Inaliti yeDaratumumab

Umxholo

• Ngaphambi kokufumana inaliti ye-daratumumab,
• Inaliti yeDaratumumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo le-INDLELA, tsalela umnxeba kwangoko okanye ufumane unyango olukhawulezileyo.

Inaliti yeDaratumumab isetyenziswa yodwa okanye idityaniswe namanye amayeza ukunyanga i-myeloma emininzi (uhlobo lomhlaza womongo wethambo) kubantu abasandula ukufumanisa isifo nakubantu abangakhange baphucule ngonyango okanye abaye baphucula emva konyango namanye amayeza kodwa imeko ijikisiwe. UDaratumumab ukwiklasi yamayeza abizwa ngokuba yi-monoclonal antibodies. Isebenza ngokunceda umzimba ukuba ucothe okanye umise ukukhula kweeseli zomhlaza.

IDaratumumab iza njengamanzi (isisombululo) esinikwa ngaphakathi (emthanjeni) ngugqirha okanye ngumongikazi kwindawo yezempilo. Ugqirha wakho uya kuthatha isigqibo sokuba uyifumana kangaphi i-daratumumab ngokusekwe kwamanye amayeza anokuthi anikwe kunye nempendulo yomzimba wakho kolu nyango.

Ugqirha okanye umongikazi uyakukujonga ngokusondeleyo ngelixa ufumana ukumiliselwa kwaye emva koko uqiniseke ukuba awunampendulo imbi kunyango. Uya kunikwa amanye amayeza ukunceda ukuthintela nokunyanga iimpendulo kwi-daratumumab ngaphambi kokufakwa kwakho kunye nosuku lokuqala nolwesibini emva kokufumana iyeza lakho. Xelela ugqirha wakho okanye umongikazi kwangoko ukuba unazo naziphi na kwezi mpawu zilandelayo: ukukhohlela, ukuvutha, ukuqina komqala kunye nokucaphuka, ukurhawuzelela, ukubaleka, okanye impumlo exineneyo, intloko ebuhlungu, ukurhawuzelela, isicaphucaphu, ukugabha, umkhuhlane, ingqele, irhashalala, urhashalala, isiyezi, intloko emhlophe, ubunzima bokuphefumla, ukungonwabi esifubeni, okanye ukuphefumla kancinci.

Ugqirha wakho unokunciphisa idosi yakho ye-daratumumab okanye ayeke unyango lwakho okwethutyana okanye ngokusisigxina. Oku kuxhomekeke ekusebenzeni kakuhle kweyeza kunye neziphumo ebezingalindelekanga ohlangabezana nazo. Qiniseka ukuba uxelela ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho nge-daratumumab.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana inaliti ye-daratumumab,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-daratumumab, nawaphi na amanye amayeza, okanye naziphi na izithako kwi-injection ye-daratumumab. Buza usokhemesti wakho okanye ujonge ulwazi lomenzi wesigulana uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ufumana utofelo-gazi okanye ukuba unayo okanye wakha wanesibindi (irhashalala ebuhlungu eyenzeka emva kosulelo lwe-herpes zoster okanye inkuku), iingxaki zokuphefumla, i-hepatitis B (intsholongwane esosulela isibindi kwaye inokubangela isibindi esibi umonakalo), okanye isifo semiphunga esifana nesifo esinganyangekiyo semiphunga (COPD; iqela lezifo zemiphunga, ezibandakanya i-bronchitis engapheliyo kunye ne-emphysema).
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Kuya kufuneka usebenzise ulawulo lokuzalwa ukuthintela ukukhulelwa ngexesha lonyango lwakho kunye nedaratumumab kwaye ubuncinci iinyanga ezi-3 emva kwedosi yakho yokugqibela. Thetha nogqirha wakho malunga neentlobo zolawulo lokuzalwa oluza kukusebenzela. Ukuba ukhulelwa ngelixa ufumana inaliti ye-daratumumab, biza ugqirha wakho.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba ufumana inaliti ye-daratumumab.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Ukuba uphoswa idinga lokufumana i-daratumumab, biza ugqirha wakho kwangoko.

Inaliti yeDaratumumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukudinwa
• ukuqhina
• urhudo
• umqolo okanye iintlungu ezidibeneyo
• iintlungu ezingalweni, emilenzeni, okanye esifubeni
• ukunciphisa ukutya
• intloko ebuhlungu
• ukudumba kwezandla, amaqatha okanye iinyawo
• intlungu, ukutshisa, okanye ukubetha ezandleni nasezinyaweni
• ukudumba kwezihlunu
• ubunzima bokulala okanye ukulala

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo le-INDLELA, tsalela umnxeba kwangoko okanye ufumane unyango olukhawulezileyo.

• ukugruzuka okanye ukopha
• ifiva
• ukudinwa kakhulu
• mthubi ulusu okanye amehlo

Inaliti yeDaratumumab inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya ku-odola iimvavanyo ezithile zebhu ngaphambi nangexesha lonyango lwakho ukujonga impendulo yomzimba wakho kwisitofu sedaratumumab.

Ngaphambi kokuba uvavanywe elebhu, xelela ugqirha wakho kunye nabasebenzi ukuba ufumana okanye ufumene inaliti ye-daratumumab. IDaratumumab inokuchaphazela iziphumo zovavanyo oluthile lwelabhoratri.

IDaratumumab inokuchaphazela iziphumo zovavanyo lwegazi ukuya kuthi ga kwiinyanga ezi-6 emva kwedosi yakho yokugqibela. Ngaphambi kokuba utofelwe igazi, xelela ugqirha wakho kunye nabasebenzi baselebhu ukuba ufumana okanye ufumana inaliti ye-daratumumab. Ugqirha wakho uya kwenza uvavanyo lwegazi ukuthelekisa uhlobo lwegazi lakho ngaphambi kokuba uqale unyango kunye nedaratumumab.

Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nenaliti ye-daratumumab.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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