uya kukuxelela ukuba ungathathi i-wort yase-St John ngelixa uthatha i-sonidegib.
• xelela ugqirha wakho ukuba ukhe unesifo semisipha.
• xelela ugqirha wakho ukuba uncelisa. Ugqirha wakho unokukuxelela ukuba ungancancisi ngelixa uthatha i-sonidegib kunye neenyanga ezingama-20 emva konyango lwakho.

Thetha nogqirha wakho malunga nokutya igrapefruit kunye nokusela ijusi yamagilebhisi ngelixa uthatha eli yeza.

Tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yokulinganisa Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Sonidegib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• urhudo
• intlungu zesisu
• Ukuphelelwa ngumdla wokutya
• ukuhla ukusinda
• isicaphucaphu
• ukugabha
• utshintsho kwisakhono sokungcamla ukutya
• ukulahleka kweenwele
• ukurhawuzelela
• ubuthathaka
• ukudinwa kakhulu
• intlungu
• ukuphoswa lixesha lokuya exesheni

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu, yeka ukuthatha i-sonidegib kwaye ubize ugqirha ngokukhawuleza:

• ukudumba kwezihlunu
• Iintlungu zemisipha ezingachazwanga, ukuthamba okanye ubuthathaka
• umchamo omnyama okanye wecola
• ukuncipha kokuchama
• ukungakwazi ukuchama

I-Sonidegib inokunciphisa ukuzala kwabasetyhini. Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-sonidegib ukuba unenkxalabo malunga nokuzala.

I-Sonidegib inokubangela ukukhula kuyeke kwangethuba ebantwaneni. Eli yeza akukhuthazwa ukuba lisetyenziswe ebantwaneni.

I-Sonidegib inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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