Umbhali: Marcus Baldwin
Umhla Wokudalwa: 17 Isilimela 2021
Hlaziya Umhla: 16 Eyenkanga 2024
Anonim
Use of Stiripentol in Dravet Syndrome with Dr. Ben Menachem,
Ividiyo: Use of Stiripentol in Dravet Syndrome with Dr. Ben Menachem,

Umxholo

I-Stiripentol isetyenziswa kunye ne-clobazam (Onfi®) ukulawula ukuxhuzula kubantu abadala nakubantwana abaneminyaka emi-2 ubudala nangaphezulu abane-Dravet syndrome (isifo esiqala ebuntwaneni kwaye sibangela ukuxhuzula kwaye kamva kungakhokelela kulibaziseko lophuhliso kunye notshintsho ekutyeni, ekulinganiseni nasekuhambeni). I-Stiripentol ikudidi lwamayeza abizwa ngokuba zii-anticonvulsants. Isebenza ngokunciphisa ukonwaba okungaqhelekanga kwingqondo.

I-Stiripentol iza njengecapsule kunye ne-powder yomlomo yokumiswa ukuze kuthathwe ngomlomo. Ihlala ithathwa kabini okanye kathathu ngemini ngexesha lesidlo. Thatha i-stiripentol malunga nexesha elifanayo (ii) yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-stiripentol ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Gwinya zonke njengezingxobo ngeglasi yamanzi; musa ukuwaphula okanye uwavule.

Ukuba uthatha umgubo, kufuneka uwuxube namanzi kwangoko ngaphambi kokuba uwuthathe. Ugqirha uza kukuxelela ukuba zingaphi iipakethi ze-stiripentol powder oyisebenzisayo kunye nokuba ungakanani amanzi onokuxuba. Yifunde ngononophelo imiyalelo yomenzi echaza indlela yokuxuba kunye nokuthatha idosi ye-stiripentol. Qiniseka ukuba ubuza usokhemesti okanye ugqirha ukuba unayo nayiphi na imibuzo malunga nendlela yokuxuba okanye ukuthatha la mayeza.


I-Stiripentol ilawula imeko yakho kodwa ayiyinyanga. Qhubeka uthathe i-stiripentol nokuba uziva uphilile. Sukuyeka ukuthatha i-stiripentol ungakhange uthethe nogqirha wakho, nokuba ngaba uneziphumo ebezingalindelekanga ezinje ngotshintsho olungaqhelekanga kwindlela oziphethe ngayo okanye kwimood. Ukuba ngequbuliso uyeka ukuthatha i-stiripentol, ukubanjwa kwakho kunokuba mandundu. Ugqirha wakho uya kunciphisa umthamo wakho ngokuthe ngcembe.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-stiripentol kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-stiripentol,

  • xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-stiripentol, nawaphi na amanye amayeza, okanye naziphi na izithako kwiipilisi ze-stiripentol okanye i-powder yomlomo yokumiswa. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
  • xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: caffeine okanye amayeza aqukethe icaffeine (Cafcit, Excedrin, eCafergot, abanye); icarbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril); iklopidogrel (iPlavix); diazepam (Valium); glyburide (Diabeta, Glynase); imethotrexate (Otrexup, Rasuvo, Xatmep); imidazolam (Seizalam); phenobarbital; phenytoin (iDilantin, iPhenytek); iprazosin (iMinipress); quinidine (kwiNuedexta); irifampin (Rifadin, Rimactane, eRifamate, eRifater); ukuthomalalisa, iipilisi zokulala, okanye izinto zokuthomalalisa; i-sertraline (iZoloft); i-theophylline (i-Elixophyllin, i-Theo-24, iTochron); thiotepa (Tepadina); okanye i-triazolam (Halcion). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-stiripentol, ke qiniseka ukuxelela ugqirha wakho malunga nawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
  • xelela ugqirha wakho ukuba ukhe wanalo uxinzelelo, iingxaki zemood, okanye iingcinga zokuzibulala okanye isimilo okanye isifo sezintso okanye sesibindi.
  • xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-stiripentol, biza ugqirha wakho.
  • Kuya kufuneka uyazi ukuba i-stiripentol inokukwenza ube nesiyezi okanye uzele kwaye inokuchaphazela ulungelelwaniso lwakho. Musa ukuqhuba imoto okanye usebenzise oomatshini de ube uyazi indlela elikuchaphazela ngayo eli yeza.
  • buza ugqirha wakho malunga nokusetyenziswa okukhuselekileyo kotywala ngelixa uthatha i-stiripentol. Utywala bunokwenza iziphumo ebezingalindelekanga ukuba zibi ngakumbi.
  • ukuba unayo i-phenylketonuria (PKU, imeko ezuzwe njengelifa apho ukutya okukhethekileyo kufuneka kulandelwe ukuthintela ukudodobala kwengqondo), kuya kufuneka wazi ukuba umgubo womlomo we-stiripentol uswiti kunye ne-aspartame eyenza i-phenylalanine.
  • Kuya kufuneka uyazi ukuba impilo yakho yengqondo inokutshintsha ngeendlela ezingalindelekanga kwaye ungazibulala (ucinga ngokuzenzakalisa okanye ukuzibulala okanye ukucwangcisa okanye ukuzama ukwenza njalo) ngelixa uthatha i-stiripentol. Inani elincinci labantu abadala kunye nabantwana abaneminyaka emi-5 ubudala nangaphezulu (malunga ne-1 kubantu abangama-500) abathathe i-anticonvulsants, njenge-stiripentol, ukunyanga iimeko ezahlukeneyo ngexesha lezifundo zeklinikhi baba ukuzibulala ngexesha lonyango lwabo. Abanye baba bantu bakhulise iingcinga zokuzibulala kunye nokuziphatha kwiveki nje enye emva kokuba beqalisile ukuthatha amayeza. Wena kunye nogqirha wakho niya kuthatha isigqibo sokuba ngaba ingozi yokuthatha iyeza le-anticonvulsant inkulu kuneengozi zokungawasebenzisi amayeza. Wena, usapho lwakho, okanye umntu omkhathalelayo kufuneka ubize ugqirha wakho ngoko nangoko ukuba unazo naziphi na kwezi mpawu zilandelayo: uloyiko; ukuphazamiseka okanye ukungazinzi; okutsha okanye ukuhla kokucaphuka, uxinzelelo, okanye uxinzelelo; ukwenza izinto eziyingozi; ubunzima bokuwa okanye ukulala; ndlongondlongo, umsindo okanye ubundlobongela; i-mania (i-frenzied, i-mood engaqhelekanga) ukucinga ngokuzenzakalisa okanye ukuzibulala, okanye ukucwangcisa okanye ukuzama ukwenza njalo; okanye naluphi na olunye utshintsho olungaqhelekanga kwindlela oziphethe ngayo okanye kwimood. Qiniseka ukuba usapho lwakho okanye umntu okhathalelayo uyazi ukuba zeziphi iimpawu ezinokuba nobuzaza ukuze babize ugqirha ukuba awukwazi ukuzifunela unyango ngokwakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.


Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Stiripentol inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

  • ukozela
  • ukudinwa
  • iingxaki ngokulungelelanisa
  • ukushukuma okungalawulekiyo kwilungu lomzimba
  • ukulahleka kwethoni yezihlunu
  • kunzima ukuthetha
  • ukuvuza amathe
  • isicaphucaphu
  • ukugabha
  • utshintsho kubunzima
  • intlungu edibeneyo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

  • ukukhwehlela, umqala obuhlungu, umkhuhlane, ukubanda, okanye ezinye iimpawu zosulelo
  • ukugruzuka okanye ukopha okungaqhelekanga
  • igazi kumchamo okanye ilindle

I-Stiripentol inokubangela ukulahleka kwesidlo kunye nokulahleka kwesisindo. Ukuba uphawula ukuba umntwana wakho uphulukana nobunzima, biza ugqirha wakho.Ugqirha wakho uya kujonga ukukhula komntwana wakho ngononophelo. Thetha nogqirha wakho ukuba unenkxalabo malunga nokukhula komntwana wakho okanye ubunzima xa ethatha la mayeza.


I-Stiripentol inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude {ukukhanya,} ubushushu obugqithisileyo kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-Stiripentol.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

  • KwiNtengiso®
Ukuhlaziywa kokugqibela-12/15/2018

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