Tamoxifen

Umxholo

• Ngaphambi kokuba uthathe i-tamoxifen,
• I-Tamoxifen inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:
• Iimpawu zokudlula ngaphezulu zinokubandakanya:

I-Tamoxifen inokubangela umhlaza wesibeleko (isibeleko), imivumbo, kunye namahlwili egazi emiphungeni. Ezi meko zinokuba zibi okanye zibulale. Tshela ugqirha wakho ukuba ukhe waba negazi emiphungeni okanye emilenzeni, icala, okanye isifo sentliziyo. Xelela ugqirha wakho ukuba uyatshaya, ukuba unoxinzelelo oluphezulu lwegazi okanye isifo seswekile, ukuba amandla akho okuhamba-hamba ngexesha lokuvuka kwakho anqunyelwe, okanye ukuba uthatha ii-anticoagulants ('thinner') ezinjenge-warfarin (Coumadin). Ukuba ufumana naziphi na kwezi mpawu zilandelayo ngexesha okanye emva konyango lwakho, tsalela umnxeba kwangoko: ukopha ngokungaqhelekanga kwilungu lobufazi; amaxesha okungaqhelekanga okuya exesheni; utshintsho kuphuma kwilungu lobufazi, ngakumbi ukuba ukubhobhoza kuba ligazi, brown, okanye umhlwa; iintlungu okanye uxinzelelo kwi-pelvis (indawo yesisu engezantsi kweqhosha lesisu); ukudumba komlenze okanye ukuthamba; iintlungu zesifuba; ukuqhawukelwa ngumphefumlo; ukukhohlela igazi; ubuthathaka ngequbuliso, ukubetha, okanye ukuba ndindisholo ebusweni bakho, ingalo, okanye umlenze, ngakumbi kwelinye icala lomzimba wakho; ukudideka ngesiquphe; kunzima ukuthetha okanye ukuqonda; ubunzima ngesiquphe kwamehlo omnye okanye omabini; ukuhamba ngesiquphe; isiyezi; ukulahleka kwemali eseleyo okanye yokulungelelanisa; okanye intloko ebuhlungu ngesiquphe.

Gcina lonke ixesha lokudibana nogqirha wakho. Kuya kufuneka ukuba ube neemviwo zesibeleko (iimviwo kwizitho zabasetyhini) rhoqo ukufumana iimpawu zokuqala zomhlaza wesibeleko.

Ukuba ucinga ngokuthatha i-tamoxifen ukunciphisa amathuba okuba ube nomhlaza webele, kuya kufuneka uthethe nogqirha wakho malunga neengozi kunye nezibonelelo zonyango. Wena kunye nogqirha wakho uya kuthatha isigqibo sokuba ngaba uncedo lwonyango lwe-tamoxifen lufanelekile ingozi yokuthatha iyeza. Ukuba ufuna ukuthatha i-tamoxifen ukunyanga umhlaza webele, izibonelelo ze-tamoxifen zingaphezulu komngcipheko.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seMithi) xa uqala unyango nge-tamoxifen kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

I-Tamoxifen isetyenziselwa ukunyanga umhlaza wamabele osasazeke kwamanye amalungu omzimba kumadoda nabasetyhini. Isetyenziselwa ukunyanga umhlaza webele kwangoko kubafazi abasele bephathwe ngotyando, ngemitha kunye / okanye ngechemotherapy. Isetyenziselwa ukunciphisa umngcipheko wokuphuhlisa uhlobo olubi kakhulu lomhlaza wamabele kwabasetyhini abaye baneductal carcinoma in situ (DCIS; uhlobo lomhlaza wamabele olungasasazeki ngaphandle kwendlela yobisi apho lwenza khona) kwaye ngubani waphathwa ngotyando kunye nemitha. Isetyenziselwa ukunciphisa umngcipheko womhlaza wamabele kwabasetyhini abasemngciphekweni omkhulu wesifo ngenxa yobudala babo, imbali yezonyango kunye nembali yonyango yosapho.

I-Tamoxifen ikudidi lwamayeza abizwa ngokuba yi-antiestrogens. Ibhloka umsebenzi we-estrogen (ihomoni yabasetyhini) ebeleni. Oku kunokumisa ukukhula kwamanye amathumba ebele afuna i-estrogen ukuba ikhule.

I-Tamoxifen iza njengecwecwe lokuthatha ngomlomo. I-Tamoxifen ihlala ithathwa kanye okanye kabini ngosuku kunye okanye ngaphandle kokutya. Thatha i-tamoxifen malunga nexesha elifanayo (ii) yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nantoni na ongayiqondiyo. Thatha i-tamoxifen ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya iipilisi ze-tamoxifen ziphelele; ungahluleli, ungahlaleli, okanye uzityumze. Ginya iipilisi ngamanzi okanye nasiphi na isiselo esinxilisayo.

Ukuba uthatha i-tamoxifen ukukhusela umhlaza webele, uya kuyithatha iminyaka emihlanu. Ukuba uthatha i-tamoxifen ukunyanga umhlaza webele, ugqirha wakho uya kuthatha isigqibo sokuba unyango lwakho luya kuhlala lude kangakanani. Ungayeki ukuthatha i-tamoxifen ngaphandle kokuthetha nogqirha wakho.

Ukuba ulibale ukuthatha idosi ye-tamoxifen, thabatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule, kwaye uthathe idosi yakho elandelayo njengesiqhelo. Nangona kunjalo, ukuba phantse lixesha ledosi yakho elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yedosi. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Tamoxifen ikwasetyenziselwa ngamanye amaxesha ukwenza i-ovulation (ukuveliswa kweqanda) kwabasetyhini abangavelisi amaqanda kodwa banqwenela ukukhulelwa. I-Tamoxifen ngamanye amaxesha isetyenziselwa ukunyanga iMcCune-Albright syndrome (MAS; imeko enokubangela isifo samathambo, ukukhula ngokwesondo kwangoko, kunye namabala amnyama esikhumbeni ebantwaneni). Thetha nogqirha wakho malunga neengozi zokusebenzisa eli chiza kwimeko yakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-tamoxifen,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-tamoxifen okanye amanye amayeza.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zilandelayo: aminoglutethimide (Cytadren); anastrozole (Arimidex), bromocriptine (Parlodel); umhlaza amayeza e-chemotherapy afana ne-cyclophosphamide (Cytoxan, Neosar) letrozole (Femara); I-medroxyprogesterone (iDepo-Provera, iProvera, kwi-Prempro); phenobarbital; Kunye nerifampin (Rifadin, Rimactane). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• ukongeza kwezi meko zidweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO, xelela ugqirha wakho ukuba ukhe waba namanqanaba aphezulu egazi echolesterol.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Akufanele ucwangcise ukukhulelwa ngelixa uthatha i-tamoxifen okanye iinyanga ezimbini emva konyango lwakho. Ugqirha wakho angenza uvavanyo lokukhulelwa okanye akuxelele ukuba uqale unyango lwakho ngexesha lokuya esikhathini ukuze uqiniseke ukuba awukhulelwe xa uqala ukuthatha i-tamoxifen. Kuya kufuneka usebenzise indlela ethembekileyo yokulawula ukuzalwa ukuthintela ukukhulelwa ngelixa uthatha i-tamoxifen kunye neenyanga ezi-2 emva konyango lwakho. Thetha nogqirha wakho malunga neentlobo zolawulo lokuzalwa ezifanelekileyo kuwe, kwaye uqhubeke nokusebenzisa ulawulo lokuzalwa nokuba awunaxesha lokuya exesheni rhoqo ngexesha lonyango lwakho. Yeka ukuthatha i-tamoxifen kwaye ubize ugqirha wakho ngoko nangoko ukuba ucinga ukuba ukhulelwe ngexesha lonyango lwakho. I-Tamoxifen inokulimaza umbungu.
• xelela ugqirha wakho ukuba uncelisa. Akufanele uncelise ngexesha lonyango lwakho nge-tamoxifen.
• xelela bonke oogqirha bakho kunye nabanye ababoneleli ngezempilo ukuba uthatha i-tamoxifen.
• Uya kudinga ukujonga iimpawu zokuqala zomhlaza wamabele kuba kunokwenzeka ukuba uphuhlise umhlaza wamabele nokuba kunyango lwe-tamoxifen. Thetha nogqirha wakho malunga nokuba kufuneka uwavavanye kangaphi amabele akho, ugqirha akuvavanye amabele, kwaye uneemammograms (iimviwo ze-x-ray zamabele). Biza ugqirha wakho ngoko nangoko ukuba ufumana iqhuma elitsha ebeleni lakho.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Tamoxifen inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukonyuka kwethambo okanye ithumba
• iintlungu okanye ubomvu kwakhona kwindawo yethumba
• kushushu
• isicaphucaphu
• ukudinwa kakhulu
• isiyezi
• ukudakumba
• intloko ebuhlungu
• ukucheba kweenwele
• ukuhla ukusinda
• isisu esiswini
• ukuqhina
• Ukuphulukana nomnqweno wesini okanye amandla (emadodeni)

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:

• iingxaki zombono
• Ukuphelelwa ngumdla wokutya
• mthubi ulusu okanye amehlo
• ukugruzuka okanye ukopha okungaqhelekanga
• ifiva
• amadyungudyungu
• irhashalala
• ukudumba kwamehlo, ubuso, imilebe, ulwimi, umqala, izandla, iingalo, iinyawo, amaqatha okanye imilenze esezantsi
• unxano
• ubuthathaka bemisipha
• ukungazinzi

I-Tamoxifen inokunyusa umngcipheko wokuba uphuhlise eminye imihlaza, kubandakanya nomhlaza wesibindi. Thetha nogqirha wakho malunga nale ngozi.

I-Tamoxifen inokunyusa umngcipheko wokuba uza kuphuhlisa i-cataract (ukugcwala kwelensi esweni) enokufuna ukunyangwa ngotyando. Thetha nogqirha wakho malunga nale ngozi.

I-Tamoxifen inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Gcina i-tamoxifen kwisitya engene ngayo, ivaliwe ngokuqinileyo, kwaye ayifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

• ukushukuma okungalawulekiyo kwilungu lomzimba
• ukungazinzi
• isiyezi

• Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-tamoxifen.
• Ngaphambi kokuba uvavanywe elebhu, xelela ugqirha wakho kunye nabasebenzi baselebhu ukuba uthatha i-tamoxifen.
• Musa ukuvumela nabani na ukuba athathe amayeza akho. Thetha kumachiza wakho ukuba unemibuzo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• INolvadex^®
• Soltamox^®¶

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