Imercaptopurine

Umxholo

• Ngaphambi kokuba uthathe i-mercaptopurine,
• IMercaptopurine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:
• Iimpawu zokudlula ngaphezulu zinokubandakanya:

I-Mercaptopurine isetyenziswa yodwa okanye nezinye iziyobisi ze-chemotherapy ukunyanga i-leukemia ye-lymphocytic (YONKE; ikwabizwa ngokuba yi-acute lymphoblastic leukemia kunye ne-acute lymphatic leukemia; uhlobo lomhlaza oqala kwiiseli ezimhlophe zegazi). IMercaptopurine ikwiklasi yamayeza abizwa ngokuba zii-purine antagonists. Isebenza ngokumisa ukukhula kweeseli zomhlaza.

IMercaptopurine iza njengecwecwe kunye nokumiswa (ulwelo) ukuthatha ngomlomo. Ihlala ithathwa kanye ngemini. Thatha i-mercaptopurine malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-mercaptopurine ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ukuba uthatha ukunqunyanyiswa, yigungqise kakuhle ibhotile kangangemizuzwana engama-30 ngaphambi kokuba uyisebenzise ngokudibanisa amayeza ngokulinganayo. Kubalulekile ukusebenzisa isirinji yomlomo (isixhobo sokulinganisa) ukulinganisa ngokuchanekileyo kwaye uthathe idosi yakho ye-mercaptopurine. Ukuba awuyifumani isirinji yomlomo kunye neyeza lakho, cela usokhemesti wakho akunike. Emva kokusebenzisa isirinji yomlomo ukuthatha iyeza lakho, susa isixhobo sokulinganisa kuso sonke isixhobo sokulinganisa, hlamba zombini iindawo ngamanzi ashushu anesepha, kwaye uhlambe phantsi kwamanzi aphuma empompini. Vumela iindawo ukuba zome umoya ngaphambi kokuba zibuyiselwe ukusetyenziswa kwakhona.

Qhubeka nokuthatha i-mercaptopurine nokuba uziva uphilile. Sukuyeka ukuthatha i-mercaptopurine ngaphandle kokuthetha nogqirha wakho

I-Mercaptopurine ngamanye amaxesha isetyenziselwa ukunyanga ezinye iintlobo zomhlaza, isifo sikaCrohn (imeko apho umzimba uhlasela ulwelo lwendlela yokugaya ebangela iintlungu, urhudo, ukwehla kobunzima, kunye nomkhuhlane), kunye nesilonda esibuhlungu (isifo apho izilonda zikhula khona. emathunjini abangela iintlungu kunye norhudo). Thetha nogqirha wakho malunga neengozi zokusebenzisa la mayeza kwimeko yakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-mercaptopurine,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-mercaptopurine, nawaphi na amanye amayeza, okanye naziphi na izithako kwiipilisi ze-mercaptopurine okanye ukumiswa. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: allopurinol (Lopurin, Zyloprim); ii-aminosalicylates ezinje nge-mesalamine (Apriso, Asacol, Canasa, Lialda, Delzicol, Pentasa, abanye), olsalazine (Dipentum), kunye ne-sulfasalazine (Azulfidine); ii-anticoagulants (’izinciphisi zegazi’) ezifana ne-warfarin (Coumadin, Jantoven); doxorubicin (Doxil); kunye ne-trimethoprim kunye ne-sulfamethoxazole (Bactrim, Septra). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba sele uthathe i-mercaptopurine okanye i-thioguanine ukunyanga umhlaza wakho.Ugqirha wakho unokukuxelela ukuba ungathathi i-mercaptopurine ukuba elinye lala mayeza belingasebenzi kakuhle kumhlaza wakho ngaphambili.
• xelela ugqirha wakho ukuba ngaba unalo naluphi na uhlobo losulelo kwaye ukuba ukhe unesifo sesibindi okanye sezintso.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Kuya kufuneka usebenzise ulawulo lokuzalwa ukuthintela ukukhulelwa ngexesha lonyango lwakho nge-mercaptopurine. Ukuba ukhulelwe ngelixa uthatha i-mercaptopurine, tsalela ugqirha ngokukhawuleza. IMercaptopurine inokwenzakalisa umntwana ongekazalwa.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-mercaptopurine.
• awunalo ugonyo ngaphandle kokuthetha nogqirha wakho.
• Kuya kufuneka uyazi ukuba umngcipheko wokuba uza kuba neziphumo ebezingalindelekanga ze-mercaptopurine unokuphakama xa unemfuza. Ugqirha wakho unoku-odola uvavanyo ngaphambi okanye ngexesha lonyango lwakho ukuze abone ukuba unalo mngcipheko.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

IMercaptopurine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• ubumnyama besikhumba
• ukulahleka kweenwele
• irhashalala

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

• ulusu oluthuthu
• ubuthathaka
• ukuqhawukelwa ngumphefumlo
• umqala obuhlungu, umkhuhlane, ukugodola, okanye ezinye iimpawu zosulelo
• ukudumba emilenzeni, emaqatheni, okanye ezinyaweni
• ukugruzuka okanye ukopha okungaqhelekanga
• mthubi ulusu okanye amehlo
• Ukuphelelwa ngumdla wokutya
• urhudo
• ukudumba kwesisu
• iintlungu kwinxalenye ephezulu yesisu

Ukuthatha i-mercaptopurine kunokunyusa umngcipheko wokuba ube nomhlaza omtsha. Abanye abantu abathathe i-mercaptopurine ukunyanga isifo sikaCrohn okanye isifo sezilonda ezenziwa sisilonda sikabhobhosi baphuhlisa i-hepatosplenic T cell lymphoma (HSTCL), uhlobo lomhlaza olubi kakhulu oludla ngokubulala ngexesha nje elifutshane. Xelela ugqirha wakho ukuba unazo naziphi na kwezi mpawu zilandelayo: iintlungu esiswini; ifiva; ukwehla kobunzima obungachazwanga; ukubila ebusuku okanye ukugruzuka ngokulula okanye ukopha. Thetha nogqirha wakho malunga nemingcipheko yokuthatha la mayeza.

IMercaptopurine inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Ukumiswa kweMercaptopurine kunokugcinwa kubushushu begumbi ukuya kuthi ga kwiiveki ezi-6 emva kokuba ibhotile ivuliwe okokuqala. Emva koko, lahla nakuphi na ukunqunyanyiswa okuseleyo emva kweeveki ezi-6.

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

• Ukuphelelwa ngumdla wokutya
• isicaphucaphu
• ukugabha
• urhudo
• ulusu oluthuthu
• ubuthathaka
• ukuqhawukelwa ngumphefumlo
• umqala obuhlungu, umkhuhlane, ukubanda, kunye neminye imiqondiso yosulelo
• ukugruzuka okanye ukopha okungaqhelekanga

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-mercaptopurine.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• IPurinethol^®
• IPurixan^®

• 6-MP