Rucaparib

Umxholo

• Ngaphambi kokuba uthathe i-rucaparib,
• I-Rucaparib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

I-Rucaparib isetyenziselwa ukunceda ukugcina impendulo kolunye unyango kwezinye iintlobo zomhlaza wesibeleko (umhlaza oqala kumalungu okuzala amabhinqa apho kwenziwa khona amaqanda), ityhubhu (ityhubhu ehambisa amaqanda akhululwe ngamaqanda esibelekweni), kunye neprayimari I-peritoneal (ungqimba lwethishu eligcina isisu) umhlaza obuyileyo kubantu abadala abaphendule ngokupheleleyo okanye ngokungaphenduliyo kwezinye iindlela zonyango lwe-chemotherapy. Isetyenziselwa ukunyanga iintlobo ezithile zomhlaza we-ovari, umhlaza wesifo se-fallopian tube, kunye nomhlaza wokuqala we-peritoneal kubantu abanesifo esithile esifumene unyango kunye nezinye iindlela zonyango ezimbini zonyango. I-Rucaparib ikwasetyenziselwa ukunyanga iintlobo ezithile zomhlaza wesibeletho ethe yasasazeka yaya kwezinye iindawo emzimbeni kubantu abanesifo esithile esifumene olunye unyango. URucaparib ukwiklasi yamayeza abizwa ngokuba yi-poly (ADP-ribose) polymerase (PARP) inhibitors. Isebenza ngokubulala iiseli zomhlaza.

URucaparib uza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kunye okanye ngaphandle kokutya kabini imihla ngemihla, malunga neeyure ezili-12 ukwahlukana. Thatha i-rucaparib ngeenxa zonke ngamaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-rucaparib ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ugqirha wakho unokufuna ukulibazisa unyango lwakho okanye uhlengahlengise idosi yakho ye-rucaparib ngokuxhomekeke kwimpendulo yakho kunyango kunye naziphi na iziphumo ebezingalindelekanga ohlangabezana nazo. Thetha nogqirha wakho malunga nendlela oziva ngayo ngexesha lonyango lwakho. Sukuyeka ukuthatha i-rucaparib ngaphandle kokuthetha nogqirha wakho.

Ukuba uyagabha emva kokuthatha i-rucaparib, musa ukuthatha elinye idosi. Qhubeka neshedyuli yakho yesiqhelo.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-rucaparib,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-rucaparib, nawaphi na amanye amayeza, okanye naziphi na izithako kwiipilisi ze-rucaparib. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, othabathayo okanye oceba ukuthatha Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: warfarin (Coumadin, Jantoven). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana ne-rucaparib, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye ucwangcise ukuba ngutata womntwana. Akufanele ukhulelwe ngelixa uthatha i-rucaparib. Uya kudinga ukuthatha uvavanyo lokukhulelwa ngaphambi kokuba uqale unyango. Sebenzisa ulawulo lokuzalwa olusebenzayo ngexesha lonyango lwakho nge-rucaparib kunye neenyanga ezi-6 emva kwedosi yokugqibela. Ukuba uyindoda, wena neqabane lakho labasetyhini kufuneka nisebenzise ulawulo lokuzalwa ngexesha lonyango kunye nakwiinyanga ezi-3 emva kwedosi yokugqibela. Thetha nogqirha wakho malunga neendlela zokulawula ukuzalwa eziza kukusebenzela. Ukuba ukhulelwa ngelixa uthatha i-rucaparib, biza ugqirha wakho.
• xelela ugqirha wakho ukuba ucwangcisa ukuncancisa. Akufanele uncancise ngexesha lonyango lwakho nge-rucaparib kunye nakwiiveki ezi-2 emva kwedosi yakho yokugqibela.
• cwangcisa ukuthintela ukukhanya elangeni ngokungeyomfuneko okanye ixesha elide kwaye unxibe iimpahla zokuzikhusela, umnqwazi, iiglasi zelanga kunye nescreen selanga. I-Rucaparib inokwenza ulusu lwakho lubuthathaka kwilanga.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yokulinganisa Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Rucaparib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• ukuqhina
• urhudo
• isisu esibuhlungu
• Ukuphelelwa ngumdla wokutya
• incasa embi emlonyeni
• ukurhawuzelela
• izilonda zomlomo
• Ukuxinana kwempumlo, impumlo egudileyo, ukuthimla, umqala obuhlungu okanye ukukrwempa, okanye ukukhohlela

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

• ubuthathaka, ukudinwa, umkhuhlane, ukunciphisa umzimba, ukugruzuka ngokulula okanye ukopha, okanye igazi kumchamo okanye esitulweni
• ulusu oluthuthu
• ukuqhawukelwa ngumphefumlo
• irhashalala

I-Rucaparib inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyala iimvavanyo ezithile zebhu ngaphambi kokuba uqale kwaye ngamaxesha ahlukeneyo kunyango lwakho ukujonga impendulo yomzimba wakho kwi-rucaparib. Kwezinye iimeko, ugqirha wakho uya kuyalela uvavanyo lwelebhu ngaphambi kokuba uqale unyango lwakho ukuze ubone ukuba umhlaza wakho unganyangwa ngerucaparib.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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