INetupitant kunye nePalonosetron

Umxholo

• Ngaphambi kokuba uthathe i-netupitant kunye ne-palonosetron,
• I-Netupitant kunye ne-palonosetron zinokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko okanye ufune unyango olungxamisekileyo:

Indibaniselwano ye-netupitant kunye ne-palonosetron isetyenziselwa ukuthintela isicaphucaphu kunye nokugabha okubangelwa ngumhlaza wekhemotherapy. I-Netupitant ikudidi lwamayeza abizwa ngokuba zii-neurokinin (NK1) antagonists. Isebenza ngokuthintela i-neurokinin, into yendalo kwingqondo ebangela isicaphucaphu nokugabha. I-Palonosetron ikwiklasi yamayeza abizwa ngokuba yi-5-HT₃ abachasi be-receptor. Isebenza ngokuthintela i-serotonin, into yendalo emzimbeni ebangela isicaphucaphu nokugabha.

Indibaniselwano ye-netupitant kunye ne-palonosetron iza njengecapsule yokuthatha ngomlomo. Ihlala ithathwa malunga neyure e-1 ngaphambi kokuqala kwe-chemotherapy kunye okanye ngaphandle kokutya. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-netupitant kunye ne-palonosetron kanye njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-netupitant kunye ne-palonosetron,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-netupitant kunye ne palonosetron, alosetron (Lotronex), dolasetron (Anzemet), granisetron (Sancuso), ondansetron (Zofran, Zuplenz), nawaphi na amanye amayeza, okanye naziphi na izithako . Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye neemveliso zamayeza owathathayo. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: benzodiazepines kubandakanya ialprazolam (Xanax), midazolam, kunye netriazolam (Halcion); amayeza athile e-chemotherapy anje ngecyclophosphamide (Cytoxan), i-docetaxel (Docefrez, Taxotere), etoposide, ifosfamide (Ifex), imatinib (Gleevec), irinotecan (Camptosar), paclitaxel (Taxol), vinblastine, vincristine, kunye ne-vinorebine dexamethasone; erythromycin (EES, Ery-tab, abanye); fentanyl (Abstral, Actiq, Duragesic, Fentora, Lazanda, Onsolis, Subsys); ketoconazole (Nizoral); lithium (Lithobid); amayeza ukunyanga i-migraines efana ne-almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), kunye zolmitriptan (Zomig); imethylene eluhlaza okwesibhakabhaka; i-mirtazapine (iRemeron); I-monoamine oxidase (MAO) inhibitors kubandakanya isocarboxazid (Marplan), linezolid (Zyvox), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), kunye ne-tranylcypromine (iParnate); phenobarbital; irifampin (Rifadin, Rimactane, eRifater, eRifamate); i-serotonin reuptake inhibitors (i-SSRIs) ekhethiweyo njenge-citalopram (i-Celexa), i-escitalopram (i-Lexapro), i-fluoxetine (i-Prozac, i-Sarafem, kwi-Symbyax), i-fluvoxamine (i-Luvox), i-paroxetine (i-Brisdelle, i-Paxil, i-Pexeva) kunye ne-sertraline (i-Zoloft); kunye ne-tramadol (Conzip, Ultram, kwi-Ultracet). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe unesifo sesibindi okanye sezintso.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwe ngelixa uthatha i-netupitant kunye ne-palonosetron, tsalela ugqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

I-Netupitant kunye ne-palonosetron kufuneka zithathwe kuphela ngaphambi kwe-chemotherapy njengoko kuyalelwe ngugqirha wakho. Akufuneki ukuba ithathwe rhoqo ngokucwangcisiweyo.

I-Netupitant kunye ne-palonosetron zinokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• intloko ebuhlungu
• isisu esibuhlungu
• isilungulela
• ukuqhina
• ubuthathaka
• ukuba bomvu kwesikhumba

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko okanye ufune unyango olungxamisekileyo:

• urhwebo
• irhashalala
• ukurhawuzelela
• ubunzima bokuphefumla okanye ukugwinya
• ukuqhawukelwa ngumphefumlo
• isiyezi, intloko ebuthathaka, nokufa isiqaqa
• ukukhawuleza, ukukhawuleza okanye ukungahambi kakuhle kwentliziyo
• ukuphazamiseka
• ukubona izinto ezingekhoyo (ukubona izinto okanye ukuva amazwi angabikho)
• ifiva
• ukugungxula
• ukubila okugqithisileyo
• ukudideka
• isicaphucaphu, ukugabha kunye norhudo
• ukulahleka koququzelelo
• izihlunu eziqinileyo okanye ezijijekileyo
• ukuxhuzula
• isiqaqa (ukulahleka kwengqondo)

I-Netupitant kunye ne palonosetron zinokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nokukhanya, ubushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Lahla naliphi na iyeza eliphelelwe lixesha okanye elingasafunekiyo. Thetha kumachiza wakho malunga nokulahla ngokufanelekileyo amayeza akho.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Gcina lonke ixesha lokudibana nogqirha wakho.

Musa ukuvumela nabani na ukuba athathe amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• I-Akynzeo^®