Umbhali: William Ramirez
Umhla Wokudalwa: 22 Eyomsintsi 2021
Hlaziya Umhla: 13 Eyenkanga 2024
Anonim
Gold-stavudine-PLGA nanoparticles - Video abstract: 38013
Ividiyo: Gold-stavudine-PLGA nanoparticles - Video abstract: 38013

Umxholo

I-Stavudine inokubangela ukuba i-lactic acidosis eyingozi okanye esongela ubomi (ukwakha i-asidi egazini) enokuthi inyanzeleke ukuba inyangwe esibhedlele. Umngcipheko wokuba uza kuphuhlisa i-lactic acidosis iphezulu ukuba ungumfazi, ukuba utyebe kakhulu, kwaye ukuba uye wanyangwa ngamayeza kwi-virus ye-immunodeficiency virus (HIV) ixesha elide. Umngcipheko unokuphakama ukuba ukhulelwe kwaye uthatha i-stavudine kunye ne-didanosine (Videx). Tshela ugqirha wakho ukuba ukhe unesifo sesibindi, kubandakanya usulelo lwentsholongwane ye-hepatitis C. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, biza ugqirha ngokukhawuleza: isicaphucaphu; ukugabha; ukuphelelwa ngumdla wokutya; ukudinwa okugqithisileyo; ubuthathaka; isiyezi; intloko emhlophe; ukukhawuleza kwentliziyo okanye okungaqhelekanga; ingxaki yokuphefumla; umchamo omnyama omthubi okanye omdaka; ukopha okungaqhelekanga okanye ukugruzuka; iimpawu ezifana nomkhuhlane; ukukhanya okukhanyayo; ubumthubi besikhumba okanye amehlo; iintlungu kwindawo ephezulu yesisu sakho; ukuziva ubanda, ngakumbi ezingalweni okanye emilenzeni; okanye iintlungu zemisipha ezahlukileyo kunayo nayiphi na intlungu yesihlunu oqhele ukuba nayo.


I-Stavudine inokubangela ukudumba kwentliziyo okunamandla okanye okusongela (ukudumba kwepancreas). Xelela ugqirha wakho ukuba uyasela okanye wakha wasela izixa ezikhulu zeziselo ezinxilisayo nokuba ukhe wanaso na isifo sokudumba kwentliziyo. Musa ukusela utywala ngelixa uthatha istavudine. Xelela ugqirha wakho ukuba uthatha i-didanosine (Videx). Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko: iintlungu zesisu okanye ukudumba, isicaphucaphu, ukugabha, okanye umkhuhlane.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile ukujonga impendulo yomzimba wakho kwi-stavudine.

Thetha nogqirha wakho malunga neengozi zokuthatha istavudine.

I-Stavudine isetyenziswa kunye namanye amayeza ukunyanga intsholongwane kaGawulayo. UStavudine ukwiklasi yamayeza abizwa ngokuba yi-nucleoside reverse transcriptase inhibitors (NRTIs). Isebenza ngokunciphisa inani le-HIV egazini. Nangona i-stavudine ingayinyangi i-HIV, inokuwehlisa amathuba okuba ube ne-immunodeficiency syndrome (i-AIDS) kunye nezifo ezinxulumene ne-HIV ezinje ngezifo ezomeleleyo okanye umhlaza. Ukuthatha la mayeza kunye nokwabelana ngesondo okukhuselekileyo nokwenza olunye utshintsho kwindlela yokuphila kunokunciphisa umngcipheko wokuhambisa (ukusasaza) intsholongwane kagawulayo kwabanye abantu.


I-Stavudine iza njengecapsule kunye nesisombululo somlomo (ulwelo) sokuyithatha ngomlomo. Ihlala ithathwa kabini ngemini (rhoqo emva kweeyure ezili-12), kunye okanye ngaphandle kokutya kunye namanzi amaninzi. Ukukunceda ukhumbule ukuthatha i-stavudine, yithathe ngamaxesha afanayo mihla le. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-stavudine kanye njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ukuba unika isisombululo somlomo emntwaneni, yigungqise kakuhle ibhotile ngaphambi kokuba uyisebenzise ukudibanisa amayeza ngokulinganayo. Sebenzisa ikomityi yokulinganisa enikezelwe ukulinganisa idosi yomntwana.

UStavudine ulawula usulelo lwe-HIV kodwa akalunyangi. Qhubeka nokuthatha i-stavudine nokuba uziva uphilile. Sukuyeka ukuthatha i-stavudine ungakhange uthethe nogqirha wakho. Xa ubonelelo ngestavudine luqala ukuba phantsi, fumana ngakumbi kugqirha okanye kwikhemesti. Ukuba uphosa idosi okanye ngequbuliso uyeke ukuthatha i-stavudine, imeko yakho kunokuba nzima ngakumbi ukuyinyanga.


I-Stavudine ngamanye amaxesha isetyenziswa ngokudibanisa namanye amayeza ukuthintela usulelo lwe-HIV kubasebenzi bokhathalelo lwempilo okanye abanye abantu abaye bavezwa ngengozi yi-HIV. Thetha nogqirha wakho malunga neengozi zokusebenzisa la mayeza kwimeko yakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuthatha istavudine,

  • xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-stavudine, nawaphi na amanye amayeza, okanye nasiphi na isithako esikwiifapsules zestavudine okanye isisombululo somlomo. Buza usokhemesti wakho uluhlu lwezithako okanye ujonge isikhokelo sonyango.
  • xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo kunye neemveliso zamayeza owathathayo. Qiniseka ukuba ukhankanya abo badweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO kunye ne-doxorubicin, i-hydroxyurea (iDroxia, iSiklos), i-ribavirin (iRebetol, iRibasphere), okanye i-zidovudine (i-Retrovir, kwi-Combivir, kwi-iTizivirir). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akujonge ngononophelo kwiziphumo ebezingalindelekanga.
  • xelela ugqirha wakho ukuba ufumana unyango lwe-dialysis okanye ukuba unesifo sezintso, isifo seswekile, okanye i-peripheral neuropathy (uhlobo lomonakalo wemithambo ebangela ukurhawuzelela, ukuba ndindisholo, kunye nentlungu ezandleni nasezinyaweni).
  • xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba uyakhulelwa ngelixa uthatha istavudine, tsalela umnxeba ugqirha wakho. Akufuneki uncancise xa wosulelwe yi-HIV okanye ukuba uthatha istavudine.
  • Kuya kufuneka uyazi ukuba i-stavudine inokubangela iziphumo ebezingalindelekanga ekufuneka zinyangwe kwangoko ngaphambi kokuba zibe mandundu. Abantwana abathatha istavudine basenokungakwazi ukukuxelela ngeziphumo ebezingalindelekanga abazivayo. Ukuba unika umntwana i-stavudine, buza ugqirha womntwana ukuba unokwazi njani ukuba umntwana unale miphumela emibi.
  • Kuya kufuneka uyazi ukuba unokulahleka kwamanqatha omzimba ebusweni bakho, imilenze, kunye neengalo. Thetha nogqirha wakho ukuba uyalubona olu tshintsho.
  • Kuya kufuneka uyazi ukuba ngelixa uthatha amayeza ukunyanga usulelo lwe-HIV, amajoni akho omzimba angomelela kwaye aqale ukulwa nezinye izifo ezazisele zisemzimbeni wakho. Oku kunokubangela ukuba ube neempawu zolu sulelo. Ukuba uneempawu ezintsha okanye eziba mandundu emva kokuqala unyango nge-stavudine, qiniseka ukuxelela ugqirha wakho.
  • ukuba unesifo seswekile, kuya kufuneka wazi ukuba kukho i-50 mg ye-sucrose kwitispuni nganye (5 ml) yesisombululo somlomo se-stavudine.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Stavudine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba enye yezi mpawu inzima okanye ayihambi:

  • intloko ebuhlungu
  • urhudo
  • irhashalala

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana ezi mpawu zilandelayo okanye nayiphi na kwezi zidweliswe kwicandelo LESILumkiso ESIBALULEKILEYO, tsalela ugqirha wakho ngokukhawuleza:

  • ukuba ndindisholo, ukurhawuzelela, ukutshisa okanye iintlungu ezandleni okanye ezinyaweni
  • ubunzima bokuhambisa izandla neenyawo

I-Stavudine inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Gcina iifomsile kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Gcina isisombululo somlomo kwifriji kwaye ulahle icandelo elingasetyenziswanga emva kweentsuku ezingama-30.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

  • ukuba ndindisholo, ukurhawuzelela, ukuba buthathaka, okanye iintlungu ezandleni okanye ezinyaweni
  • ukugabha
  • iintlungu zesisu ezingaqhelekanga okanye ezingalindelekanga
  • ubuthathaka okanye ukudinwa
  • ukuqhawukelwa ngumphefumlo

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Gcina unikezelo lwe-stavudine ezandleni zakho. Sukulinda de uphelelwe ngamayeza ukuze uphinde uzalise amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

  • Zerit®
  • d4T
Ukuhlaziywa kokugqibela-05/15/2018

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