Ngaba kukhuselekile kwaye kusemthethweni ukusebenzisa i-Apetamin Isiraphu yokufumana ubunzima?

Umxholo

• Yintoni iApetamin?
• Ingaba isebenza kanjani?
• Ngaba iyasebenza ekuzuzeni ubunzima?
• Ngaba i-Apetamin isemthethweni?
• Iziphumo ebezingalindelekanga ezinokubakho ze-Apetamin
• Umgca wezantsi

Kwabanye abantu, ukufumana ubunzima kunokuba nzima.

Ngaphandle kokuzama ukutya iikhalori ezininzi, ukunqongophala kokutya kuyabathintela ekufezekiseni iinjongo zabo.

Abanye babhenela ekufumaneni ubunzima, njengeapetamin. Sisiraphu sevithamini esithandwayo ngokufuthi ekufunwayo ukuba sikuncede utyebe ngokwandisa umdla wakho wokutya.

Nangona kunjalo, ayifumaneki kwiivenkile zezempilo okanye kwiiwebhusayithi ezaziwayo eMelika, okwenza kube nzima ukuthenga. Oku kunokukwenza uzibuze ukuba kukhuselekile kwaye kusemthethweni.

Eli nqaku liphonononge i-Apetamin, kubandakanya ukusetyenziswa kwayo, ukuba semthethweni kwayo kunye neziphumo ebezingalindelekanga.

Yintoni iApetamin?

I-Apetamin sisiraphu sevithamini esithengiswa njengesongezo sokufumana ubunzima. Yaphuhliswa yi-TIL Healthcare PVT, inkampani evelisa amayeza eseIndiya.

Ngokweelebhile zokuvelisa, itispuni e-1 (5 ml) yesiraphu ye-Apetamin iqulethe:

• ICyproheptadine hydrochloride: 2 mg
• I-lysine hydrochloride: 150 mg
• IPyridoxine (ivithamini B6) ihydrochloride: 1 mg
• I-thiamine (i-vitamin B1) i-hydrochloride: 2 mg
• INicotinamide (ivithamini B3): 15 mg
• I-Dexpanthenol (enye indlela ye-vitamin B5): 4.5 mg

Indibaniselwano ye-lysine, iivithamini, kunye ne-cyproheptadine zibanga ukunceda ukuzuza ubunzima, nangona kuphela eyokugqibela ibonakalisiwe ukuba inokwandisa umdla wokutya njengempembelelo yecala (,).

Nangona kunjalo, i-cyproheptadine hydrochloride isetyenziswa ikakhulu njenge-antihistamine, uhlobo lweziyobisi ezenza lula ukungabikho komzimba njengempumlo ebabayo, ukurhawuzelela, imihlathi kunye namehlo anamanzi ngokuvimba i-histamine, into eyenziwa ngumzimba wakho xa inempendulo (3).

I-Apetamin ifumaneka kwisiraphu kunye nefom yeethebhulethi. Isiraphu ngokubanzi iqulethe iivithamini kunye ne-lysine, ngelixa iipilisi zibandakanya kuphela i-cyproheptadine hydrochloride.

Isongezelelo asivunywanga luLawulo lwezoKutya kunye noLawulo lweziyobisi (i-FDA) ngenxa yokhuseleko nokusebenza kokukhathazeka, kwaye akukho semthethweni ukuyithengisa e-United States nakwamanye amazwe amaninzi (4).

Nangona kunjalo, ezinye iiwebhusayithi ezincinci ziyaqhubeka nokuthengisa i-Apetamin ngokungekho mthethweni.

I-Apetamin ithengiswa njengesongezelelo esikunceda ukuba ufumane ubunzima ngokwandisa umdla wokutya.

Ingaba isebenza kanjani?

I-Apetamin inokukhuthaza ukutyeba ngenxa yokuba iqulethe i-cyproheptadine hydrochloride, i-antihistamine enamandla eneziphumo ebezingalindelekanga ezibandakanya ukwanda kokutya.

Nangona kungacacanga ukuba le nto iyonyusa njani umdla wokutya, iithiyori ezininzi zikhona.

Okokuqala, i-cyproheptadine hydrochloride ibonakala ikwandisa amanqanaba okukhula kwe-insulin (IGF-1) kubantwana abaphantsi komzimba. IGF-1 luhlobo lwehomoni enxulunyaniswe nokuzuza ubunzima ().

Ukongeza, kubonakala ngathi iyasebenza kwi-hypothalamus, icandelo elincinci lengqondo yakho elilawula ukutya, ukutya ukutya, iihomoni, kunye neminye imisebenzi emininzi yebhayoloji ().

Okwangoku, kufuneka uphando olongezelelekileyo lokuqonda indlela i-cyproheptadine hydrochloride enokunyusa ngayo umdla wokutya kunye nokukhokelela ekuzuzeni ubunzima.

Ukongeza, isiraphu ye-Apetamin iqulethe i-amino acid l-lysine, edityaniswe nokwanda kokutya kwizifundo zezilwanyana. Nangona kunjalo, izifundo zabantu ziyafuneka ().

Ngaba iyasebenza ekuzuzeni ubunzima?

Nangona uphando nge-Apetamin kunye nokuzuza ubunzima kusilela, izifundo ezininzi zifumanise ukuba i-cyproheptadine hydrochloride, eyona nto iphambili kuyo, inokunceda ukutyeba kubantu abaphulukene nomdla wokutya kwaye basemngciphekweni wokungondleki.

Ukongeza, isifundo seveki ezili-12 kubantwana abali-16 nakwishumi elivisayo abane-cystic fibrosis (isifo esingofuzo esinokubonisa ukuphulukana nesidlo) kuqatshelwe ukuba ukuthatha i-cyproheptadine hydrochloride mihla le kukhokelele ekwandeni kobunzima, xa kuthelekiswa ne-placebo ().

Uphengululo lwezifundo ezingama-46 kubantu abaneemeko ezahlukeneyo zaqaphela ukuba into yayinyamezeleka kwaye inceda abantu abaphantsi kwesisindo ukuba batyebe. Nangona kunjalo, khange ibancede abantu abanezifo eziqhubela phambili, ezinje nge-HIV kunye nomhlaza ().

Ngelixa i-cyproheptadine inokunceda abo basemngciphekweni wokungondleki, inokukhokelela ekuzuzeni ubunzima obugqithisileyo kubantu abatyebe kakhulu okanye abo banobunzima obusempilweni.

Umzekelo, uphononongo kubantu abangama-499 abavela kwiDemocratic Republic of Congo baveze ukuba i-73% yabathathi-nxaxheba bayisebenzisa gwenxa i-cyproheptadine kwaye basemngciphekweni wokutyeba kakhulu).

Ngamafutshane, ngelixa i-cyproheptadine hydrochloride inokunceda abantu abaphantsi kwesisindo ukuba batyebe, inokubeka umntu ophakathi emngciphekweni wokutyeba, eyingxaki ebalulekileyo kwihlabathi liphela.

I-Apetamin iqulethe i-cyproheptadine hydrochloride, enokuthi inyuse umdla wokutya njengempembelelo esecaleni. Kwithiyori, inokwenza njalo ngokunyusa amanqanaba e-IGF-1 kunye nokusebenza kwindawo yengqondo elawula ukutya kunye nokutya.

Ngaba i-Apetamin isemthethweni?

Ukuthengisa i-Apetamin akukho semthethweni kumazwe amaninzi, kubandakanya naseMelika.

Kungenxa yokuba iqulethe i-cyproheptadine hydrochloride, i-antihistamine efumaneka kuphela nge-amayeza e-United States ngenxa yenkxalabo yezokhuseleko. Ukuyisebenzisa gwenxa le nto kunokubangela iziphumo ezibi, ezinje ngokusilela kwesibindi kunye nokufa (, 10).

Ukongeza, i-Apetamin ayivunywanga okanye ilawulwa yi-FDA, oko kuthetha ukuba iimveliso ze-Apetamin zinokungabinayo into ebhalwe kwileyibhile (,).

I-FDA ikhuphe izaziso zokuthimba kunye nezilumkiso zokungenisa i-Apetamin kunye nezinye iisiraphu zevithamini eziqukethe i-cyproheptadine ngenxa yokhuseleko kunye nokusebenza ngokukuko (4).

Ukuthengiswa kwe-Apetamin kuthintelwe kumazwe amaninzi, kubandakanya i-United States, kuba iqulethe i-cyproheptadine hydrochloride, iyeza lonyango kuphela.

Iziphumo ebezingalindelekanga ezinokubakho ze-Apetamin

Iapetamin inezinto ezininzi ezichaphazela ukhuseleko kwaye ayikho semthethweni kumazwe amaninzi, yiyo loo nto iivenkile ezaziwayo eUnited States zingazithengisi.

Okwangoku, abantu bayakwazi ukufumana i-Apetamin engeniswa ngokungekho mthethweni kwiiwebhusayithi ezincinci, uluhlu olucwangcisiweyo, kunye namajelo eendaba ezentlalo.

Inkxalabo enkulu kukuba iqulethe i-cyproheptadine hydrochloride, iyeza lonyango kuphela elinxulunyaniswe neziphumo ebezingalindelekanga ezahlukeneyo, kubandakanya ():

• ukozela
• isiyezi
• ukungcangcazela
• ukucaphuka
• ukungaboni kakuhle
• isicaphucaphu kunye norhudo
• ityhefu yesibindi kunye nokusilela

Ukongeza, inokusebenzisana notywala, ijusi yeziqhamo, kunye nezinye iziyobisi, kubandakanya neyeza lokudandatheka, amayeza esi sifo sikaParkinson, kunye nezinye ii-antihistamines (3).

Ngenxa yokuba i-Apetamin ingeniswa ngokungekho mthethweni e-United States, ayilawulwa yi-FDA. Ke, inokuqulatha iintlobo ezahlukeneyo okanye izixa zezithako kunokuba zidwelisiwe kwileyibhile ().

Ukujonga imeko yayo engekho mthethweni eMelika nakwamanye amazwe, kunye neziphumo ezibi, kuya kufuneka uphephe ukuzama oku kongezwa.

Endaweni yoko, thetha nomboneleli wakho wezempilo ukumisela olona nyango lusebenzayo nolona lusebenzayo ukuba unengxaki yokufumana ubunzima okanye imeko yonyango enciphisa ukutya kwakho.

Iapetamin ayikho mthethweni eUnited States nakwamanye amazwe amaninzi. Kwaye, eyona nto iphambili kuyo, i-cyproheptadine hydrochloride, inxulunyaniswe neziphumo ebezingalindelekanga ezibi kwaye ifumaneka kuphela ngugqirha.

Umgca wezantsi

I-Apetamin sisiraphu yevithamini ebanga ukuba inceda ukuzuza ubunzima.

Iqulethe i-cyproheptadine hydrochloride, iyeza kuphela elinokuyalela ukutya.

Akukho mthethweni ukuthengisa iApetamin eMelika nakwezinye iindawo. Kwaye i-FDA ayiyilawuli kwaye ikhuphe izaziso zokuthimba kunye nezilumkiso zokungenisa.

Ukuba ujonge ukutyeba, thetha nomntu otya ukutya kunye nomnikezeli wakho wezempilo ukuze enze isicwangciso esikhuselekileyo nesisebenza ngokuhambelana neemfuno zakho, kunokuba uthembele kwizongezo ezingekho semthethweni.