Inaliti yeMepolizumab

Umxholo

• Ngaphambi kokufumana inaliti ye-mepolizumab,
• Inaliti yeMepolizumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LOKUKHUSELEKILEYO OKUQHELEKILEYO, tsalela ugqirha wakho ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

Inaliti yeMepolizumab isetyenziswa kunye namanye amayeza ukuthintela ukuvutha, ukuphefumla nzima, ukuqina kwesifuba, kunye nokukhohlela okubangelwa sisifuba kubantwana abathile abaneminyaka emi-6 ubudala nangaphezulu kunye nabantu abadala abanesifuba esingalawulekiyo ngamayeza abo esi sifo. Isetyenziselwa ukunyanga i-eosinophilic granulomatosis nge-polyangiitis (i-EGPA; imeko ebandakanya isifuba, amanqanaba aphezulu eeseli ezimhlophe zegazi, kunye nokudumba kwenqanawa yegazi) kubantu abadala. Inaliti yeMepolizumab ikwasetyenziselwa ukunyanga isifo sehypereosinophilic (HES; iqela lokuphazamiseka kwegazi okwenzeka ngamanqanaba aphezulu eeseli ezimhlophe zegazi) kubantu abadala nakubantwana abaneminyaka eli-12 nangaphezulu abanayo le meko iinyanga ezi-6 okanye ngaphezulu. Inaliti yeMepolizumab ikudidi lwamayeza abizwa ngokuba ngamachiza omzimba. Isebenza ngokuthintela isenzo sento ethile yendalo emzimbeni ebangela iimpawu zesifuba.

Inaliti yeMepolizumab iza njengesirinji ekhethiweyo, i-autoinjector ekhethiweyo, okanye njengempuphu exutywe namanzi kunye nokujova ngenaliti (ngaphantsi nje kwesikhumba). Ihlala inikwa kube kanye kwiiveki ezi-4. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Sebenzisa inaliti ye-mepolizumab kanye njengoko kuyalelwe. Musa ukuyitofa ngaphezulu okanye ngaphantsi okanye uyitofe rhoqo kunokuba umiselwe ngugqirha. Ugqirha wakho uya kugqiba ubude bonyango lwakho ngokusekwe kwimeko yakho kunye nendlela ophendula ngayo kunyango.

Unokufumana idosi yakho yokuqala yenaliti ye-mepolizumab kwiofisi kagqirha wakho. Emva koko, ugqirha wakho unokukuvumela okanye umnakekeli ukuba anike inaliti ekhaya. Ngaphambi kokuba usebenzise inaliti ye-mepolizumab ngokwakho okokuqala, funda ulwazi lomenzi wesigulana esiza nonyango. Buza ugqirha wakho okanye usokhemesti akubonise okanye umntu oza kunika amayeza ukuba angatofa njani.

Sebenzisa isirinji nganye okanye i-autoinjector kube kanye kwaye ujove sonke isisombululo kwisirinji okanye kwi-autoinjector. Lahla iisirinji ezisetyenzisiweyo okanye ii-autoinjectors kwisitya esinganyangekiyo. Thetha nogqirha wakho okanye usokhemesti malunga nokusilahla isikhongozeli esinganyangekiyo.

Susa isirinji okanye i-autoinjector efrijini. Yibeke endaweni ethe tyaba ngaphandle kokuyisusa ikepusi yenaliti kwaye uyivumele ifudumele kubushushu begumbi kangangemizuzu engama-30 (hayi ngaphezulu kweeyure ezisi-8) phambi kokuba ulungele ukutofa iyeza. Sukuzama ukufudumeza amayeza ngokuwatshisa kwimicrowave, ngokuwabeka emanzini ashushu, uwashiye elangeni, okanye ngayo nayiphi na enye indlela.

Musa ukushukumisa isirinji equlethe i-mepolizumab.

Ukuba usebenzisa i-mepolizumab kwaye une-asthma, qhubeka nokuthatha okanye usebenzise onke amanye amayeza agunyaziswe ngugqirha wakho ukunyanga isifuba sakho. Sukunciphisa idosi yakho yalo naliphi na iyeza lesifuba okanye uyeke ukuthatha naliphi na iyeza elimiselweyo ngugqirha wakho ngaphandle kokuba ugqirha wakho ukuxelele ukuba wenze njalo. Ugqirha wakho unokufuna ukunciphisa amayeza akho amayeza ngokuthe ngcembe.

Soloko ujonga isisombululo se-mepolizumab ngaphambi kokuyifaka. Jonga ukuba umhla wokuphelelwa kwawo awudlulanga na kwaye ulwelo lucacile kwaye alunambala okanye tyheli kancinane ukuba mdaka kancinci. Umbane awunakuba namasuntswana abonakalayo. Sukusebenzisa isirinji efriziwe okanye ukuba ulwelo lunamafu okanye luqulathe amasuntswana amancinci.

Ungatofa inaliti ye-mepolizumab naphina phambi kwamathanga akho (umlenze ongasentla) okanye isisu (isisu) ngaphandle kwenkaba yakho kunye nendawo eyi-intshi ezimbini (iisentimitha ezi-5) ngeenxa zonke. Ukuba umnonopheli utofa iyeza, umva wengalo ephezulu unokusetyenziswa. Ukunciphisa amathuba okuqaqamba okanye ububomvu, sebenzisa indawo eyahlukileyo yenaliti nganye. Musa ukujova kwindawo apho ulusu luthambile, lutyumkileyo, lubomvu, okanye lukhuni okanye apho uneziva okanye ukolula amanqaku.

Inaliti yeMepolizumab ayisetyenziselwa ukunyanga uhlaselo lwequbuliso lweempawu zesifuba. Ugqirha wakho uya kumisela i-inhaler emfutshane ukuba ayisebenzise ngexesha lokuhlaselwa. Thetha nogqirha wakho malunga nendlela yokunyanga iimpawu zokuhlaselwa sisifuba ngokukhawuleza.Ukuba iimpawu zakho ze-asthma ziba nzima okanye ukuba uhlaselwa yi-asthma rhoqo, qiniseka ukuthetha nodokotela wakho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana inaliti ye-mepolizumab,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa inaliti ye-mepolizumab, nawaphi na amayeza, okanye nasiphi na isithako se-mepolizumab injection. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: i-corticosteroids yomlomo enje nge-prednisone (iRayos) okanye i-corticosteroid enganyangekiyo. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba awunayo inkuku (varicella) okanye ukhe wanalo naluphi na uhlobo losulelo olubangelwa ziintshulube.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa ufumana inaliti ye-mepolizumab, tsalela ugqirha wakho.
• ukuba unayo nayiphi na imeko yezonyango, enje ngesifo samathambo, okanye i-eczema (isifo sesikhumba), zinokuba mbi ngakumbi xa ithamo lakho lomlomo le-steroid linciphile. Tshela ugqirha wakho ukuba oku kuyenzeka okanye ukuba ufumana ezinye zeempawu ezilandelayo ngeli xesha: ukudinwa kakhulu, ubuthathaka bemisipha, okanye iintlungu; iintlungu ngesiquphe esiswini, emzimbeni osezantsi, okanye emilenzeni; ukuphelelwa ngumdla wokutya; ukuhla ukusinda; isisu esimoshakele; ukugabha; urhudo; isiyezi; isiqaqa; ukudakumba; ukucaphuka; kunye nokuba mnyama kolusu. Umzimba wakho usenokungakwazi ukujamelana noxinzelelo olufana notyando, ukugula, isifo sombefu okanye ukwenzakala ngeli xesha. Biza ugqirha wakho ngoko nangoko ukuba uyagula kwaye uqiniseke ukuba bonke ababonelela ngempilo abakunyangayo bayazi ukuba kutshanje wehlile umthamo wakho we-steroid yomlomo.
• xelela ugqirha wakho ukuba khange ugonyelwe irhashalala. Kusenokufuneka ufumane iyeza lokuthintela ukukhusela kwesi sifo.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Sebenzisa idosi ephosiweyo kwakamsinya nje emva kokuba uyikhumbule kwaye emva koko uqhubeke neshedyuli yakho yethamo yesiqhelo. Sukusebenzisa idosi ephindwe kabini ukwenza eyilahlekileyo. Biza ugqirha wakho ukuba uphose idosi kwaye unemibuzo malunga nokwenza.

Inaliti yeMepolizumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• iintlungu, ubomvu, ukudumba, ukufudumala, ukutshisa, okanye ukurhawuzelela kwindawo ekuthiwa yi-mepolizumab yafakwa
• intloko ebuhlungu
• ulusu olomileyo nolurhawuzayo kunye okanye ngaphandle kobomvu, irhashalala
• umqolo obuhlungu
• ukudumba kwezihlunu

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LOKUKHUSELEKILEYO OKUQHELEKILEYO, tsalela ugqirha wakho ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• ukuvutha okanye ukuphefumla nzima
• ukuqhawukelwa ngumphefumlo
• ukukhohlela
• ukuqina kwesifuba
• ukugungxula
• urhwebo
• irhashalala
• ukudumba kobuso, umlomo nolwimi
• kunzima ukugwinya
• isiqaqa okanye isiyezi

Inaliti yeMepolizumab inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Gcina inaliti ye-mepolizumab efrijini okanye kwikhatoni engavulwanga kubushushu begumbi ukuya kwiintsuku ezisi-7, kodwa ungayifrizi. Nje ukuba ususwe ebhokisini, inaliti ye-mepolizumab inokugcinwa kubushushu begumbi ukuya kwiiyure ezisi-8.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho angayalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwinaliti ye-mepolizumab.

Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nenaliti ye-mepolizumab.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Nucala^®