I-Esketamine Nasal Spray

Umxholo

• Ngaphambi kokusebenzisa i-esketamine nasal spray spray,
• I-Esketamine nasal spray spray inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

Sebenzisa i-esketamine impumlo yokutshiza kunokubangela ukuthamba, ukuphelelwa ngamandla, isiyezi, uxinzelelo, imvakalelo yokujikeleza, okanye ukuziva unqanyuliwe emzimbeni wakho, iingcinga, iimvakalelo, indawo kunye nexesha. Uya kusebenzisa i-esketamine nasal spray spray ngokwakho kwiziko lonyango, kodwa ugqirha wakho uya kukubeka esweni ngaphambili, ngexesha, kwaye ubuncinci iiyure ezi-2 emva konyango lwakho. Kuya kufuneka ucwangcise umongi okanye ilungu losapho ukuba likuqhubele ekhaya emva kokusebenzisa i-esketamine. Emva kokusebenzisa i-esketamine nasal spray, musa ukuqhuba imoto, sebenzisa oomatshini, okanye wenze nantoni na apho kufuneka ulumke ngokupheleleyo kude kube lusuku olulandelayo emva kokulala ngokuzolileyo ebusuku. Xelela ugqirha wakho ngoko nangoko ukuba unokudinwa kakhulu, utyhafe, iintlungu esifubeni, ukuphefumla kancinci, intloko ebuhlungu ngequbuliso, ukutshintsha kombono, ukushukuma okungalawulekiyo kwelungu lomzimba, okanye ukuxhuzula.

I-Esketamine inokuba yinto yokwenza umkhwa. Tshela ugqirha wakho ukuba wena okanye nabani na kusapho lwakho uyasela okanye wakha wasela izixa ezikhulu zotywala, wasebenzisa okanye wakha wasebenzisa iziyobisi ezitalatweni, okanye wasebenzisa kakhulu amayeza kagqirha.

Inani elincinci labantwana, ulutsha, kunye nabantu abadala abancinci (ukuya kuthi ga kwi-24 yeminyaka ubudala) abathathe i-anti-depressants ('mood elevators') ngexesha lezifundo zeklinikhi baye bazibulala (becinga ngokuzenzakalisa okanye ukuzibulala okanye ukucwangcisa okanye ukuzama ukwenza njalo). Abantwana, ulutsha, kunye nabantu abadala abancinci abathatha i-anti-depressant ukunyanga uxinzelelo okanye ezinye izifo zengqondo banokuba semngciphekweni wokuzibulala kunabantwana, ulutsha, kunye nabantu abadala abancinci abangazithathiyo ukunyanga ezi meko. Nangona kunjalo, iingcali aziqinisekanga malunga nokuba ungakanani na lo mngcipheko kwaye ingakanani ekufuneka ithathelwe ingqalelo xa usenza isigqibo sokuba ingaba umntwana okanye ulutsha kufuneka athathe i-anti-depressant. Abantwana kufuneka hayi Sebenzisa i-esketamine.

Kuya kufuneka uyazi ukuba impilo yakho yengqondo inokutshintsha ngeendlela ezingalindelekanga xa usebenzisa i-esketamine okanye ezinye i-anti-depressants nokuba sele umdala ngaphezulu kweminyaka eyi-24. Ungazibulala, ngakumbi ekuqaleni konyango lwakho nangalo naliphi na ixesha apho idosi yakho itshintshiwe. Wena, usapho lwakho, okanye umntu omkhathalelayo kufuneka ubize ugqirha wakho ngoko nangoko ukuba unazo naziphi na kwezi mpawu zilandelayo: ukudakumba okutsha okanye okuya kusiba mandundu; ukucinga ngokuzenzakalisa okanye ukuzibulala, okanye ukucwangcisa okanye ukuzama ukwenza njalo; ukukhathazeka kakhulu; ukuphazamiseka; uloyiko; ubunzima bokulala okanye ukulala; indlela yokuziphatha enengcwangu; ukucaphuka; ukwenza ngaphandle kokucinga; ukungazinzi okukhulu; kunye nefrenzied yimincili engaqhelekanga. Qiniseka ukuba usapho lwakho okanye umntu okhathalelayo uyazi ukuba zeziphi iimpawu ezinokuba nobuzaza ukuze babize ugqirha ukuba awukwazi ukuzifunela unyango ngokwakho.

Ngenxa yomngcipheko ngeli chiza, i-esketamine ifumaneka kuphela kwinkqubo ekhethekileyo yokuhambisa. Inkqubo ebizwa ngokuba yiSpravato Risk Evaluation and Mitigation Strategies (REMS). Wena, ugqirha wakho, kunye nekhemesti kufuneka ubhalise kwinkqubo ye-Spravato REMS ngaphambi kokuba ufumane eliyeza. Uya kusebenzisa i-esketamine nasal spray spray kwiziko lonyango phantsi koqwalaselo lukagqirha okanye olunye uqeqesho kwezonyango.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kujonga uxinzelelo lwegazi ngaphambi kwaye ubuncinci iiyure ze-2 emva kokusebenzisa i-esketamine ngalo lonke ixesha.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-esketamine kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (i-FDA) iwebhusayithi okanye iwebhusayithi yomenzi ukuze ufumane isiKhokelo seyeza.

I-Esketamine nasal spray isetyenziswa kunye nenye i-anti-depressant, ethathwe ngomlomo, ukulawula uxinzelelo olunganyangekiyo kunyango (i-TRD; uxinzelelo olungaphuculiyo kunyango) kubantu abadala. Ikwasetyenziswa kunye nolunye uxinzelelo, oluthathwe ngomlomo, ukunyanga iimpawu zoxinzelelo kubantu abadala abanesifo sokudakumba (MDD) kunye neengcinga zokuzibulala okanye izenzo. I-Esketamine ikudidi lwamayeza abizwa ngokuba zii-NMDA receptor antagonists. Isebenza ngokutshintsha umsebenzi wezinto ezithile zendalo kwingqondo.

I-Esketamine iza njengesisombululo (ulwelo) sokutshiza empumlweni. Ukulawulwa koxinzelelo olunganyangekiyo kunyango, kuhlala kufafazwa empumlweni kabini ngeveki phakathi kweeveki ezi-1 ukuya kwezi-4, kube kanye ngeveki phakathi kweeveki ezi-5 ukuya kwezi-8, ze kube kanye ngeveki okanye kube kanye kwiiveki ezi-2 kwiveki yesi-9 nangaphaya. Unyango lweempawu zokudakumba kubantu abadala abanesifo sokudakumba kunye neengcinga zokuzibulala okanye iintshukumo, zihlala zitshizwa ngempumlo kabini ngeveki ukuya kuthi ga kwiiveki ezi-4. I-Esketamine kufuneka isetyenziswe kwiziko lonyango.

Musa ukutya ubuncinci iiyure ezi-2 okanye usele into engamanzi kangangemizuzu engama-30 ngaphambi kokusebenzisa isitshizi seempumlo se-esketamine.

Isixhobo ngasinye sokutshiza ngeempumlo sibonelela ngezifafazi ezi-2 (isitshizi esinye kwithumbu ngalinye) Amachaphaza amabini aluhlaza kwisixhobo akuxelela ukuba isitshizi sempumlo sigcwele, ichaphaza elinye eliluhlaza likuxelela ukuba kusetyenziswe isitshizi esinye, kwaye akukho machaphaza aluhlaza abonisa ukuba kusetyenziswe idosi epheleleyo yezitshizi ezi-2.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa i-esketamine nasal spray spray,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-esketamine, i-ketamine, nawaphi na amanye amayeza, okanye naziphi na izithako kwi-esketamine nasal spray. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: amphetamines, amayeza oxinzelelo, armodafinil (Nuvigil), MAO inhibitors ezinje nge phenelzine (Nardil), procarbazine (Matulane), tranylcypromine (Parnate), kunye selegiline (Eldepryl, Emsam, Zelapar); amanye amayeza okugula ngengqondo, i-methylphenidate (Aptension, Jornay, Metadate, abanye), imodafanil, opioid (narcotic) amayeza entlungu, amayeza okuxhuzula, amayeza okuthomalalisa, iipilisi zokulala, kunye noxinzelelo. Tshela ugqirha wakho ukuba ngaba usandula ukuthatha la mayeza.
• ukuba usebenzisa i-nasal corticosteroid efana ne-ciclesonide (i-Alvesco, i-Omnaris, i-Zetonna) kunye ne-mometasone (i-Asmanex) okanye i-nasal decongestant efana ne-oxymetazoline (Afrin) kunye ne-phenylephrine (i-Neosynephrine), yisebenzise okungenani iyure enye ngaphambi kokusebenzisa i-esketamine nasal spray.
• xelela ugqirha wakho ukuba unesifo semithambo yegazi kwingqondo, esifubeni, kwindawo yesisu, kwiingalo okanye emilenzeni; une-arteriovenous malformation (unxibelelwano olungaqhelekanga phakathi kwemithambo kunye nemithambo); okanye unembali yokopha kwingqondo yakho. Ugqirha wakho uya kukuxelela ukuba ungasebenzisi i-esketamine nasal spray spray.
• xelela ugqirha wakho ukuba ukhe wahlaselwa sistroke, isifo sentliziyo, ukulimala kwengqondo, okanye nayiphi na imeko ebangela ukwanda kwengqondo. Xelela ugqirha wakho ukuba ubona, uziva, okanye uve izinto ezingekhoyo; okanye ukholelwe kwizinto ezingeyonyani. Kwakhona xelela ugqirha wakho ukuba unesifo sentliziyo, ukusilela kwentliziyo, uxinzelelo lwegazi (uxinzelelo oluphezulu lwegazi), ukubetha kwentliziyo kancinci okanye okungaqhelekanga, ukuphefumla kancinci, iintlungu zesifuba, okanye isibindi okanye isifo sentliziyo.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Ukuba ukhulelwa ngelixa usebenzisa i-esketamine nasal spray spray, biza ugqirha ngokukhawuleza. Isitshizi sempumlo se-Esketamine sinokulimaza umbungu.
• xelela ugqirha wakho ukuba uncelisa. Akufanele uncancise ngelixa usebenzisa i-esketamine nasal spray spray.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba usebenzisa i-esketamine nasal spray.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Ukuba uphosa iseshoni yonyango qhagamshelana nogqirha wakho kwangoko ukucwangcisa idinga. Ukuba uluphose unyango kwaye ukudakumba kwakho kusiba kubi, ugqirha wakho kungafuneka atshintshe idosi okanye ishedyuli yonyango.

I-Esketamine nasal spray spray inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• Ukuchama rhoqo, okungxamisekileyo, okutshisayo, okanye okubuhlungu
• ukuqhina
• urhudo
• umlomo owomileyo
• isicaphucaphu
• ukugabha
• kunzima ukucinga okanye ukuziva unxilile
• intloko ebuhlungu
• incasa engaqhelekanga okanye ebuntsimbi emlonyeni
• Ukuphazamiseka kwempumlo
• ukucaphuka komqala
• ukwanda kokubila

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na iimpawu ezidweliswe KWISILUMKISO ESIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olukhawulezileyo.

Isitshizi sempumlo se-Esketamine sinokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa usebenzisa eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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