IChloroquine

Umxholo

• Ngaphambi kokusebenzisa i-chloroquine phosphate,
• Iziphumo ezivela kwi-chloroquine phosphate zinokwenzeka. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko:
• Iimpawu zokudlula ngaphezulu zinokubandakanya:

I-Chloroquine ifundelwe unyango kunye nokuthintela isifo se-coronavirus 2019 (COVID-19).

I-FDA ivume isigunyaziso sokusetyenziswa okungxamisekileyo (i-EUA) nge-28 ka-Matshi 2020 ukuvumela ukuhanjiswa kwe-chloroquine kubantu abadala abakwishumi elivisayo nabakwishumi elivisayo abanobunzima obuli-110 kg (50 kg) kwaye ngoobani ukulaliswa esibhedlele nge-COVID-19, kodwa abangakwaziyo ukuthatha inxaxheba kuphononongo lweklinikhi. Nangona kunjalo, i-FDA yakurhoxisa oku ngoJuni 15, 2020 kuba izifundo zeklinikhi zabonisa ukuba i-chloroquine ayinakulindeleka ukuba isebenze kunyango lwe-COVID-19 kwezi zigulana kunye nezinye iziphumo ebezingalindelekanga, ezinje ngokubetha kwentliziyo okungaqhelekanga.

I-FDA kunye namaZiko ezeMpilo kaZwelonke (i-NIH) athi i-chloroquine KUFUNEKA isetyenziswe kunyango lwe-COVID-19 phantsi kolwalathiso lukagqirha kwisifundo sezonyango. Sukuthenga la mayeza kwi-Intanethi ngaphandle kommiselo. Ukuba ufumana ukubetha kwentliziyo okungaqhelekanga, isiyezi, okanye ukuphelelwa ngamandla ngelixa uthatha i-chloroquine, tsalela umnxeba ku-911 unyango lonyango olungxamisekileyo. Ukuba uneminye imiphumo emibi, qiniseka ukuxelela ugqirha wakho.

Musa ukuthatha i-chloroquine ejoliswe ngokungqongqo ekusetyenzisweni kwezilwanyana- njengokunyanga iintlanzi kwii-aquariums okanye ukusetyenziswa kwezinye izilwanyana-ukunyanga okanye ukuthintela i-COVID-19. Iingxelo ze-FDA zokuba kwenzakaliswe kakhulu kwaye kusweleke abantu besebenzisa la malungiselelo gwenxa. https://bit.ly/2KpIMcR

I-chloroquine phosphate isetyenziselwa ukuthintela nokunyanga isifo seengcongconi. Isetyenziselwa ukunyanga i-amebiasis. I-chloroquine phosphate ikudidi lweziyobisi ekuthiwa zii-antimalarials kunye ne-amebicides. Isebenza ngokubulala izinto ezibangela isifo seengcongconi kunye ne-amebiasis.

I-chloroquine phosphate iza njengecwecwe lokuthatha ngomlomo. Ukuthintela isifo seengcongconi kubantu abadala, idosi enye ihlala ithathwa kanye ngeveki kanye ngala mini yeveki. Ugqirha wakho uya kukuxelela ukuba zingaphi iipilisi oza kuzithatha kwidosi nganye. Idosi enye ithathwa ekuqaleni kweeveki ezi-2 ngaphambi kokuya kwindawo apho isifo seengcongconi siqhelekile, ngelixa ukule ndawo, kwaye emva kweeveki ezisi-8 emva kokuba ubuyile kuloo ndawo. Ukuba awukwazi ukuqala ukuthatha i-chloroquine kangangeeveki ezi-2 ngaphambi kokuba uhambe, ugqirha wakho usenokukuxelela ukuba uthathe idosi ephindwe kabini ngoko nangoko (kwidosi yokuqala).

Ukunyanga ngesiquphe, uhlaselo olubi lwe-malaria kubantu abadala, idosi enye ihlala ithathwa kwangoko, ilandelwe sisiqingatha sedosi kwiiyure ezi-6 ukuya kwezi-8 kamva kunye nesiqingatha sedosi kube kanye ngemini kwiintsuku ezi-2 ezizayo.

Ukuthintela nokunyanga isifo seengcongconi kwiintsana nasebantwaneni, isixa se-chloroquine phosphate sisekelwe kubunzima bomntwana. Ugqirha wakho uza kubala le mali aze akuxelele ukuba ingakanani ichloroquine phosphate emele ifunyenwe ngumntwana wakho.

Unyango lwe-amebiasis, idosi enye ihlala ithathwa kangangeentsuku ezimbini kunye nesiqingatha sedosi yonke imihla iiveki ezi-2 ukuya kwezi-3. Ihlala ithathwa ngokudityaniswa nezinye ii-amebicides.

IChloroquine phosphate inokubangela isisu esibuhlungu. Thatha i-chloroquine phosphate ngokutya.

Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Sebenzisa i-chloroquine phosphate ngokuchanekileyo njengoko kuyalelwe. Sukuyisebenzisa ngaphezulu okanye ngaphantsi okanye uyisebenzise rhoqo kunokuyalelwa ngugqirha.

I-chloroquine phosphate isetyenziswa ngamanye amaxesha ukunciphisa iimpawu ze-rheumatoid arthritis kunye nokunyanga i-lupic erythematosus, sarcoidosis, kunye ne-porphyria cutanea tarda. Thetha nogqirha wakho malunga neengozi zokusebenzisa eli chiza kwimeko yakho.

La mayeza ngamanye amaxesha amiselweyo kwezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa i-chloroquine phosphate,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uyaliwa yi-chloroquine phosphate, chloroquine hydrochloride, hydroxychloroquine (Plaquenil), okanye ezinye iziyobisi.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qinisekisa ukukhankanya i-acetaminophen (iTylenol, abanye); i-azithromycin (iZithromax); cimetidine (iTagamet); icyclosporine (Gengraf, Neoral, Sandimmune); insulin kunye nomlomo amayeza seswekile; amayeza okubanjwa njenge carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril), phenytoin (Dilantin, Phenytek), okanye i-valproic acid (Depakene); amayeza athile okubetha kwentliziyo ngokungaqhelekanga njenge-amiodarone (Pacerone); imethotrexate (Trexall, Xatmep); moxifloxacin (Avelox); ipraziquantel (iBiltricide); kunye netamoxifen (Nolvadex). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-chloroquine, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owasebenzisayo, nkqu nalawo angaveli kolu luhlu.
• ukuba uthatha ii-antacids, thatha iiyure ezi-4 ngaphambi okanye kwiiyure ezi-4 emva kwe-chloroquine. Ukuba uthatha i-ampicillin, yithathe iiyure ezi-2 ubuncinci ngaphambi okanye kwiiyure ezimbini emva kwe-chloroquine.
• xelela ugqirha wakho ukuba ukhe unesifo sesibindi, isifo sentliziyo, ixesha elide le-QT (ingxaki yentliziyo enqabileyo enokubangela ukubetha kwentliziyo ngokungaqhelekanga, ukubetha, okanye ukufa ngesiquphe), ukubetha kwentliziyo okungaqhelekanga, inqanaba eliphantsi le-magnesium okanye i-potassium igazi lakho, ukusilela kwe-G-6-PD (isifo esifa njengelifa), iingxaki zokuva, i-porphyria okanye ezinye iingxaki zegazi, i-psoriasis, ukuxhuzula, iingxaki zokubona, isifo seswekile, ubuthathaka emadolweni nasemaqatheni, okanye ukuba usela kakhulu utywala.
• xelela ugqirha wakho ukuba wakha wanombono otshintshayo ngelixa uthatha i-chloroquine phosphate, chloroquine hydrochloride, okanye ihydroxychloroquine (Plaquenil).
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Ukuba ukhulelwa ngelixa usebenzisa i-chloroquine phosphate, tsalela umnxeba ugqirha wakho.
• xelela ugqirha wakho ukuba uncelisa okanye ucwangcisa ukuncancisa. I-chloroquine phosphate ingalwenzakalisa usana olunyisayo.
• awunalo ugonyo ngaphandle kokuthetha nogqirha wakho.

Ngaphandle kokuba ugqirha wakho akuyalele ngenye indlela, qhubeka nokutya okuqhelekileyo ngelixa uthatha i-chloroquine phosphate.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

Iziphumo ezivela kwi-chloroquine phosphate zinokwenzeka. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• intloko ebuhlungu
• isicaphucaphu
• Ukuphelelwa ngumdla wokutya
• urhudo
• isisu esimoshakele
• isisu esibuhlungu
• irhashalala
• ukurhawuzelela
• ukulahleka kweenwele

Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko:

• ukubona ukukhanya kunye nokuhamba
• ukungaboni kakuhle
• ukufunda okanye ukubona ubunzima (amagama ayanyamalala, ukubona isiqingatha sento, ukungaboni kakuhle okanye ukungaboni)
• kunzima ukuva
• kukhala ezindlebeni
• ubuthathaka bemisipha
• ukozela
• ukugabha
• ukubetha kwentliziyo okungaqhelekanga
• ukuxhuzula
• ubunzima bokuphefumla
• imo okanye utshintsho lwengqondo
• ukuncipha kwengqondo okanye ukulahleka kwengqondo
• ucinga ngokuzenzakalisa okanye ukuzibulala

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nokukhanya nobushushu obungaphezulu kunye nobumanzi (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

• isicaphucaphu
• ukugabha
• intloko ebuhlungu
• ukozela
• Ukuphazamiseka okubonakalayo
• ukuxhuzula
• ukubetha kwentliziyo ngokungaqhelekanga

Abantwana banolwazelelelo ngakumbi kukudlula, ngenxa yoko gcina amayeza kude nokufikelela kwabantwana.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho unoku-odola uvavanyo oluthile lweelebhu kunye nee-electrocardiograms (EKG, uvavanyo lokujonga ukubetha kwentliziyo yakho kunye nesingqisho) ukujonga impendulo yakho kwi-chloroquine phosphate. Ugqirha wakho uya kuvavanya kwakhona ukuba uza kuba nako na ukubuthathaka kwezihlunu okunokubangelwa sisiyobisi.

Ukuba uthatha i-chloroquine phosphate ixesha elide, ugqirha wakho uza kuncoma uviwo lwamehlo rhoqo. Kubaluleke kakhulu ukuba ugcine ezi zihlandlo. Chloroquine phosphate kunokubangela iingxaki ezinkulu umbono. Ukuba ufumana naluphi na utshintsho kumbono, yeka ukuthatha i-chloroquine phosphate kwaye ubize ugqirha ngoko nangoko.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• UAralen^®¶

^¶ Le mveliso inophawu akusekho kwimarike. Ezinye iindlela ezinokubakho zinokubakho.