Elbasvir kunye neGrazoprevir
Umxholo
- Ngaphambi kokuba uthathe i-elbasvir kunye negrazoprevir,
- I-Elbasvir kunye negrazoprevir inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
- Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zikwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:
Usenokuba bosulelwe yi-hepatitis B (intsholongwane esosulela isibindi kwaye inokubangela ukonakala kwesibindi) kodwa ungabinazo iimpawu zesifo. Kule meko, ukuthatha indibaniselwano ye-elbasvir kunye ne-grazoprevir kunokunyusa umngcipheko wokuba usulelo lwakho lube lukhulu kakhulu okanye lusongele ubomi kwaye uya kuba neempawu. Tshela ugqirha wakho ukuba ukhe wosulelwa yintsholongwane ye-hepatitis B. Ugqirha wakho uya ku-odola uvavanyo lwegazi ukuze abone ukuba unesifo bosulelo lwe-hepatitis B. Ugqirha wakho uya kukujonga esweni usulelo lwe-hepatitis B ngexesha kunye neenyanga ezimbalwa emva konyango lwakho. Ukuba kukho imfuneko, ugqirha unokukunika amayeza ukunyanga olu sulelo ngaphambi nangexesha lonyango lwakho ngokudibanisa i-elbasvir kunye ne-grazoprevir. Ukuba unazo naziphi na kwezi mpawu zilandelayo ngexesha okanye emva konyango lwakho, tsalela umnxeba kwangoko: ukudinwa kakhulu; ubumthubi besikhumba okanye amehlo; ukuphelelwa ngumdla wokutya; isicaphucaphu okanye ukugabha; ilindle eluthuthu; iintlungu kwicala lasekunene kwicala lesisu; okanye umchamo omnyama.
Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho angayalela iimvavanyo ezithile ngaphambi, ngexesha, nasemva konyango lwakho ukujonga impendulo yomzimba wakho kwindibaniselwano ye-elbasvir kunye ne-grazoprevir.
Thetha nogqirha wakho malunga nomngcipheko (s) wokuthatha indibaniselwano ye-elbasvir kunye negrazoprevir.
Indibaniselwano ye-elbasvir kunye ne-grazoprevir isetyenziswa yodwa okanye idityaniswe ne-ribavirin (Copegus, Rebetol, Ribasphere, Virazole) ukunyanga uhlobo oluthile losulelo olungapheliyo (lwexesha elide) lwe-hepatitis C (ukudumba kwesibindi okubangelwa yintsholongwane). U-Elbasvir ukwiklasi yamayeza antiviral abizwa ngokuba yi-HCV NS5A inhibitors. Isebenza ngokumisa intsholongwane ebangela i-hepatitis C ukuba isasazeke emzimbeni. I-Grazoprevir ikudidi lwamayeza abizwa ngokuba zii-protease inhibitors. Isebenza ngokunciphisa inani le-virus ye-hepatitis C (HCV) emzimbeni. Ayaziwa ukuba i-elbasvir kunye ne-grazoprevir zithintela ukusasazeka kwe-hepatitis C kwabanye abantu.
Indibaniselwano ye-elbasvir kunye negrazoprevir iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kunye okanye ngaphandle kokutya kube kanye yonke imihla iiveki ezili-12 ukuya kwezi-16. Thatha i-elbasvir kunye ne-grazoprevir ngexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-elbasvir kunye ne-grazoprevir ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.
Qhubeka nokuthatha i-elbasvir kunye negrazoprevir nokuba uziva uphilile. Ubude bonyango lwakho buxhomekeke kwimeko yakho, ukuba uphendula njani kunyango, kwaye nokuba uneziphumo ebezingalindelekanga ezibi. Sukuyeka ukuthatha i-elbasvir kunye negrazoprevir ngaphandle kokuthetha nogqirha wakho.
Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.
Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.
Ngaphambi kokuba uthathe i-elbasvir kunye negrazoprevir,
- xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-elbasvir, i-grazoprevir, nawaphi na amanye amayeza, okanye nasiphi na isithako esikwipilisi ye-elbasvir kunye ne-grazoprevir. Buza usokhemesti wakho uluhlu lwezithako.
- xelela ugqirha wakho ukuba uthatha i-atazanavir (Reyataz), carbamazepine (Carbatrol, Epitol, Equetro, Tegretol), cyclosporine (Gengraf, Neoral, Sandimmune), darunavir (Prezista, e Prezcobix), efavirenz (Sustiva, e Atripla), lopina eKaletra), phenytoin (Dilantin, Phenytek), rifampin (Rifadin, Rimactane, eRifamate, eRifater), saquinavir (Invirase), eSt John's wort, okanye kwi-tipranavir (Aptivus). Ugqirha wakho uya kukuxelela ukuba ungathathi i-elbasvir kunye ne-grazoprevir ukuba uthatha elinye okanye ngaphezulu kwala mayeza.
- xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: bosentan (Tracleer); i-cobicistat ithathwe kunye ne-elvitegravir, emtricitabine, kunye ne-tenofovir (Genvoya, Stribild); i-etravirine (ukungakhathali); amayeza okunyanga i-cholesterol ephezulu njenge-atorvastatin (Lipitor, eCaduet), fluvastatin (Lescol XL), lovastatin (Altoprev), rosuvastatin (Crestor), kunye ne-simvastatin (iZocor, eVytorin); ketoconazole; imodafinil (Provigil); nafcillin; itacrolimus (Astagraf, Envarsus, Prograf, nabanye); kunye ne-warfarin (Coumadin, Jantoven). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-elbasvir kunye ne-grazoprevir, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
- xelela ugqirha wakho ukuba ukhe wanalo naluphi na uhlobo lwesifo sesibindi ngaphandle kwehepatitis C. Ugqirha wakho angakuxelela ukuba ungathathi i-elbasvir kunye ne-grazoprevir.
- xelela ugqirha wakho ukuba ubunalo okanye ulindele ukufakelwa isibindi okanye ukuba unayo intsholongwane kaGawulayo.
- xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-elbasvir kunye negrazoprevir, biza ugqirha wakho.
Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.
Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.
I-Elbasvir kunye negrazoprevir inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
- urhudo
- intloko ebuhlungu
- ubunzima bokulala okanye ukulala
Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zikwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:
- ukozela
- ukudideka
- ukudumba kwendawo yesisu
- ukugabha igazi okanye into ebonakala ngathi yindawo yekhofi
- mnyama, mnyama, okanye ilindle eligazi
I-Elbasvir kunye ne-grazoprevir inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.
Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).
Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Musa ukususa iipilisi kwiphakheji kude kube ngaphambi kokusetyenziswa.
Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org
Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese.Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.
Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.
Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.
Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.
- Zepatier®