Ifrile neutropenia: yintoni, unobangela kunye nonyango

Umxholo

• Oonobangela febrile neutropenia
• Unjani unyango

Ifrile neutropenia inokuchazwa njengokwehla kwenani lee-neutrophils, ukufunyanwa kuvavanyo lwegazi olungaphantsi kwama-500 / µL, olunxulunyaniswa nomkhuhlane ongaphezulu okanye olingana no-38ºC ngeyure enye. Le meko ixhaphake kakhulu kwizigulana ezinomhlaza emva kwekhemotherapy kwaye inokukhokelela kwiziphumo kunye neengxaki kunyango ukuba ayinyangwa kwangoko.

I-neutrophils zezona ziphambili zeeseli zegazi ezinoxanduva lokukhusela kunye nokulwa nosulelo, ixabiso eliqhelekileyo eliqwalaselwa phakathi kwe-1600 kunye ne-8000 / µL, enokwahluka ngokwelabhoratri. Xa inani le-neutrophils lilingana okanye likhulu kune-500 / µL, i-neutropenia eqatha iyaqwalaselwa, ukuze umntu abe semngciphekweni wokuhlaselwa zizifo ngamagciwane ahlala emzimbeni.

Oonobangela febrile neutropenia

IFebrile neutropenia yinto exhaphakileyo kwizigulana ezinomhlaza ezifumana ichemotherapy, yenye yezona zinto zibangela ukufa kwezi zigulana, kuba ukwehla kwee-neutrophils kwandisa umngcipheko wokuba nosulelo olubi.

Ukongeza kwi-chemotherapy, i-febrile neutropenia inokwenzeka njengesifo esinganyangekiyo esibangelwa ngumngundo, ibhaktiriya kunye neentsholongwane, ngakumbi intsholongwane ye-Epstein-Barr kunye ne-hepatitis. Funda ngezinye izizathu ze-neutropenia.

Unjani unyango

Unyango lwe-febrile neutropenia luyahluka ngokobunzima. Izigulana ezichongiweyo njenge-febrile neutropenia, apho inani le-neutrophils lingaphantsi okanye lilingana ne-200 / µL, zihlala ziphathwa ngokusetyenziswa kwee-antibiotics zodidi lwe-beta-lactams, i-cephalosporins yesine okanye i-carbapenems. Ukongeza, kwimeko yesigulana esingazinzanga eklinikhi okanye ekrokrelwa ukuba inentsholongwane enganyangekiyo, kunokucetyiswa ukusetyenziswa kwesinye isibulali zintsholongwane ukulwa nosulelo.

Kwiimeko zobungozi obuncinci be-febrile neutropenia, isigulana sihlala sibekwe iliso, kwaye kufuneka kwenziwe inani elipheleleyo lamagazi ngamaxesha athile ukujonga amanqanaba ee-neutrophils. Ukongeza, ukuba usulelo lokungunda okanye lwebhakteria luqinisekisiwe, ukusetyenziswa kwee-antimicrobials, nokuba zintsholongwane okanye ukubola, kunokucetyiswa ngugqirha kuxhomekeke kwiarhente ejongene nosulelo.

Xa i-febrile neutropenia yenzeka emva kwe-chemotherapy, kuyacetyiswa ukuba unyango lwe -antibiotic luqale ngokukhawuleza ngaphakathi kweyure enye emva kokujonga umkhuhlane.