Inaliti ye-Evinacumab-dgnb

Umxholo

• Ngaphambi kokufumana i-evinacumab-dgnb,
• I-Evinacumab-dgnb inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

I-Evinacumab-dgnb isetyenziswa ngokudibeneyo nolunye unyango ukunciphisa isixa esisezantsi se-lipoprotein (LDL) cholesterol ('cholesterol embi') kunye nezinye izinto ezinamanqatha egazini kubantu abadala nakubantwana abaneminyaka eli-12 ubudala okanye ngaphezulu abane-homozygous Family hypercholesterolemia (HoFH; imeko ezuzwe njengelifa apho i-cholesterol ingenakususwa emzimbeni ngesiqhelo). I-Evinacumab-dgnb ikudidi lwamayeza abizwa ngokuba yi-angiopoietin-like protein 3 (ANGPTL3) inhibitor monoclonal antibodies. Isebenza ngokunciphisa ukuveliswa kwe-cholesterol ye-LDL kunye nokwandisa ukwehla kwe-cholesterol ye-LDL kunye nezinye izinto ezinamanqatha emzimbeni.

Ukuqokelelwa kwecholesterol kunye namafutha ecaleni kweendonga zemithambo yakho (inkqubo eyaziwa njenge-atherosclerosis) inciphisa ukuhamba kwegazi kwaye, ke, unikezelo lweoksijini entliziyweni yakho, kwingqondo nakwamanye amalungu omzimba wakho. Ukunciphisa izinga lakho legazi le-cholesterol kunye namafutha kunokunceda ukukhusela isifo senhliziyo, i-angina (intlungu yesifuba), ukubetha kunye nokuhlaselwa kwentliziyo.

I-Evinacumab-dgnb iza njengesisombululo (ulwelo) sokudityaniswa nolwelo kwaye kutofwe kancinci emthanjeni ngaphezulu kwemizuzu engama-60 ngugqirha okanye ngumongikazi. Ihlala inikwa kube kanye kwiiveki ezi-4.

Inaliti ye-Evinacumab-dgnb inokubangela iimpendulo ezinzulu ngexesha lokufakwa kweyeza. Ugqirha okanye umongikazi uya kukujonga ngononophelo ngelixa ufumana amayeza. Xelela ugqirha wakho okanye umongikazi kwangoko ukuba unazo naziphi na kwezi mpawu zilandelayo ngexesha okanye emva kokufakwa: ukuphefumla kancinci; ukuvutha; irhashalala; imihlathi ukurhawuzelela; isiyezi; ubuthathaka bemisipha; ifiva; isicaphucaphu; ukuxinana kwempumlo; okanye ukudumba kobuso, umqala, ulwimi, imilebe, okanye amehlo.

Ugqirha wakho unokufuna ukunciphisa ukumnika okanye ayeke unyango lwakho ukuba uneziphumo ebezingalindelekanga ezithile. Qiniseka ukuba uxelela ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho nge-evinacumab-dgnb.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana i-evinacumab-dgnb,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-evinacumab-dgnb, nawaphi na amanye amayeza, okanye nasiphi na isithako kwi-evinacumab-dgnb injection. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha.
• xelela ugqirha wakho ukuba ukhulelwe, okanye ucwangcise ukukhulelwa. Kuya kufuneka uthathe uvavanyo lokukhulelwa ngaphambi kokuqala unyango nge-evinacumab-dgnb. Akufanele ukhulelwe ngexesha lonyango lwakho ngenaliti ye-evinacumab-dgnb. Kuya kufuneka usebenzise ulawulo lokuzalwa olusebenzayo ukuthintela ukukhulelwa ngexesha lonyango lwakho ngenaliti ye-evinacumab-dgnb kunye neenyanga ezintlanu emva kwedosi yakho yokugqibela. Ukuba ukhulelwa ngelixa ufumana i-evinacumab-dgnb, biza ugqirha wakho ngokukhawuleza.
• xelela ugqirha wakho ukuba uncelisa.

Yitya ukutya okune-fat-fat, low-cholesterol. Qiniseka ukuba ulandela yonke imithambo kunye nezincomo zokutya ezenziwe ngugqirha wakho okanye ugqirha otya ukutya. Ungandwendwela iNational Cholesterol Education Programme (NCEP) kwiwebhusayithi ukufumana ulwazi olongezelelekileyo malunga nokutya kule dilesi: http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.

Biza ugqirha wakho kwangoko ukuba awukwazi ukugcina ixesha lokuqeshwa ukuze ufumane idosi ye-evinacumab-dgnb inaliti.

I-Evinacumab-dgnb inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• impumlo enemifinya
• ukuxinana kwempumlo
• umqala obuhkungu
• Iimpawu ezinjengomkhuhlane
• umqala obuhkungu
• isiyezi
• isicaphucaphu
• iintlungu emilenzeni nasezingalweni
• ukunciphisa amandla

I-Evinacumab-dgnb inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-evinacumab-dgnb.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Evkeeza^®