Buza iNgcali: Hlala phantsi neGastro

Umxholo

• Ngaba kunokwenzeka ukuba ungaxilongwa kakubi nge-ulcerative colitis (UC)? Ndiya kwazi njani ukuba sisifo esingalunganga okanye ukuba ndifuna unyango olwahlukileyo?
• Zeziphi iingxaki zokunganyangeki okanye ukungaphathwa kakuhle kwe-UC?
• Zeziphi iindlela zonyango ezikhoyo ze-UC? Ngaba zikhona ezisebenza bhetele kunabanye?
• Ulwaphulo-mthetho
• Amayeza okubulala iintsholongwane
• Abaxinzeleli bezixhobo
• Unyango lwebhayoloji
• Ngaba zikhona iziphumo ebezingalindelekanga zamayeza ekufuneka ndizazi?
• Iziyobisi ezichasayo
• Amayeza okubulala iintsholongwane
• Abaxinzeleli bezixhobo
• Unyango lwebhayoloji
• Ndizokwazi njani ukuba unyango lwam alusebenzi kakuhle?
• Zeziphi izinto eziqhelekileyo ezibangela i-UC?
• Iqheleke kangakanani i-UC? IBDs? Ngaba lilifa?
• Ngaba lukhona unyango lwendalo lwe-UC? Olunye unyango? Ngaba bayasebenza?
• Unyango lokutya
• Unyango ngamayeza esintu
• Ulawulo loxinzelelo
• Zilolonge
• Ngaba kufuneka ndiqwalasele utyando?
• Ungalufumana phi ulwazi oluthe kratya kwi-UC okanye ufumane inkxaso kubantu abaphila nale meko?

Ngaba kunokwenzeka ukuba ungaxilongwa kakubi nge-ulcerative colitis (UC)? Ndiya kwazi njani ukuba sisifo esingalunganga okanye ukuba ndifuna unyango olwahlukileyo?

Abantu bahlala bedida i-UC nesifo sikaCrohn. ICrohn's sisifo sesisu esivuthayo esiqhelekileyo (IBD). Ezimbalwa zeempawu ziyafana, njengokuxolelwa kunye nokuphazamiseka.

Ukufumanisa ukuba unayo i-UC okanye iCrohn's, ndwendwela ugqirha wakho kwaye kuvavanywe. Kuya kufuneka uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde ukuba uphinde upoze, Kuya kufuneka uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde ukuba uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde luf lus uve ng n n n kanye kanye kanye kanye kanye nezo, kusenokufuneka ukuba uphinde uphinde uphinde wenze i-colonoscopy, okanye ugqirha angayalela i-X-ray yamathumbu amancinci ukujonga ukuba ayichaphazelekanga na. Ukuba unayo, unokuba nesifo sikaCrohn. I-UC ichaphazela kuphela ikholoni. Ngokwahlukileyo, iiCrohn's zinokuchaphazela naliphi na icandelo lesisu sakho (GI).

Zeziphi iingxaki zokunganyangeki okanye ukungaphathwa kakuhle kwe-UC?

Ukunyangwa ngokungalunganga okanye ukunganyangwa kwe-UC kunokubangela iintlungu zesisu, isifo sohudo kunye nokuphuma kwegazi. Ukopha ngamandla kunokubangela ukudinwa okukhulu, uphawu lwe-anemia, kunye nokuphefumla okufutshane. Ukuba i-UC yakho ibukhali kangangokuba ayiphenduli kunyango, ugqirha unokucebisa ukuba kususwe ikholoni yakho (ekwabizwa ngokuba ngamathumbu amakhulu).

Zeziphi iindlela zonyango ezikhoyo ze-UC? Ngaba zikhona ezisebenza bhetele kunabanye?

Unokhetho olulandelayo lonyango lwe-UC:

Ulwaphulo-mthetho

La machiza ahlala eyindlela yokuqala yokunyanga i-UC. Babandakanya i-corticosteroids kunye ne-5-aminosalicylates (5-ASAs). Kuxhomekeke ekubeni leliphi na icandelo lekholoni elichaphazelekayo, ungawathatha ngomlomo la machiza, njenge-suppository, okanye njenge-enema.

Amayeza okubulala iintsholongwane

Oogqirha bamisela amayeza okubulala iintsholongwane ukuba barhanela ukuba kukho usuleleko kwikholoni yakho. Nangona kunjalo, abantu abane-UC bahlala becetyiswa ukuba bangathathi i-antibiotics kuba banokubangela urhudo.

Abaxinzeleli bezixhobo

La mayeza anokulawula ukudumba. Babandakanya i-mercaptopurine, azathioprine, kunye necyclosporine. Hlala uqhagamshelana nogqirha wakho ukuba uthatha ezi zinto. Iziphumo ebezingalindelekanga zinokuchaphazela isibindi sakho kunye nepancreas.

Unyango lwebhayoloji

Unyango lwe-Biologic lubandakanya i-Humira (adalimumab), i-Remicade (infliximab), kunye ne-Simponi (golimumab). Ziyaziwa ngokuba yi-tumor necrosis factor (TNF) inhibitors. Zilawula impendulo yakho yomzimba engaqhelekanga. I-Entyvio (vedolizumab) isetyenziselwa unyango lwe-UC kubantu abangaphenduliyo okanye abangakwaziyo ukunyamezela ezinye iindlela zonyango.

Ngaba zikhona iziphumo ebezingalindelekanga zamayeza ekufuneka ndizazi?

Oku kulandelayo luluhlu lwamachiza aqhelekileyo e-UC aneziphumo ebezingalindelekanga eziqhelekileyo:

Iziyobisi ezichasayo

Iziphumo eziqhelekileyo ezichaphazelekayo ze-5-ASA zibandakanya ukugabha, isicaphucaphu, kunye nelahleko lokutya.

Kwixesha elide, i-corticosteroids inokukhokelela kwiziphumo ebezingalindelekanga ezinje ngoxinzelelo oluphezulu lwegazi, ukonyuka komngcipheko wosulelo, amanqanaba eswekile yegazi, amabala, ukutyeba, ukutshintsha kwemeko, ikati, ukungalali, kunye namathambo.

Amayeza okubulala iintsholongwane

I-Cipro kunye neFlagyl zihlala zichazwe kubantu abane-UC. Iziphumo ebezingalindelekanga eziqhelekileyo zibandakanya isisu esibuhlungu, urhudo, ukuphelelwa ngumdla wokutya, kunye nokugabha.

I-Cipro yintsholongwane ye-fluoroquinolone. I-Fluoroquinolones inokuwunyusa umngcipheko weenyembezi ezinzulu okanye uqhekeko kwi-aorta, enokubangela ukopha okunobuzaza nokubulala.

Abantu abadala kunye nabantu abanembali ye-aneurysms okanye izifo ezithile zentliziyo banokuba semngciphekweni omkhulu. Esi siganeko sichaseneyo sinokwenzeka ngayo nayiphi na i-fluoroquinolone ethathwe ngomlomo okanye ngenaliti.

Abaxinzeleli bezixhobo

I-6-mercaptopurine (6-MP) kunye ne-azathioprine (AZA) inokubangela iziphumo ebezingalindelekanga njengokunciphisa ukunganyangeki kusulelo, umhlaza wolusu, ukudumba kwesibindi kunye ne-lymphoma.

Unyango lwebhayoloji

Unyango lwe-Biologic lubandakanya i-Humira (adalimumab), i-Remicade (infliximab), i-Entyvio (vedolizumab), i-Certolizumab (i-Cimzia), kunye ne-Simponi (i-golimumab).

Iziphumo eziqhelekileyo ezichaphazelekayo zibandakanya ukurhawuzelela, ukuba bomvu, iintlungu okanye ukudumba kancinci kufutshane nendawo yenaliti, umkhuhlane, intloko ebuhlungu, ukugodola kunye nerhashalala.

Ndizokwazi njani ukuba unyango lwam alusebenzi kakuhle?

Ukuba iyeza lakho alisebenzi, uya kuba nohudo oluqhubekayo, ukuphuma kwegazi, kunye nentlungu esiswini-nasemva kweeveki ezintathu ukuya kwezine zokuba useleza.

Zeziphi izinto eziqhelekileyo ezibangela i-UC?

Iziphumo eziqhelekileyo ze-UC zibandakanya ubisi, iimbotyi, ikofu, iimbewu, i-broccoli, umbona kunye notywala.

Iqheleke kangakanani i-UC? IBDs? Ngaba lilifa?

Ngokutsho koqikelelo lwangoku, malunga nokuhlala ne-IBD. Ukuba unelungu losapho eline-IBD, linokunyusa umngcipheko wokuphuhlisa elinye.

• Ukuxhaphaka kwe-UC ngama-238 kubo bonke abantu abadala abayi-100,000.
• Ukuxhaphaka kweCrohn's kumalunga nama-201 kubantu abadala abangama-100,000.

Ngaba lukhona unyango lwendalo lwe-UC? Olunye unyango? Ngaba bayasebenza?

Kubantu abangenako ukunyamezela amayeza, kukho ezinye iindlela ezimbalwa.

Unyango lokutya

Ukutya okusezantsi kwifayibha kunye namanqatha kubonakala kuluncedo ekunciphiseni ubungakanani be-UC flare-ups. Ukuphelisa ukutya okuthile kwindlela otya ngayo kunokuba nefuthe elifanayo. Umzekelo, ubisi, utywala, inyama, kunye nokutya okuphezulu.

Unyango ngamayeza esintu

Amayeza e-herbal angahluka kunyango lwe-UC. Babandakanya iBoswellia, imbewu ye-psyllium / ikhoba, kunye ne-turmeric.

Ulawulo loxinzelelo

Unokukuthintela ukubuyela umva kwe-UC ngonyango lokunciphisa uxinzelelo, njengeyoga okanye ukucamngca.

Zilolonge

Ukongeza imisebenzi yomzimba yesiqhelo yesiqhelo kunokunceda ukulawula i-UC yakho.

Ngaba kufuneka ndiqwalasele utyando?

Phantse ama-25 ukuya kuma-40 ekhulwini abantu abane-UC bafuna ukuhlinzwa ukuze basuse ikholoni.

Ugqirha luyimfuneko ngenxa yoku kulandelayo:

• ukusilela kunyango
• ukopha kakhulu
• iziphumo ebezingalindelekanga ezibi zamayeza athile

Ungalufumana phi ulwazi oluthe kratya kwi-UC okanye ufumane inkxaso kubantu abaphila nale meko?

Ubuncwane obunqabileyo nobungqina obusekelwe kubungqina yiCrohn's kunye neColitis Foundation yaseMelika. Yintlangano engenzi nzuzo eneetoni zolwazi oluncedo kulawulo lwe-UC.

Unokufumana ulwazi ngakumbi ngokujoyina iindawo ezahlukeneyo zosasazo zase-UC. Uya kuzuza ngokudibana nokunxibelelana nabanye abantu abajongana nemicimbi efanayo.

Unokunceda ukuxhasa ngokulungiselela iintlanganiso, iminyhadala, kunye nemisebenzi. Oku kunika ithuba kubantu abachaphazeleka sesi sifo ukutshintshiselana ngeengcebiso, amabali kunye nezixhobo.

Ugqirha Saurabh Sethi ngugqirha oqinisekisiweyo webhodi ojolise kwi-gastroenterology, hepatology, kunye ne-endoscopy ephambili yokungenelela. Kwi-2014, uGqirha Sethi wagqibezela i-gastroenterology kunye ne-hepatology ubudlelwane e-Beth Israel Deaconess Medical Centre kwiSikolo sezoNyango i-Harvard. Kungekudala emva koko, wagqiba ubudlelwane bakhe be-endoscopy eqhubele phambili kwiYunivesithi yaseStanford e2015. UGqirha Sethi ubebandakanyeka kwiincwadi ezininzi kunye nakupapasho kuphando, kubandakanya ngaphezulu kwe-30 yokuphononongwa ngoontanga. Umdla kaGqirha Sethi ubandakanya ukufunda, ukubhloga, ukuhamba, kunye nokukhuthaza impilo yoluntu.