Inaliti yeSarilumab

Umxholo

• Ngaphambi kokuba uthathe inaliti yesarilumab,
• Inaliti yeSarilumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

Inaliti ye-Sarilumab inokunciphisa amandla akho okulwa usulelo kwaye yonyuse umngcipheko wokuba ufumane usulelo olubi, kubandakanya ukungunda okunamandla, ibhaktiriya, okanye usulelo lwentsholongwane olusasazeka emzimbeni wonke. Ezi zifo zingafuna ukunyangwa esibhedlele kwaye zingabangela ukufa. Tshela ugqirha wakho ukuba uhlala ufumana naluphi na uhlobo losulelo okanye ukuba ucinga ukuba unalo naluphi na uhlobo losulelo ngoku. Oku kubandakanya usulelo oluncinci (njengokusikwa okuvulekileyo okanye izilonda), usulelo olufikayo (olufana nezilonda ezibandayo), kunye nosulelo olungapheliyo olungapheliyo. Xelela ugqirha wakho ukuba ukhe unesifo seswekile, intsholongwane kaGawulayo (i-HIV), ufumene isifo se-immunodeficiency syndrome (i-AIDS), okanye nayiphi na imeko echaphazela amajoni akho omzimba. Kuya kufuneka uxelele ugqirha wakho ukuba uhlala, ukhe waphila, ukuba ukhe waya kwiindawo ezifana ne-Ohio okanye i-Mississippi river valleys apho kukho izifo zokungunda ezixhaphakileyo. Buza ugqirha wakho ukuba awuqinisekanga ukuba ezi zifo zixhaphakile kwindawo yakho. Xelela ugqirha wakho ukuba uthatha amayeza anciphisa umsebenzi wamajoni omzimba afana nala alandelayo: abatacept (Orencia); adalimumab (Humira); anakinra (iKineret); isetifolizumab pegol (Cimzia); etanercept (Enbrel); igolimumab (iSimponi); infliximab (Remicade); imethotrexate (Otrexup, Rasuvo, Trexall); rituximab (Rituxan); i-steroids kubandakanya i-dexamethasone, i-methylprednisolone (A-Methapred, Medrol, Solu-Medrol), prednisolone (Orapred, Pediapred), kunye ne-prednisone (iRayos); tocilizumab (Actemra) kunye ne-tofacitinib (Xeljanz).

Ugqirha wakho uya kukubeka esweni ngeempawu zosulelo ngexesha nasemva konyango lwakho. Ukuba unazo naziphi na kwezi mpawu zilandelayo ngaphambi kokuba uqale unyango lwakho okanye ukuba unazo naziphi na kwezi mpawu zilandelayo okanye emva nje konyango lwakho, tsalela umnxeba kwangoko: fiva; ukubila; Ukugodola; iintlungu zemisipha; ukukhohlela; ukukhohlela umchamo wegazi; ukuqhawukelwa ngumphefumlo; ukuhla ukusinda; ulusu olufudumeleyo, olubomvu, okanye olubuhlungu; izilonda eluswini; rhoqo, ebuhlungu, okanye evuthayo xa uchama; urhudo; isisu esibuhlungu; okanye ukudinwa okugqithisileyo.

Usenokuba sele wosulelwe sisifo sephepha (i-TB; isifo esibuhlungu semiphunga) kodwa ungabi nazimpawu zesi sifo. Kule meko, ukusebenzisa inaliti ye-sarilumab kunokwenza usulelo lwakho lube lubi kakhulu kwaye kubangele ukuba ube neempawu. Ugqirha wakho uza kuvavanya ulusu ukuze abone ukuba unesifo se-TB esingasebenziyo phambi kokuba uqale unyango lwakho ngenaliti yesarilumab. Ukuba kukho imfuneko, ugqirha wakho uya kukunika amayeza ukunyanga esi sifo ngaphambi kokuba uqale usebenzise inaliti yesarilumab. Xelela ugqirha wakho ukuba ukhe wakha okanye wakha wanayo na i-TB, ukuba ngaba wakhe wahlala okanye watyelela ilizwe apho ixhaphake kakhulu i-TB, okanye ukuba wakhe wakunye nomntu one-TB. Ukuba unazo naziphi na kwezi mpawu zilandelayo ze-TB, okanye ukuba uvela kwezi mpawu ngexesha lonyango lwakho, tsalela umnxeba kwangoko: ukukhohlela, ukukhohlela umchamo wegazi, ukwehla kobunzima, ukulahleka kwethoni yezihlunu, okanye umkhuhlane.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango ngenaliti yesarilumab kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Inaliti yeSarilumab isetyenziswa yodwa okanye namanye amayeza ukunyanga isifo samathambo (RA: imeko apho umzimba uhlasela amalungu ayo ubangela iintlungu, ukudumba, kunye nokuphulukana nomsebenzi). I-Sarilumab ihlala isetyenziswa ngabantu abangakhange bancedwe ngamanye amayeza e-RA okanye abangakwazanga ukuthatha la mayeza. Inaliti yeSarilumab ikudidi lwamayeza abizwa ngokuba yi-interleukin-6 (IL-6) receptor inhibitors. Isebenza ngokuthintela ukusebenza kwe-interleukin-6, into esemzimbeni ebangela ukudumba.

Inaliti yeSarilumab iza njengesirinji ekhethiweyo ukujova (ngaphantsi kolusu). Ihlala isetyenziswa kanye kwiiveki ezi-2.Ugqirha wakho unokuthatha isigqibo sokuba wena okanye umntu omkhathalelayo unokwenza inaliti ekhaya. Ugqirha wakho uyakukubonisa okanye umntu oza kuthi afake iyeza ukuba ungalitofa njani. Wena okanye umntu oza kutofa iyeza kufuneka ufunde imiyalelo ebhaliweyo yokusetyenziswa okuza nonyango. Qiniseka ukuba ubuza ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo malunga nokuba ungalifaka njani iyeza.

Susa iyeza kwifriji kwimizuzu engama-30 ngaphambi kokuba ulungele ukutofa amayeza. Yibeke endaweni ethe tyaba kwaye uyivumele ukuba ifikelele kubushushu begumbi. Xa ususa isirinji ekhethiweyo ebhokisini, lumka ukuyibamba kuphela embindini wesirinji kwaye sukuyigungqisa isirinji okanye ususe isiciko esigqume inaliti. Sukuzama ukufudumeza amayeza ngokuwatshisa kwimicrowave, ngokuwabeka emanzini afudumeleyo okanye elangeni ngqo, okanye ngayo nayiphi na enye indlela.

Ngaphambi kokufaka inaliti, jonga isirinji ekhethiweyo ukuqinisekisa ukuba umhla wokuphelelwa uprintwe kwiphakheji awudlulanga. Jonga ngokusondeleyo ulwelo kwisirinji. Ulwelo kufuneka lucace okanye lube mthubi mthubi kwaye akufuneki lubenamafu okanye lube nebala okanye lube namaqhuma okanye amasuntswana. Jonga ukuba isirinji ibonakala yonakele na okanye inaliti ayikho okanye ayiqhotyoshelwanga. Fowunela usokhemesti wakho ukuba kukho naziphi na iingxaki kwaye ungalitofisi iyeza.

Unokufaka inaliti yesarilumab ngaphambili kwamathanga okanye naphina esiswini sakho ngaphandle kwenkaba yakho (iqhosha lesisu) kunye nendawo eyi-intshi ezi-2 ejikeleze yona. Ukuba omnye umntu utofa iyeza lakho, indawo engaphandle yeengalo ezingaphezulu inokusetyenziswa. Musa ukujova iyeza kulusu oluthambileyo, olonzakeleyo, olonakeleyo okanye olunezikrobo. Khetha indawo eyahlukileyo ngalo lonke ixesha utofa iyeza.

Sukuyisebenzisa kwakhona iisirinji ezizalisiweyo ze-sarilumab kwaye ungaziphindi iisirinji emva kokusetyenziswa. Lahla iisirinji ezisetyenzisiweyo kwisitya esinganyangekiyo kwaye ubuze usokhemesti ukuba usilahla njani isikhongozeli.

Ugqirha wakho uyakukujonga ngononophelo ukuze ubone ukuba isebenza njani inaliti ye-sarilumab. Ugqirha wakho unokuhlengahlengisa idosi yakho okanye ulibazise okanye uyeke unyango lwakho ngokuxhomekeke kwimpendulo yakho kolu nyango. Kubalulekile ukuxelela ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho.

Inaliti yeSarilumab inokunceda ukulawula iimpawu zakho, kodwa ayizukuyinyanga imeko yakho. Qhubeka usebenzise inaliti yesarilumab nokuba uziva uphilile. Sukuyeka ukusebenzisa inaliti yesarilumab ngaphandle kokuthetha nogqirha wakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe inaliti yesarilumab,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-sarilumab, nawaphi na amanye amayeza, okanye naziphi na izithako kwi-sarilumab injection. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ngokukhankanya amayeza adweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO kunye nayo nayiphi na kwezi zinto zilandelayo: iasprini kunye nezinye iziyobisi ezichasayo (i-NSAIDs) ezinje nge-ibuprofen (Advil, Motrin), kunye ne-naproxen (Aleve, Anaprox, abanye); atorvastatin (Lipitor, kwiCaduet); i-clarithromycin (i-Biaxin, kwi-Prevpac); icyclosporine (Gengraf, Neoral, Sandimmune); i-erythromycin (i-EES, i-Eryc, i-PCE); I-lovastatin (Altoprev); izinto zokucwangcisa ngomlomo (iipilisi zolawulo lokuzalwa); quinidine (kwiNuedexta); isimvastatin (iZocor, eVytorin); i-sirolimus (iRamamune, iTorisel); itacrolimus (Astagraf, Envarsus XR, Prograf); telithromycin (Ketek); Inophylline (Theo-24, Theochron); kunye ne-warfarin (Coumadin, Jantoven). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana nenaliti ye-sarilumab, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba ukhe wakha waba ne-diverticulitis (iipokotho ezincinci kumngxunya wamathumbu amakhulu anokudumba), izilonda esiswini sakho okanye emathunjini, umhlaza, okanye i-hepatitis B okanye esinye isifo sesibindi. Xelela ugqirha wakho ukuba uceba ukwenza utyando okanye inkqubo yonyango kungekudala.
• xelela ugqirha wakho ukuba usandula ukufumana okanye ucwangciselwe ukufumana naziphi na izitofu. Akufanele ufumane naluphi na ugonyo ngelixa usebenzisa inaliti ye-sarilumab ngaphandle kokuthetha nogqirha wakho.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwe ngelixa uthatha inaliti ye-sarilumab, tsalela ugqirha wakho. Ukuba ufumene inaliti yesarilumab ngelixa ukhulelwe, xelela ugqirha ngaphambi kokuba umntwana afumane ugonyo.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha inaliti yesarilumab.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Buza ugqirha wakho ukuba wenzeni ukuba uyalibala ukujova idosi. Sukusebenzisa idosi ephindwe kabini ukwenza eyilahlekileyo.

Inaliti yeSarilumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• impumlo egobileyo okanye egobayo
• ukuba bomvu okanye ukurhawuzelela kufutshane nendawo leyo iyeza lafakwa kuyo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

• ukopha okanye ukugruzuka ngokulula
• irhashalala
• urhwebo
• ubunzima bokuginya okanye ukuphefumla
• ukudumba kwemilebe yakho, ulwimi, okanye ubuso
• iintlungu zesifuba
• uziva unesiyezi okanye ufe isiqaqa
• isisu esibuhlungu
• ukugabha
• buhlungu, ukutshisa, ukuba ndindisholo, okanye ukurhawuzelela ulusu okanye amadyunguza kulusu lwakho

Amayeza afanayo ngenaliti ye-sarilumab inokubangela umngcipheko okhulayo wokuba nomhlaza. Thetha nogqirha wakho malunga neengozi zokusebenzisa eli yeza.

Inaliti yeSarilumab inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa usebenzisa eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina la mayeza kwikhathoni engenile ukuyikhusela ekukhanyeni, ivalwe ngokuqinileyo, kwaye ingafumaneki ebantwaneni. Yigcine efrijini kodwa ungagodoli. Ukuba iyeza ligcinwe ngaphandle kwefriji, kufuneka lisetyenziswe ngaphakathi kweentsuku ezili-14.

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zelebhu ukujonga impendulo yomzimba wakho kwisitofu sarilumab.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Kevzara^®