I-Calaspargase pegol-mknl Inaliti

Umxholo

• Phambi kokuba ufumane inaliti ye-calaspargase pegol-mknl,
• Inaliti yecalaspargase pegol-mknl inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu biza ugqirha ngokukhawuleza:

I-Calaspargase pegol-mknl isetyenziswa kunye namanye amachiza e-chemotherapy ukunyanga i-leukemia ye-lymphocytic (BONKE; uhlobo lomhlaza weeseli ezimhlophe zegazi) kwiintsana, ebantwaneni nakubantu abadala abancinci abaneminyaka eyi-1 ukuya kwi-21 ubudala. I-Calaspargase pegol-mknl yi-enzyme ephazamisa izinto zendalo eziyimfuneko ekukhuleni kweseli yomhlaza. Isebenza ngokubulala okanye ukuyeka ukukhula kweeseli zomhlaza.

I-Calaspargase pegol-mknl iza njengesisombululo (ulwelo) ukuze ifakwe ngaphakathi ngaphakathi (emthanjeni) ngaphezulu kweyure e-1 ngugqirha okanye ngumongikazi kwiofisi yezonyango okanye esibhedlele. Ihlala inikwa kube kanye kwiiveki ezi-3 ukuba ugqirha ucebisa unyango.

Ugqirha wakho unokufuna ukunciphisa ukunyuswa kwakho, ukulibazisa, okanye ukuyeka unyango lwakho nge-calaspargase pegol-mknl injection, okanye ukunyanga ngamanye amayeza xa uneziphumo ezithile. Qiniseka ukuba uxelela ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho ngecalaspargase pegol-mknl.

I-Calaspargase pegol-mknl inokubangela ukusabela okunobuzaza okanye okusongela ubomi okunokubakho ngexesha lokufakwa okanye ngaphakathi kweyure enye emva kokufakwa. Ugqirha okanye umongikazi uya kukujonga ngexesha lokufakwa kunye neyure enye emva kokuba ukumiliselwa kwakho kugqityiwe ukubona ukuba unempendulo enzulu na kunyango. Xelela ugqirha wakho okanye umongikazi ngokukhawuleza ukuba unazo naziphi na kwezi mpawu zilandelayo: ukudumba kobuso, umqala, ulwimi, imilebe, okanye amehlo; ukugungxula; imihlathi ukurhawuzelela; irhashalala; okanye kunzima ukugwinya okanye ukuphefumla.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Phambi kokuba ufumane inaliti ye-calaspargase pegol-mknl,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-calaspargase pegol-mknl, i-pegaspargase (i-Oncaspar), nawaphi na amanye amayeza, okanye naziphi na izithako kwi-calaspargase pegol-mknl inaliti. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe wanayo na ipancreatitis (ukudumba kwepancreas), amahlwili egazi, okanye ukopha kakhulu, ngakumbi ukuba oku kwenzekile ngexesha lonyango lwangaphambili nge-asparaginase (Elspar), asparaginase erwinia chrysanthemi (Erwinaze) okanye pegaspargase (Oncaspar). Xelela ugqirha wakho ukuba unesifo sesibindi. Ugqirha wakho usenokungafuni ukuba ufumane i-calaspargase pegol-mknl.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Kufuneka uthathe uvavanyo lokukhulelwa ngaphambi kokuba uqale unyango. Akufanele ukhulelwe ngexesha lonyango lwakho ngenaliti ye-calaspargase pegol-mknl inaliti. Kuya kufuneka usebenzise ulawulo lokuzalwa olusebenzayo ukuthintela ukukhulelwa ngexesha lonyango lwakho ngenaliti ye-calaspargase pegol-mknl kunye neenyanga ezi-3 emva kwedosi yakho yokugqibela. ICalaspargase pegol-mknl inokunciphisa ukusebenza kwezinye izinto zokucwangcisa ngomlomo (iipilisi zolawulo lokuzalwa). Kuya kufuneka usebenzise enye indlela yolawulo lokuzalwa ngelixa ufumana eliyeza. Thetha nogqirha wakho ngezinye iindlela zolawulo lokuzalwa eziza kukusebenzela.Ukuba ukhulelwe ngelixa ufumana inaliti ye-calaspargase pegol-mknl, tsalela ugqirha ngokukhawuleza. I-Calaspargase pegol-mknl inokulimaza umbungu.
• xelela ugqirha wakho ukuba uncelisa. Akufanele uncancise ibele ngexesha lonyango lwakho ngenaliti ye-calaspargase pegol-mknl kunye neenyanga ezi-3 emva kwedosi yakho yokugqibela.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Inaliti yecalaspargase pegol-mknl inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• urhudo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu biza ugqirha ngokukhawuleza:

• ukopha okungaqhelekanga okanye ukuqina
• iintlungu eziqhubekayo eziqala kwindawo yesisu, kodwa zinokusasazeka ngasemva
• ukwanda kwenxano, ukuchama rhoqo okanye ukwanda
• ubumthubi besikhumba okanye amehlo; intlungu zesisu; isicaphucaphu; ukugabha; ukudinwa kakhulu; izitulo ezinemibala elula; umchamo omnyama
• intloko ebuhlungu; bomvu, ukudumba, ingalo ebuhlungu okanye umlenze; iintlungu zesifuba; ukuqhawukelwa ngumphefumlo
• ukubetha kwentliziyo okungaqhelekanga okanye okukhawulezayo
• umkhuhlane, ukugodola, ukukhohlela, okanye ezinye iimpawu zosulelo
• ukuphelelwa ngumoya ingakumbi xa usenza umthambo; ukudinwa kakhulu; ukudumba kwemilenze, amaqatha neenyawo; ukubetha kwentliziyo okungaqhelekanga okanye okukhawulezayo

I-Calaspargase pegol-mknl inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwinalaspargase pegol-mknl inaliti.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• I-Asparlas^®