I-Eluxadoline

Umxholo

• Ngaphambi kokuba uthathe i-eluxadoline,
• I-Eluxadoline inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, yeka ukuthatha i-eluxadoline kwaye ubize ugqirha ngoko nangoko okanye ufumane unyango olungxamisekileyo:

I-Eluxadoline isetyenziselwa ukunyanga isisu esirhabaxa ngesifo sorhudo (IBS-D; imeko ebangela iintlungu zesisu, ukubamba, okanye ukungcola okanye isitulo esinamanzi) kubantu abadala. I-Eluxadoline ikudidi lwamayeza abizwa ngokuba yi-mu-opioid receptor agonists.Isebenza ngokunciphisa umsebenzi wamathumbu.

I-Eluxadoline iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa ngokutya kabini imihla ngemihla. Thatha i-eluxadoline kumaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-eluxadoline ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

I-Eluxadoline inokuba ngumkhwa wokwenza umkhwa. Musa ukuthatha idosi enkulu, yithathe rhoqo, okanye uthathe ixesha elide kunokuba umiselwe ngugqirha.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-eluxadoline,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabana ne-eluxadoline, nawaphi na amanye amayeza, okanye naziphi na izithako ezikwiipilisi ze-eluxadoline. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: alfentanil (Alfenta); alosetron (iLotronex); ii-antibiotics ezifana ne-ciprofloxacin (Cipro) kunye ne-clarithromycin (i-Biaxin, kwi-Prevpac); amayeza anticholinergic anjenge benztropine (Cogentin), dicyclomine (Bentyl), diphenhydramine (Benadryl); bupropion (Forfivo XL, Wellbutrin, Zyban, nabanye); I-eltrombopag (iPractacta); amayeza ohlobo lwe-ergot anjenge-dihydroergotamine (i-DHE 45, iMigranal) kunye ne-ergotamine tartrate (i-Ergomar, eCafergot, eMigergot); fentanyl (Abstral, Actiq, Duragesic, Sublimaze, nabanye); i-fluconazole (iDiflucan); gemfibrozil (iLopid); amayeza e-HIV afana ne-atazanavir (Reyataz, e-Evotaz), lopinavir (Kaletra), ritonavir (Norvir, e-Kaletra, e-Viekira Pak), i-saquinavir (i-Invirase), kunye ne-tipranavir (Aptivus); amayeza athintela amajoni omzimba anje ngecyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), kunye netacrolimus (Astagraf, Envarsus XR, Prograf); i-opiate (narcotic) amayeza entlungu; paroxetine (Brisdelle, Paxil, Pexeva); ipimozide (Orap); quinidine (kwiNuedexta); irifampin (Rifadin, Rimactane, eRifamate, eRifater); Kunye nerosuvastatin (Crestor). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• Kuya kufuneka uyazi ukuba ungathatha i-loperamide (Imodium AD) ngamanye amaxesha ukunyanga isifo sohudo ngelixa uthatha i-eluxadoline. Yeka ukuthatha i-loperamide kwangoko ukuba uyaqhinwa.
• xelela ugqirha wakho ukuba unengxaki yokuqunjelwa ngoku okanye ukuba uhlala unengxaki yokuqhinwa, ukuba uyasela okanye wakha wasela izixa ezikhulu zotywala (ngaphezulu kwezi-3 iziselo ezinxilisayo ngosuku), okanye ukuba awunayo i-gallbladder. Xelela ugqirha wakho ukuba unayo okanye wakha wanengxaki yokuthintela inyongo (ukuvalwa kwimibhobho ethwala inyongo ukusuka kwisibindi ukuya kwi-gallbladder kunye namathumbu amancinci), i-sphincter ye-Oddi dysfunction (ukuvaleka kwenyongo okanye incindi yokugaya engena emathunjini ebangela intlungu okanye i-jaundice), ukuvaleka emathunjini akho, i-pancreatitis (ukudumba kwepancreas okungapheliyo), okanye isifo sesibindi. Ugqirha wakho uya kukuxelela ukuba ungathathi i-eluxadoline.
• xelela ugqirha wakho ukuba ukhe unesifo sezintso.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-eluxadoline, tsalela umnxeba ugqirha wakho.
• Kuya kufuneka uyazi ukuba i-eluxadoline inokukwenza wozele, ngakumbi ukuba unesifo sesibindi. Musa ukuqhuba imoto okanye usebenzise oomatshini de ube uyazi indlela elikuchaphazela ngayo eli yeza.
• xelela ugqirha wakho ukuba uhlala usela utywala okanye ngamanye amaxesha usela izixa ezikhulu zotywala ngexesha elifutshane. Buza ugqirha wakho malunga nokusetyenziswa okukhuselekileyo kotywala ngelixa uthatha i-eluxadoline. Ukusela utywala kunokunyusa umngcipheko wokuba ube nepancreatitis.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule ngokutya. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Eluxadoline inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, yeka ukuthatha i-eluxadoline kwaye ubize ugqirha ngoko nangoko okanye ufumane unyango olungxamisekileyo:

• iintlungu eziqala kwindawo ephezulu yesisu kodwa zinokusasazeka ngasemva okanye egxalabeni kunye okanye ngaphandle kwesicefecefe nokugabha
• ukuqhina okunzima
• irhashalala; imihlathi ubuso obudumbileyo okanye umqala; ukuqhawukelwa ngumphefumlo; ukuqina komqala; iintlungu zesifuba okanye ukuqina; okanye kunzima ukugwinya okanye ukuphefumla

I-Eluxadoline inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho.

Musa ukuvumela nabani na ukuba athathe amayeza akho. I-Eluxadoline yinto elawulwayo. Imigqaliselo inokugcwaliswa kuphela linani eliqingqiweyo lamaxesha; buza usokhemesti wakho ukuba unayo nayiphi na imibuzo.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• IViberzi^®