Yintoni i-calcitonin kwaye yenza ntoni

Umxholo

• Yenzelwe ntoni
• Xa ungasebenzisi
• Kusetyenziswa kwanjani
• Iziphumo ebezingalindelekanga ezinokwenzeka
• Xa uvavanyo lwe-calcitonin lwenziwe

I-Calcitonin yihomoni eveliswe kwi-thyroid enomsebenzi wokunciphisa ukuxinwa kwe-calcium egazini, ukunciphisa ukufunxeka kwe-calcium ngamathumbu kunye nokukhusela umsebenzi we-osteoclasts.

Ke, i-calcitonin ibaluleke kakhulu ekugcineni impilo yethambo, yiyo loo nto kukho iziyobisi ezineli hormone ekwakhiweni, ezisetyenziswa kwizifo ezinjenge-osteoporosis, isifo sikaPaget okanye isifo sikaSudeck, umzekelo.

Yenzelwe ntoni

Iziyobisi zeCalcitonin zisetyenziselwa ukunyanga izifo ezinje:

• I-Osteoporosis, okanye iintlungu zethambo ezinxulumene noko, apho amathambo acekeceke kakhulu kwaye abuthathaka;
• Isifo sikaPaget sethambo, esisifo esicothayo nesinenkqubela phambili esinokubangela utshintsho kubungakanani kunye nokumila kwamathambo athile;
• Hypercalcemia, nto leyo luphawulwa eliphezulu kakhulu calcium egazini;
• I-Reflex ye-dystrophy yesifo, esisifo esibangela iintlungu kunye notshintsho lwethambo, olunokuthi lubandakanye ukuphulukana nethambo lendawo.

ICalcitonin inomsebenzi wokulawula amanqanaba e-calcium egazini kwaye ke isetyenziselwa ukubuyisa ukubola kwethambo. Ukongeza, kukholelwa ukuba le hormone ikwabandakanyeka ekwakheni amathambo.

Xa ungasebenzisi

Ngokubanzi, i-calcitonin esetyenziselwa amayeza kule hormone yi-salmon calcitonin, yiyo loo nto ichasene nabantu abanesifo sokungavunyelwa yile nto, okanye elinye nelinye ifomula.

Ukongeza, ayikhuthazwanga into yabasetyhini abakhulelweyo, abancancisayo kunye nabantu abangaphantsi kweminyaka eli-18 ubudala.

Kusetyenziswa kwanjani

Idosi ekhuthazwayo yecalcitonin ixhomekeke kwingxaki eza kunyangwa:

• I-Osteoporosis: Idosi ekhuthazwayo yi-50 IU ngemini okanye i-100 ye-IU ngosuku okanye yonke imihla, ngenaliti yangaphantsi okanye yentsimbi.
• Intlungu yethambo: Idosi ekhuthazwayo yi-100 ukuya kwi-200 IU, ngemini ngokufakwa kancinci kwisisombululo se-saline yomzimba okanye ngenaliti yesikhumba okanye yesitofu, kwiidosi ezahluliweyo, zisasazwa imini yonke, de kufumaneke impendulo eyonelisayo.
• Isifo sikaPaget: Idosi ekhuthazwayo yi-100 IU ngemini okanye yonke imihla, ngenaliti yangaphantsi okanye yangaphakathi.
• Unyango olungxamisekileyo lweengxaki ze-hypercalcemic: Idosi ekhuthazwayo yi-5 ukuya kwi-10 IU ngekhilogram yesisindo somzimba ngosuku, ngokufakwa ngaphakathi, okungenani iiyure ezi-6, okanye ngenaliti efakwa kancinci kwi-2 ukuya kwi-4 yedosi eyahlulwe ngosuku.
• Unyango olude lwe-hypercalcemia enganyangekiyo: Ithamo elicetyiswayo li-5 ukuya kwi-10 IU ngekhilogram yesisindo somzimba ngosuku, ngenaliti engaphantsi okanye ngenaliti, kwidosi enye okanye kwiidosi ezimbini ezahluliweyo.
• I-Reflex ye-dysstrophy yempawu: Idosi ekhuthazwayo yi-100 IU ngemini ngenaliti engaphantsi okanye ye-intramuscular kwiiveki ezi-2 ukuya kwezi-4.

Kuxhomekeke kugqirha ukufumanisa ukuba unyango kufuneka luqhubeke ixesha elingakanani.

Iziphumo ebezingalindelekanga ezinokwenzeka

Iziphumo ezibi ezixhaphakileyo ezinokubakho ngokusetyenziswa kwecalcitonin sisiyezi, iintlungu, ukutshintsha incasa, ukuba bomvu kobuso okanye kwentamo, isicaphucaphu, urhudo, iintlungu esiswini, ithambo okanye iintlungu ezidibeneyo nokudinwa.

Ukongeza, nangona kuncinci rhoqo, ukuphazamiseka kombono, uxinzelelo lwegazi oluphezulu, ukugabha, iintlungu kwimisipha, amathambo okanye amalungu, iimpawu zomkhuhlane kunye nokudumba kweengalo okanye imilenze nako kunokubakho.

Xa uvavanyo lwe-calcitonin lwenziwe

Uvavanyo lokulinganiswa kwamaxabiso e-calcitonin luboniswa ikakhulu ekuchongeni nasekujongeni ubukho be-medullary thyroid carcinoma, isifo esibangela ukuphakama okubalulekileyo kwale hormone.

Ukongeza, i-calcitonin inokuba luncedo ekuchongeni ezinye iimeko, ezinje nge-hyperplasia yeeseli ze-thyroid, eziziiseli ezivelisa i-calcitonin, kunye nokuhamba nezinye iintlobo zomhlaza, ezinjenge-leukemia, umhlaza wemiphunga, ibele, injeke okanye Prostate, umzekelo. Fumanisa ngakumbi malunga nokuba yintoni uvavanyo lwe-calcitonin kwaye lwenziwa njani.