I-Tranexamic acid: yintoni, yintoni eyenzelweyo kunye nendlela yokusebenzisa

Umxholo

• Yenzelwe ntoni
• Kusetyenziswa kwanjani
• Iziphumo ebezingalindelekanga ezinokwenzeka
• Ngubani ongafanele asebenzise

I-Tranexamic acid yinto ethintela isenzo se-enzyme eyaziwa ngokuba yi-plasminogen, edla ngokubopha amahlwili ukuyitshabalalisa kunye nokubathintela ekwenzeni i-thrombosis, umzekelo. Nangona kunjalo, kubantu abanezifo ezenza igazi licekeceke kakhulu, iplasminogen inokuthintela amahlwili ekubumbeni ngexesha lokusikwa, umzekelo, okwenza kube nzima ukunqanda ukopha.

Ukongeza, le nto ikwathintela ukuveliswa kwesiqhelo se-melanin kwaye, ke, inokusetyenziselwa ukukhanyisa amabala athile esikhumba, ngakumbi kwimeko ye-melasma.

Ngenxa yokusebenza kwayo kabini, le nto inokufunyanwa ngohlobo lweepilisi, ukunqanda ukopha, okanye ngohlobo lwekhrim, ukunceda ukukhanyisa amabala. Ingasetyenziselwa njengeliza esibhedlele, ukulungisa imeko ezingxamisekileyo ezinxulumene nokopha kakhulu.

Yenzelwe ntoni

Le nto iboniswe ukulungiselela:

• Ukunciphisa umngcipheko wokopha ngexesha lotyando;
• Khanyisa imelasmas kunye namabala amnyama kulusu;
• Phatha ukopha okunxulunyaniswa ne-fibrinolysis egqithisileyo.

Ukusetyenziswa kwale nto ngohlobo lweepilisi ukunyanga okanye ukunqanda ukubonakala kokopha kufuneka kwenziwe kuphela emva kwengcebiso kagqirha.

Kusetyenziswa kwanjani

Idosi kunye nexesha lokusetyenziswa kweli yeza kufuneka lihlale likhokelwa ngugqirha, nangona kunjalo izikhombisi ngokubanzi zezi:

• Phatha okanye uthintele ukopha ebantwaneni: thabatha i-10 ukuya kuma-25 mg / kg, kabini ukuya kathathu ngemini;
• Phatha okanye uthintele ukopha kubantu abadala1 ukuya kwi-1.5 yeegram, amaxesha amabini ukuya kwamane ngosuku, malunga neentsuku ezi-3. Okanye i-15 ukuya kuma-25 mg / ngosuku ukuba unyango luhlala ngaphezulu kweentsuku ezi-3;
• Khanyisa amabala esikhumbaSebenzisa ikhrimu enoxinzelelo phakathi kwe-0.4% kunye ne-4% kwaye uyisebenzise ukukhanyisa. Thambisa into yokuzigcina elangeni emini.

Idosi yeepilisi inokwanela, ngugqirha, ngokwembali yesigulana, ukusetyenziswa kwamanye amayeza kunye neziphumo ezibonisiweyo.

Iziphumo ebezingalindelekanga ezinokwenzeka

Iziphumo ebezingalindelekanga zixhaphakileyo zibandakanya isicaphucaphu, ukugabha, urhudo kunye nokwehla okuphawulekayo koxinzelelo lwegazi.

Ngubani ongafanele asebenzise

I-Tranexamic acid akufuneki isetyenziswe kubantu abane-hemophilia abafumana unyango ngelinye ichiza, kwizigulana ezine-intravascular coagulation okanye kubukho begazi kumchamo. Ukongeza, kufanele ukuba kuthintelwe ukwenza i-thoracic okanye isisu, kuba kukho umngcipheko omkhulu wokugruzuka.