Inaliti yeGranisetron

Umxholo

• Ngaphambi kokusebenzisa inaliti yegranisetron,
• Inaliti yeGranisetron inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko okanye ufune unyango olungxamisekileyo:
• Iimpawu libanda kungaquka oku kulandelayo:

Inaliti yokukhutshwa kwangoko kweGranisetron isetyenziselwa ukuthintela isicaphucaphu kunye nokugabha okubangelwa ngumhlaza chemotherapy kunye nokuthintela nokunyanga isicaphucaphu kunye nokugabha okunokwenzeka emva kotyando. Inaliti ye-Granisetron eyandisiweyo-yokukhulula (esebenza ixesha elide) isetyenziswa namanye amayeza ukuthintela isicaphucaphu kunye nokugabha okubangelwa ngumhlaza chemotherapy onokuthi uvele kwangoko okanye kwiintsuku ezimbalwa emva kokufumana amayeza e-chemotherapy. IGranisetron ikudidi lwamayeza abizwa ngokuba yi-5-HT₃ abachasi be-receptor. Isebenza ngokuthintela i-serotonin, into yendalo emzimbeni ebangela isicaphucaphu nokugabha.

Inaliti yokukhutshwa kwangoko kweGranisetron iza njengesisombululo (ulwelo) sokujova ngaphakathi (emthanjeni) kunye nenaliti yokukhululwa eyandisiweyo yegranisetron iza njengamanzi aza kufakwa ngaphakathi (phantsi kolusu). Ukuthintela isicaphucaphu kunye nokugabha okubangelwa ngumhlaza chemotherapy, i-granisetron ekhutshwa kwangoko kunye nenaliti yokukhupha eyandisiweyo ihlala inikezelwa ngumboneleli wezempilo esibhedlele okanye ekliniki kwisithuba semizuzu engama-30 ngaphambi kokuqala kwekhemotherapy. Ukuthintela isicaphucaphu kunye nokugabha okubangelwa luqhaqho, ukukhutshwa ngokukhawuleza kwegranisetron kuhlala kunikwa ngexesha lotyando. Ukunyanga isicaphucaphu kunye nokugabha okubangelwa lutyando, igranisetron inikwa msinyane nje ukuba isicaphucaphu nokugabha kwenzeke.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa inaliti yegranisetron,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana negranisetron, alosetron (Lotronex), dolasetron (Anzemet), ondansetron (Zofran, Zuplenz), palonosetron (Aloxi, eAkynzeo), nawaphi na amanye amayeza, okanye naziphi na izithako kwiinaliti yegranisetron. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zilandelayo: amiodarone (Cordarone, Nexterone, Pacerone); azithromycin (Zithromax), chlorpromazine, citalopram (Celexa); i-clarithromycin (i-Biaxin, kwi-Prevpac); i-erythromycin (EES, ERYC, Erythrocin, nabanye); fentanyl (Abstral, Actiq, Duragesic, Fentora, Lazanda, Subsys); ketoconazole (Nizoral); lithium (Lithobid); amayeza iingxaki zentliziyo; amayeza okunyanga i-migraines efana ne-almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex, eTreximet), kunye ne-zolmitriptan (iZomig); i-mirtazapine (iRemeron); i-monoamine oxidase (MAO) inhibitors kubandakanya isocarboxazid (Marplan), imethylene eluhlaza okwesibhakabhaka; linezolid (Zyvox), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), kunye ne-tranylcypromine (iParnate); moxifloxacin (Avelox); ipimozide (Orap); phenobarbital; i-serotonin reuptake inhibitors (i-SSRIs) ekhethiweyo njenge-citalopram (i-Celexa), i-escitalopram (i-Lexapro), i-fluoxetine (i-Prozac, i-Sarafem, kwi-Symbyax, abanye), i-fluvoxamine (i-Luvox), i-paroxetine (i-Brisdelle, i-Paxil, i-Pexeva) kunye ne-sertraline (i-Zoloft ; i-serotonin-norepinephrine reuptake inhibitors (SNRI) yeyeza desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), levomilnacipran (Fetzima), kunye ne-venlafaxine; i-sotalol (iBetapace, iSorine); thioridazine; kunye ne-tramadol (Conzip, Ultram, kwi-Ultracet). Ukuba ufumana inaliti yokukhululwa eyandisiweyo, xelela ugqirha wakho ukuba uthatha ii-anticoagulants ('blood thinner') ezifana ne-warfarin (Coumadin, Jantoven); amayeza antiplatelet anje nge cilostazol, clopidogrel (Plavix), dipyridamole (Persantine, e Aggrenox), prasugrel (Effient), okanye ticlopidine. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akujonge ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana negranisetron, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba usandula ukwenza utyando lwesisu okanye ukuqhina. Kwakhona xelela ugqirha wakho ukuba wena okanye omnye umntu kusapho lwakho une-QT syndrome (imeko eyonyusa umngcipheko wokuba nesifo sentliziyo esingaqhelekanga esinokubangela ukuba utyhafile okanye usweleke ngesiquphe), olunye uhlobo lokubetha kwentliziyo okungaqhelekanga okanye ingxaki yesingqisho sentliziyo, ukungalingani kwe-electrolyte, okanye izintso okanye isifo senhliziyo.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwe ngelixa usebenzisa inaliti yegranisetron, tsalela ugqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Inaliti yeGranisetron inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• intloko ebuhlungu
• ukuqhina
• ubunzima bokulala okanye ukulala

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko okanye ufune unyango olungxamisekileyo:

• urhwebo
• irhashalala
• ukugungxula
• ukurhawuzelela
• ubunzima bokuphefumla okanye ukugwinya
• ukuqhawukelwa ngumphefumlo
• ukudumba kwamehlo, ubuso, umlomo, ulwimi, okanye umqala
• iintlungu zesifuba
• ububomvu besiza senaliti, ukudumba, okanye ukufudumala kunye okanye ngaphandle komkhuhlane (ngenaliti eyandisiweyo)
• ukopha kwindawo yenaliti, ukutyumka, okanye iintlungu (ngenaliti eyandisiweyo)
• indawo yesisu okanye ukudumba
• isiyezi, intloko ebuthathaka, nokufa isiqaqa
• utshintsho kwintliziyo
• ukuphazamiseka, ukubona izinto ezingekhoyo (ukubona izinto okanye ukuva amazwi angabikho). utshintsho kwimeko yengqondo, okanye i-coma (ukulahleka kwengqondo)
• ukungcangcazela, ukulahleka kokudibana, okanye ukuqina okanye izihlunu ezijijekileyo
• ifiva
• ukubila okugqithisileyo
• ukudideka
• isicaphucaphu, ukugabha kunye norhudo
• ukuxhuzula

Inaliti yeGranisetron inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa usebenzisa eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• intloko ebuhlungu

Gcina lonke ixesha lokudibana nogqirha wakho.

Ngaphambi kokuba uvavanywe elebhu (ngakumbi ezo zibandakanya imethylene eluhlaza okwesibhakabhaka), xelela ugqirha wakho kunye nabasebenzi baselebhu ukuba ufumana inaliti yegranisetron.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• ISustol^®