Iifayile

Umxholo

• Phambi kokuba uthathe i-efavirenz,
• I-Efavirenz inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo okanye ezo zikhankanyiweyo KWICANDELO LOKUKHUSELEKILEYO, biza ugqirha ngoko nangoko:
• Iimpawu zokudlula ngaphezulu zinokubandakanya:

I-Efavirenz isetyenziswa kunye namanye amayeza ukunyanga intsholongwane kaGawulayo. I-Efavirenz ikudidi lwamayeza abizwa ngokuba zii-non-nucleoside reverse transcriptase inhibitors (NNRTIs). Isebenza ngokunciphisa inani le-HIV egazini. Nangona i-efavirenz ingayinyangi i-HIV, inokuwanciphisa amathuba akho okuba ne-immunodeficiency syndrome (i-AIDS) kunye nezifo ezinxulumene ne-HIV ezinje ngezifo ezomeleleyo okanye umhlaza. Ukuthatha la mayeza kunye nokwabelana ngesondo okukhuselekileyo nokwenza olunye utshintsho kwindlela yokuphila kunokunciphisa umngcipheko wokuhambisa (ukusasaza) intsholongwane kagawulayo kwabanye abantu.

I-Efavirenz iza njengepilisi njengepilisi emelwe ukuselwa ngomlomo. Ihlala ithathwa kanye ngemini ngamanzi amaninzi kwisisu esingenanto (ubuncinci iyure enye ngaphambi okanye iiyure ezi-2 emva kwesidlo). Thatha i-efavirenz ngexesha elifanayo yonke imihla. Ukuthatha i-efavirenz ngexesha lokulala kunokwenza ukuba iziphumo ebezingalindelekanga ezithile zingakhathazi. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-efavirenz kanye njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya iipilisi kunye neepilisi njengepilisi epheleleyo; ungahluleli, ungahlaleli, okanye uzityumze.

Ukuba awukwazi ukuginya yonke iyeza, usengathatha i-efavirenz ngokuxuba imixholo yephilisi nokutya okuthambileyo nokutya. Ukulungiselela idosi nganye, vula i-capsule kwaye ufefe imixholo kwi-1-2 yeetispuni zokutya okuthambileyo kwisitya esincinci. Ungasebenzisa ukutya okuthambileyo njengeapilesauce, ijeli yamagilebhisi, okanye iyogathi. Ngelixa ufefa, lumka ukuba ungachithi imixholo yecapsule, okanye uyisasaze emoyeni. Hlanganisa iyeza kunye nokutya okuthambileyo. Umxube kufuneka ujongeke ubumdaka kodwa akufuneki ubenamaqhuma. Kuya kufuneka ulitye iyeza kunye nomxube wokutya okuthambileyo ngaphakathi kwemizuzu engama-30 yokuxubeka. Xa ugqibile, yongeza enye iitispuni ezi-2 zokutya okuthambileyo kwisitya esingenanto, uvuse, kwaye utye ukuze uqiniseke ukuba ulifumene idosi epheleleyo yamayeza. Sukutya iiyure ezimbini ezilandelayo.

Ukuba i-efavirenz inikwa usana olungakwaziyo ukutya ukutya okuqinileyo, imixholo yephilisi inokuxutywa neetispuni ezi-2 zobushushu begumbi kwifomula encinci. Ngelixa ukhupha i-capsule, lumka ukuba ungachithi imixholo, okanye uyisasaze emoyeni. Umxube kufuneka ujongeke ubumdaka kodwa akufuneki ubenamaqhuma. Umxube kufuneka ufakwe kwisirinji emntwaneni kwisithuba semizuzu engama-30 exubekile. Xa ugqibile, yongeza iitispuni ezimbini ezongezelelweyo zefomula yosana kwisitya esingenanto, uvuse, kunye nesirinji ukondla umntwana ukuze uqiniseke ukuba ulinike idosi epheleleyo yamayeza. Musa ukunika amayeza umntwana ebhotileni. Musa ukutyisa umntwana kwiiyure ezi-2 ezizayo.

I-Efavirenz ilawula usulelo lwe-HIV, kodwa ayilunyangi. Qhubeka nokusela i-efavirenz nokuba uziva uphilile. Sukuyeka ukuthatha i-efavirenz ungakhange uthethe nogqirha wakho. Xa ubonelelo lwakho lwe-efavirenz luqala ukwehla, fumana okungakumbi kugqirha wakho okanye kwikhemesti. Ukuba uyaphoswa ngamayeza okanye uyeke ukuthatha i-efavirenz, imeko yakho kunokuba nzima ukunyanga.

I-Efavirenz ikwasetyenziswa namanye amayeza ukunceda ukuthintela usulelo kubasebenzi bokhathalelo lwempilo okanye abanye abantu abachanabeke i-HIV ngengozi. Thetha nogqirha wakho malunga neengozi zokusebenzisa la mayeza kwimeko yakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Phambi kokuba uthathe i-efavirenz,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-efavirenz nawaphi na amanye amayeza, okanye ukuba ngaba awudibani nezinye izithako ezikwiikhapilisi okanye iipilisi ze-efavirenz Buza ugqirha wakho okanye usokhemesti uluhlu lwezithako.
• Kuya kufuneka uyazi ukuba i-efavirenz ikwafumaneka ngokudibanisa nelinye iyeza elinegama le-Atripla. Xelela ugqirha wakho ukuba uthatha la mayeza ukuze uqiniseke ukuba awufumani mayeza afanayo kabini.
• xelela ugqirha wakho ukuba uthatha i-elbasvir kunye negrazoprevir (Zepatier). Ugqirha wakho usenokukuxelela ukuba ungathathi i-efavirenz ukuba uthatha eli yeza.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo nolungabhaliswanga, iivithamini, kunye nezongezelelo zesondlo ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya oku kulandelayo: i-antidepressants, artemether kunye ne-lumefantrine (Coartem), atazanavir (Reyataz), atorvastatin (Lipitor, eCaduet), atovaquone kunye ne-proguanil, bupropion (Wellbutrin, Zyban, abanye, kwi-Contrave), carbamazepine , Epitol, Equetro, Tegretol, Teril), clarithromycin (Biaxin, in Prevpac), cyclosporine (Gengraf, Neoral, Sandimmune), delavirdine (Rescriptor), diltiazem (iCardizem CD, iCartia XT, iDiltzac, iTaztia XT), i-ethinyl estradi (Estarylla, Ortho-Tri-Cyclen, Sprintec, abanye), etravirine (Intelence), etonogestrel (Implanon, Nexplanon, Nuvaring), felodipine, fosamprenavir (Lexiva), itraconazole (Sporanox), indinavir (Crixivan), levonorgest B inyathelo elinye, uSkyla, eClimera Pro, Seasonale, abanye), lopinavir (eKaletra), maraviroc (Selzentry), amayeza oxinzelelo, amayeza okugula ngengqondo, amayeza okuxhuzula, imethadone (iDolophine, iMethadose), nevirapine (Viramune) , Inicardipine (Cardene), i-nifedipine (A dalat, Afeditab, Procardia XL), norelgestromin (eXulane), phenobarbital, phenytoin (Dilantin, Phenytek), posaconazole (Noxafil), pravastatin (Pravachol), rifabutin (Mycobutin), rifampin (Rifadin, Rifadin, rilpivirine (Edurant, eComplera, Odefsey), ritonavir (Norvir, e Kaletra, Technivie, Viekira), saquinavir (Invirase), sedatives, sertraline (Zoloft), simeprevir (Olysio), simvastatin (Zocor, eVytorin), sirolim ), Iipilisi zokulala, i-tacrolimus (i-Envarsus XR, i-Prograf), i-tranquilizers, i-verapamil (Calan, Covera, Verelan, eTarka), voriconazole (Vfend), kunye ne-warfarin (Coumadin, Jantoven). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-efavirenz, okanye anganyusa umngcipheko wokuba ube nokubetha kwentliziyo okungaqhelekanga, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owasebenzisayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
• xelela ugqirha wakho ukuba ukhe wanethuba elide le-QT (ingxaki yentliziyo enqabileyo enokubangela ukuba utyhafe okanye ukubetha kwentliziyo ngendlela engaqhelekanga), ukubetha kwentliziyo ngokungaqhelekanga, ezinye iingxaki zentliziyo, ukhe wasela izixa ezikhulu zotywala, wasebenzisa iziyobisi ezitalatweni, okanye wasebenzisa kakhulu amayeza kagqirha. Xelela ugqirha wakho ukuba ukhe wanaso okanye wakha wanokudakumba okanye esinye isifo sengqondo, ukuxhuzula, ihepatitis (usulelo lwentsholongwane esibindini) okanye nasiphi na isifo sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Akufanele ukhulelwe ngexesha lonyango kunye nakwiiveki ezili-12 emva kwedosi yakho yokugqibela. Ukuba unokukhulelwa, kuya kufuneka ukuba ube novavanyo lokukhulelwa olubi ngaphambi kokuba uqale ukuthatha eli yeza kwaye usebenzise ulawulo lokuzalwa olusebenzayo ngexesha lonyango lwakho. I-Efavirenz inokunciphisa ukusebenza kweendlela zokucwangcisa zehomoni (iipilisi zolawulo lokuzalwa, iipatches, iiringi, izinto zokufakelwa, okanye inaliti), ngenxa yoko akufuneki uzisebenzise njengokuphela kwendlela yolawulo lokuzalwa ngexesha lonyango lwakho. Kuya kufuneka usebenzise indlela yesithintelo yolawulo lokuzalwa (isixhobo esivimba isidoda ukuba singene esibelekweni esifana nekhondom okanye uvalo) kunye nayiphi na enye indlela yolawulo lokuzalwa oyikhethileyo. Buza ugqirha wakho ukuba akuncede ukhethe indlela yolawulo lokuzalwa eya kukusebenzela. Ukuba uyakhulelwa ngelixa uthatha i-efavirenz, tsalela ugqirha wakho.
• akufuneki uncancise ibele ukuba wosulelwe yi-HIV okanye uthatha i-efavirenz.
• Kufuneka uyazi ukuba i-efavirenz inokukwenza wozele, ube nesiyezi, okanye ungakwazi ukugxila. Musa ukuqhuba imoto okanye usebenzise oomatshini de ube uyazi indlela elikuchaphazela ngayo eli yeza.
• buza ugqirha wakho malunga nokusetyenziswa okukhuselekileyo kweziselo ezinxilisayo ngelixa uthatha i-efavirenz. Utywala bunokwenza mandundu iziphumo ebezingalindelekanga ezivela kwi-efavirenz.
• Kuya kufuneka uyazi ukuba ngelixa uthatha amayeza ukunyanga usulelo lwe-HIV, amajoni akho omzimba angomelela kwaye aqale ukulwa nezinye izifo ezazisele zisemzimbeni wakho okanye zibangele ezinye iimeko zenzeke. Oku kunokubangela ukuba ukhule iimpawu zolo sulelo okanye iimeko. Ukuba uneempawu ezintsha okanye eziba mandundu ngexesha lonyango lwakho nge-efavirenz, qiniseka ukuxelela ugqirha wakho.
• Kuya kufuneka uyazi ukuba amanqatha omzimba wakho anganyuka okanye afudukele kwiindawo ezahlukeneyo zomzimba wakho njengamabele akho kunye nomqolo wangasentla, intamo (’’ inyathi ’), nakwisijikelezileyo sesisu sakho. Ungabona ukulahleka kwamafutha omzimba ebusweni bakho, kwimilenze nakwiingalo.
• Kufuneka uyazi ukuba i-efavirenz inokubangela utshintsho kwiingcinga zakho, kwindlela oziphatha ngayo, okanye empilweni yakho. Fowunela ugqirha wakho ngoko nangoko xa uvela kwezi mpawu zilandelayo ngelixa uthatha i-efavirenz: ukudakumba, ukucinga ngokuzibulala okanye ukucwangcisa okanye ukuzama ukwenza njalo, ukuba nomsindo okanye ukuba ndlongondlongo, ukubona izinto ezingekhoyo (ukubona izinto okanye ukuva amazwi angabikho) ukulahleka kwebala kunye nenyani, okanye ezinye iingcinga ezingaqhelekanga. Qiniseka ukuba usapho lwakho luyazazi ukuba zeziphi iimpawu ezinokubanzima ukuze bakwazi ukubiza ugqirha wakho ukuba awukwazi ukuzifunela unyango ngokwakho.
• Kuya kufuneka uyazi ukuba i-efavirenz inokubangela iingxaki zesistim ezinobunzima, kubandakanya i-encephalopathy (isifo esibi nesinokubulala ingqondo) iinyanga okanye iminyaka emva kokuba uthathe i-efavirenz. Nangona iingxaki zemithambo-luvo zinokuqala emva kokuba uthathe i-efavirenz kangangexesha elithile, kubalulekile kuwe nogqirha wakho ukuba niqonde ukuba zingabangelwa yi-efavirenz. Fowunela ugqirha ngoko nangoko xa unengxaki yokulingana okanye yokulungelelanisa, ukudideka, iingxaki zememori, kunye nobunye ubunzima obubangelwa kukungasebenzi kakuhle kwengqondo, nangaliphi na ixesha kunyango lwakho nge-efavirenz. Ugqirha wakho angakuxelela ukuba uyeke ukuthatha i-efavirenz.

Thetha nogqirha wakho malunga nokutya igrapefruit kunye nokusela ijusi yamagilebhisi ngelixa uthatha eli yeza.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Efavirenz inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• isisu esibuhlungu
• urhudo
• ukuqunjelwa
• intloko ebuhlungu
• ukudideka
• ukulibala
• Ukuziva uxhalabile, usoyika okanye uphazamisekile
• imeko eyonwabileyo ngokungaqhelekanga
• ubunzima bokulala okanye ukulala
• amaphupha angaqhelekanga
• intlungu

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo okanye ezo zikhankanyiweyo KWICANDELO LOKUKHUSELEKILEYO, biza ugqirha ngoko nangoko:

• ifiva
• irhashalala
• ukurhawuzelela
• ukuxobuka, ukudubula, okanye ukuchitha ulusu
• izilonda zomlomo
• iliso elipinki
• ukudumba kobuso bakho
• isiqaqa
• ukubetha kwentliziyo ngokungaqhelekanga
• ukudinwa kakhulu
• ukunqongophala kwamandla
• Ukuphelelwa ngumdla wokutya
• iintlungu kwinxalenye ephezulu yesisu
• ukopha okungaqhelekanga okanye ukugruzuka
• mthubi ulusu okanye amehlo
• Iimpawu ezinjengomkhuhlane
• ukuxhuzula

I-Efavirenz inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni.Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

• iintshukumo zomzimba wakho ongenakuzilawula
• isiyezi
• intloko ebuhlungu
• ubunzima bokugxila
• uvalo
• ukudideka
• ukulibala
• ubunzima bokulala okanye ukulala
• amaphupha angaqhelekanga
• ukozela
• ukubona izinto ezingekhoyo (ukubona izinto okanye ukuva amazwi angabikho)
• imeko eyonwabileyo ngokungaqhelekanga
• iingcinga ezingaqhelekanga

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho angayalela iimvavanyo ezithile zelebhu ukujonga impendulo yomzimba wakho kwi-efavirenz.

Phambi kokuba wenze uvavanyo lwaselebhu, xelela ugqirha wakho kunye nabasebenzi baselebhu ukuba uthatha i-efavirenz.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Sustiva^®

• Atripla^® (iqulethe i-Efavirenz, i-Emtricitabine, i-Tenofovir)