Inaliti yeGuselkumab

Umxholo

• Ngaphambi kokusebenzisa inaliti ye-guselkumab,
• Inaliti yeGuselkumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, yeka ukusebenzisa inaliti ye-guselkumab kwaye ubize ugqirha ngoko nangoko okanye ufumane unyango olungxamisekileyo:

Inaliti ye-Guselkumab isetyenziselwa ukunyanga i-plaque psoriasis (isifo solusu apho umbala obomvu, onamaxolo wenza iindawo ezithile zomzimba) kubantu abadala abane-psoriasis yabo ebukhali kakhulu ukuba inganyangwa ngamayeza ezinto kuphela. Isetyenziselwa sodwa okanye ngokudibeneyo namanye amayeza ukunyanga i-psoriatic arthritis (imeko ebangela iintlungu ezidibeneyo kunye nokudumba kunye nezikali kulusu) kubantu abadala. Inaliti ye-Guselkumab ikwiklasi yamayeza abizwa ngokuba ngamachiza omzimba. Isebenza ngokumisa isenzo seeseli ezithile emzimbeni ezibangela iimpawu ze-psoriasis.

Inaliti ye-Guselkumab iza njengesisombululo (ulwelo) kwisirinji ekhethiweyo kunye nesixhobo sokufaka inaliti esizenzekelayo ukufaka inaliti (phantsi kolusu). Ihlala itofwe kanye kwiiveki ezi-4 kwiidosi ezimbini zokuqala ize iqhubeke kube kanye kwiiveki ezisi-8. Sebenzisa inaliti ye-guselkumab kanye njengoko kuyalelwe. Musa ukuyitofa ngaphezulu okanye ngaphantsi okanye uyitofe rhoqo kunokuba umiselwe ngugqirha.

Uya kufumana idosi yakho yokuqala yenaliti ye-guselkumab kwiofisi kagqirha wakho. Emva koko, ugqirha wakho unokukuvumela ukuba utofe i-guselkumab ngokwakho okanye ukhathalelwe unike inaliti. Buza ugqirha wakho okanye usokhemesti akubonise okanye umntu oza kunika inaliti indlela yokujova i-guselkumab. Ngaphambi kokuba usebenzise inaliti ye-guselkumab ngokwakho okokuqala, funda imiyalelo ebhaliweyo eza nayo.

Sebenzisa isirinji nganye okanye isixhobo esizenzekelayo sokufaka inaliti kube kanye kwaye utofe isisombululo kwisirinji. Lahla isirinji esetyenzisiweyo okanye isixhobo nokuba kusekho amayeza aseleyo kuwo. Lahla iisirinji okanye izixhobo ezisetyenzisiweyo kwisitya esinganyangekiyo. Thetha nogqirha wakho okanye usokhemesti malunga nokusilahla isikhongozeli esinganyangekiyo.

Susa isirinji ekhethiweyo okanye isixhobo esizenzekelayo kwifriji, beka isirinji kwindawo ethe tyaba ngaphandle kokususa isiciko senaliti okanye ikepusi yesixhobo, kwaye usivumele sifudumale kubushushu begumbi kangangemizuzu engama-30 ngaphambi kokuba ulungele ukutofa iyeza. Sukuzama ukufudumeza amayeza ngokuwatshisa kwimicrowave, ngokuwabeka emanzini ashushu, uwashiye elangeni, okanye ngayo nayiphi na enye indlela.

Musa ukushukumisa isirinji ekhethiweyo okanye isixhobo sokuzenzekelayo esine-guselkumab. Sukusebenzisa i-guselkumab isirinji ekhethiweyo ukuba ilahliwe; inamalungu eglasi kwaye kufuneka iphathwe ngononophelo.

Soloko ujonga isisombululo se-guselkumab ngaphambi kokuyifaka. Jonga ukuba umhla wokuphelelwa awukadluli, kwaye ulwelo lucacile kwaye alunambala kwisisombululo esimthubi. Umbane unokuqulatha amasuntswana abonakalayo. Sukusebenzisa isirinji ekhethiweyo okanye isixhobo ukuba sonakele, siphelelwe lixesha, sinqabile, okanye ukuba ulwelo lunamafu, lubala, okanye luqulathe amasuntswana amakhulu.

Faka inaliti ye-guselkumab ngaphakathi kwemizuzu emi-5 yokususa isiciko senaliti okanye ikepusi yesixhobo. Sukufaka isiciko senaliti okanye ikepusi yezixhobo kuba oko kunokonakalisa inaliti okanye kubangele ukwenzakala. Sukusebenzisa isixhobo sokuzenzekelayo esilahliweyo emva kokususwa kwekepusi yesixhobo.

Unokufaka inaliti ye-guselkumab naphina ngaphambili kwethanga lakho (umlenze ongasentla), umva weengalo ezingaphezulu, okanye isisu (isisu) ngaphandle kwenkaba yakho kunye nendawo eyi-intshi ezi-5 (iisentimitha ezi-5) ngeenxa zonke. Ukunciphisa amathuba okuqaqamba okanye ububomvu, sebenzisa indawo eyahlukileyo yenaliti nganye. Musa ukujova kwindawo apho ulusu luthambile, lutyumkileyo, lubomvu, lukhuni.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango ngenaliti ye-guselkumab. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) ukufumana isiKhokelo seMithi, okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi kunye neMiyalelo Ukusetyenziswa.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa inaliti ye-guselkumab,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana nenaliti ye-guselkumab, nawaphi na amanye amayeza, okanye naziphi na izithako kwi-guselkumab injection. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa usebenzisa inaliti ye-guselkumab, tsalela ugqirha wakho.
• jongana nogqirha wakho ukubona ukuba ufuna ukufumana naluphi na ugonyo. Kubalulekile ukuba ube nazo zonke izitofu ezifanelekileyo kwiminyaka yakho ngaphambi kokuba uqale unyango lwakho ngenaliti ye-guselkumab. Awunalo ugonyo ngexesha lonyango ngaphandle kokuthetha nogqirha wakho. Thetha nogqirha wakho ukuba kukho umntu osendlwini yakho ofuna ukufumana isitofu ngexesha lonyango lwakho ngenaliti ye-guselkumab.
• Kuya kufuneka uyazi ukuba inaliti ye-guselkumab inokunciphisa amandla akho okulwa usulelo kwiibhaktiriya, intsholongwane kunye nefungi kwaye wandise umngcipheko wokuba uza kufumana usulelo olubi okanye olusongela ubomi. Tshela ugqirha wakho ukuba uhlala ufumana naluphi na uhlobo losulelo okanye ukuba unayo okanye ucinga ukuba unalo naluphi na uhlobo losulelo ngoku. Oku kubandakanya izilonda ezitsha okanye ezitshintshayo zolusu, ukosuleleka okuncinci (njengokucheba okuvulekileyo okanye izilonda), usulelo olufikayo (olufana nezilonda ezibandayo), kunye nosulelo olungapheliyo olungapheliyo. Ukuba ufumana naziphi na kwezi mpawu zilandelayo ngexesha okanye kungekudala emva konyango lwakho ngenaliti ye-guselkumab, biza ugqirha ngoko nangoko: ukubila; Ukugodola; iintlungu zemisipha; ukukhohlela; ukuqhawukelwa ngumphefumlo; ifiva; ukuhla ukusinda; ukudinwa kakhulu; iimpawu ezifana nomkhuhlane; ukugabha; umqala obuhkungu; i-runny, impumlo efakiweyo, okanye ukuthimla; ulusu olufudumeleyo, olubomvu, okanye olubuhlungu; ukuchama kabuhlungu okanye rhoqo; urhudo; isisu esibuhlungu; okanye ezinye iimpawu zosulelo.
• Kuya kufuneka uyazi ukuba ukusebenzisa inaliti ye-guselkumab yonyusa umngcipheko wokuba ube nesifo sephepha (i-TB; usulelo olubi lwemiphunga), ngakumbi ukuba sele usulelekile sisifo sephepha kodwa ungenazimpawu zesifo. Xelela ugqirha wakho ukuba ukhe wakha okanye wakha wanayo na i-TB, ukuba ngaba wakhe wahlala kwilizwe apho ixhaphake kakhulu i-TB, okanye ukuba ukhe wakufutshane nomntu one-TB. Ugqirha wakho uza kwenza uvavanyo lolusu ukuze abone ukuba unesifo se-TB esingasebenziyo. Ukuba kunyanzelekile, ugqirha wakho uya kukunika amayeza ukunyanga olu suleleko ngaphambi kokuba uqale ukusebenzisa inaliti ye-guselkumab. Ukuba unazo naziphi na kwezi mpawu zilandelayo ze-TB, okanye ukuba uvela kwezi mpawu ngexesha lonyango lwakho, tsalela umnxeba kwangoko: ukukhohlela, iintlungu esifubeni, ukukhohlela igazi okanye amafinyila, ubuthathaka okanye ukudinwa, ukwehla emzimbeni, ukungabi namdla wokutya, Ukugodola, umkhuhlane, okanye ukubila ebusuku.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Sebenzisa idosi ephosiweyo kwakamsinya nje emva kokuba uyikhumbule kwaye emva koko uqhubeke neshedyuli yakho yethamo yesiqhelo. Sukusebenzisa idosi ephindwe kabini ukwenza eyilahlekileyo. Biza ugqirha wakho ukuba awucacanga malunga neshedyuli yakho yedosi.

Inaliti yeGuselkumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• intloko ebuhlungu
• ububomvu, ukurhawuzelela, ukudumba, iintlungu, ukujika kombala, okanye ukucaphuka kwindawo yenaliti
• intlungu edibeneyo
• urhudo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, yeka ukusebenzisa inaliti ye-guselkumab kwaye ubize ugqirha ngoko nangoko okanye ufumane unyango olungxamisekileyo:

• irhashalala
• urhwebo
• ukurhawuzelela
• ndiziva ndidiniwe okanye ndinentloko elula
• ukudumba kobuso, amehlo, imilebe, umlomo, umqala, okanye ulwimi
• ubunzima bokuphefumla
• ukuqina kwesifuba okanye komqala

Inaliti yeGuselkumab inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa usebenzisa eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina inaliti ye-guselkumab kwifriji, kodwa ungagodoli. Gcina iisirinji ezikhethiweyo okanye izixhobo zeenaliti ezizenzekelayo kwiibhokisi zazo zokuqala ukuzikhusela ekukhanyeni.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho.

Musa ukuvumela omnye umntu asebenzise amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Tremfya^®