Ngaba iCaffeine inokuchaphazela izicubu zebele?

Umxholo

• Caffeine kunye nezicubu zamabele ezixineneyo
• Yintoni ekwikhafeyini enokuchaphazela izicwili zamabele?
• Kuthetha ukuthini ukuba nezicubu zamabele ezixineneyo?
• Wazi njani ukuba unezicubu zamabele ezixineneyo?
• Ukuxinana kwebele kunye nomngcipheko womhlaza wamabele
• Cinga ngovavanyo lwe-ultrasound lonyaka
• Cinga ukuhlolwa konyaka kweMRI
• Umngcipheko wokuvavanya amabele kunye nezibonelelo
• Ngaba unokunciphisa ukuxinana kwebele?
• Caffeine kunye nomhlaza webele
• Iindlela zokuthatha eziphambili

Impendulo emfutshane nguewe. I-caffeine inokuchaphazela izicubu zebele. Nangona kunjalo, icaffeine ayibangeli umhlaza wamabele.

Iinkcukacha zinzima kwaye zinokudideka. Eyona nto iphambili kukuba unxibelelwano phakathi kweCaffeine kunye nethishu yamabele akufuneki ukuba itshintshe ikofu okanye imikhwa yokusela iti.

Nantsi into esiyaziyo, ngokufutshane:

• I-caffeine ayisiyongxaki yomhlaza webele.
• Kunokubakho encinci umbutho phakathi koxinano lweethishu zamabele kunye necaffeine. Oku akuthethi ukuba unobangela.
• Izifundo ezininzi ziye zagqitywa kwelokuba izicwili ezomeleleyo zamabele ngumhlaza webele.

Kule nqaku, siza kujonga ngakumbi kwi-caffeine, ukuxinana kwebele, kunye nokudibanisa phakathi kobunzima besifuba kunye nomhlaza wesifuba.

Caffeine kunye nezicubu zamabele ezixineneyo

Zimbalwa kakhulu izifundo zecaffeine kunye nezicubu zesisu, kwaye iziphumo zixubekile.

Akufumaniswanga mbutho wecaffeine kuxinano lwebele. Kwangokunjalo, ulutsha olufikisayo olutye i-caffeine alufumananga nxu lumano lokuxinana kwamabele kubafazi be-premenopausal.

Nangona kunjalo, umbutho ufumene umanyano oluncinci phakathi kokutya i-caffeine kunye nokuxinana kwebele. Iziphumo zophando zahlukile, kuxhomekeka ekubeni ingaba abafazi bebengaphambi kokuba baye kwi-premenopausal okanye be-postmenopausal:

• Abafazi be-Postmenopausal abane-caffeine ephezulu okanye i-decaffeinated coffee intake babenepesenti esezantsi yokuxinana kwethishu yamabele.
• Abafazi be-Premenopausal abanokutya okuphezulu kwekofu babeneepesenti ephezulu yokuxinana kwamabele.
• Abafazi be-Postmenopausal kunyango lwehomoni ababenekofu ephezulu kunye nokutya kwe-caffeine babenepesenti esezantsi yokuxinana kwamabele. Ngenxa yokuba unyango lwehomoni ludla ngokunxulunyaniswa nokunyuka kobuninzi bebele ngokubanzi, uphononongo lubonisa ukuba ukutya i-caffeine kunokunciphisa oku.

Yintoni ekwikhafeyini enokuchaphazela izicwili zamabele?

Unxibelelwano phakathi kwe-caffeine kunye nokuxinana kwamathambo ebele akuqondakali ngokupheleleyo.

Kucetyiswa ukuba uninzi lweebhayoloji ezisebenzayo zebhayoloji (ii-phytochemicals) kwi-caffeine inokukhuthaza ii-enzymes ezichaphazelekayo kwi-estrogen metabolism kunye nokunciphisa ukudumba. Ezi phytochemicals zinokuthintela ukukhutshelwa kohlobo ngokufaka amaqela e-methyl kwiimolekyuli ze-DNA.

Kuvavanyo lwezilwanyana, iikhompawundi zekofu zacinezela ukwenziwa kwamathumba ebele, njengoko kuxeliwe kuphando lwe-2012 lwecaffeine kunye nomhlaza webele. Uphononongo luka-2015 lufumanise ukuba icaffeine kunye necaffeic acid yayineempawu ze-anticancer ngokunxulumene ne-estrogen receptor genes.

Kuthetha ukuthini ukuba nezicubu zamabele ezixineneyo?

Ukuba namabele ashinyeneyo kuthetha ukuba unezicubu ezinemicu engaphezulu okanye ezinamaqhuqhuva kwaye hayi amanqatha amaninzi kumabele akho. Phantse isiqingatha sabasetyhini baseMelika banamabele axineneyo. Yinto eqhelekileyo.

Zine iindidi zoxinano lwebele njengoko kuchaziwe:

• (A) phantse onke amanqatha amabele
• (B) iindawo ezisasazekileyo zesisindo esinyeneyo
• (C) eyahlukileyo (ngokungafaniyo) izicubu zamabele ezixineneyo
• (D) izicwili zamabele ezixineneyo

Malunga nabasetyhini bawela kudidi C kwaye malunga nodidi D.

Amabele ashinyeneyo aqheleke ngakumbi kubafazi abancinci nakwabasetyhini abanamabele amancinci. Phantse kwikota yesithathu yabasetyhini kwi-30s yabo banezicubu zesifuba ezixineneyo, xa kuthelekiswa nekota enye yabasetyhini kwi-70s yabo.

Kodwa nabani na, nokuba ungakanani ubungakanani besifuba okanye ubudala, unokuba namabele ashinyeneyo.

Wazi njani ukuba unezicubu zamabele ezixineneyo?

Awunakuva uxinano lwebele, kwaye aluhambelani nokuqina kwebele. Ayinakufunyanwa kuvavanyo lomzimba. Olona hlobo kuphela lokubona ubungakanani beethishu zamabele kukwimammogram.

Ukuxinana kwebele kunye nomngcipheko womhlaza wamabele

Ukuxinana kwamathambo ebele kusekwe kakuhle njenge. Umngcipheko uphezulu ngepesenti ye-10 yabasetyhini abanamabele axineneyo kakhulu.

Nangona kunjalo, ukuba namabele ashinyeneyo akuthethi ukuba uya kuba nomhlaza wamabele. Ukuxhalaba ngamabele ashinyeneyo kukuba nokuba i-mammogram ye-3-D (ebizwa ngokuba yidijithali yencasa yamabele) inokuphosa umhlaza okhulayo kwizicubu zamabele ezixineneyo.

Kuqikelelwa ukuba ukuya kuthi ga kwiipesenti ezingama-50 zomhlaza wamabele azinakubonwa kwi-mammogram kwabasetyhini abanamabele ashinyeneyo.

Cinga ngovavanyo lwe-ultrasound lonyaka

Ukuba i-mammogram yakho ibonisa ukuba unesisindo esinyeneyo sesifuba, ngakumbi ukuba ngaphezulu kwesiqingatha sezicubu zakho zebele zixinene, thetha ngovavanyo lwakho lonyaka lwe-ultrasound nogqirha wakho.

Iimviwo ze-ultrasound zesifuba zibona ii-tumors ezongezelelweyo ezi-2 ukuya kwezi-4 kwabasetyhini abayi-1 000 abahlolwa ziimammograms.

Cinga ukuhlolwa konyaka kweMRI

Kubafazi abanomngcipheko ophezulu womhlaza webele osuka kwizicubu zesifuba esixineneyo okanye ezinye izinto ezinobungozi, xoxa nogqirha wakho malunga nokuvavanywa kweMRI minyaka le. I-MRI yebele ifumana umndilili wee-10 zomhlaza ezongezelelweyo kwabasetyhini abayi-1 000, kwanasemva kovavanyo lwe-mammogram kunye nokuvavanywa kwe-ultrasound.

Ukuba awunayo i-mammogram, awukwazi ukuba unobungozi obuninzi bomhlaza wesifuba ekubeni ube namabele aminyene, isithethi seNational Cancer Institute (NCI) sigxininisa. Abasetyhini kufuneka baxoxe ngembali yosapho kunye nezinye izinto ezinobungozi kunye nomboneleli wabo wezempilo ukumisela ishedyuli ye-mammogram efanelekileyo kubo.

Umngcipheko wokuvavanya amabele kunye nezibonelelo

Nokuba ngaba kufuneka ube novavanyo lonyaka lokuvavanywa kwamabele ukuba unamabele ashinyeneyo sisigqibo esizimeleyo. Xoxa ngokulungileyo kunye nokubi kunye nogqirha.

Ukongezwa kokuvavanywa komhlaza webele kwiibele ezixineneyo. Kwaye ukubamba umhlaza wamabele kwasekuqaleni kunesiphumo esingcono.

I-US Preventive Services Task Force yacebisa ngo-2016 ukuba ubungqina obukhoyo ngoku abonelanga "ukuvavanya ibhalansi yezibonelelo kunye nokwenzakala" kokongezwa kwesikrini kwabasetyhini abanamabele ashinyeneyo. Izinto ezinokubakho zibandakanya:

• Iimpembelelo zobuxoki ezinokwenzeka
• usulelo lwe-biopsy
• unyango olungeyomfuneko
• umthwalo wengqondo

Iziko lewebhu le-densebreast-info.org lijonga iingenelo kunye neengozi zovavanyo.

Unokufumana ulwazi ngakumbi malunga nokujonga kwisikhokelo sesigulana kukhetho lokujonga kwiwebhusayithi yombutho ongenzi nzuzo areyoudense.org.

Ngaba unokunciphisa ukuxinana kwebele?

"Awunakho ukutshintsha ukuxinana kwakho kwebele, kodwa unokujonga amabele akho nge-3-D mammogram kunye ne-ultrasound," utshilo uJoe Cappello, umlawuli olawulayo we-Are You Dense, Inc., uxelele i-Healthline.

Uhlalutyo lwabasetyhini abangama-18,437 abanesifo somhlaza webele bacebisa ukuba ukuncitshiswa koxinano lwethishu yamabele kunokuwanciphisa kakhulu amanani omhlaza wamabele. Kodwa oku kuya kufuna uphuhliso olutsha.

Abaphandi bacebisa ukuba ukuthoba uxinizelelo lwebele kunokufezekiswa ngokusetyenziswa kokuthintela kwabo bafazi bakumanqanaba aphezulu omngcipheko.

I-Tamoxifen sisiyobisi esichasene ne-estrogen. Kufunyenwe ukuba unyango lwe-tamoxifen lanciphisa uxinano lwebele, ngakumbi kwabasetyhini abangaphantsi kwe-45.

"Gcina ubunzima obusempilweni kwaye wenze umthambo rhoqo," ucebisa nge-NCI. “Zimbini izinto ezi uzenzayo unako yenza ukunciphisa umngcipheko womhlaza wamabele, nangona ungeke ukwazi ukutshintsha ukuxinana kwakho namabele okanye ukubakho kwakho kwimfuza kumhlaza wamabele. ”

Caffeine kunye nomhlaza webele

Iminyaka yophando ngecaffeine kunye nomhlaza webele ifumanise ukuba ukusela ikofu okanye ezinye iziselo ezinecafini ayinyusi umngcipheko womhlaza wamabele.

Le yimeko yabasetyhini abancinci nabadala. Kodwa ngenxa yezizathu ezingachazwanga ngokupheleleyo, ukutya okuphezulu kwe-caffeine kubonakala kunciphisa umngcipheko wesifo somhlaza wamabele kubafazi abasele besemaphathini.

Uphononongo luka-2015 lwabafazi abayi-1,090 eSweden abanesifo somhlaza webele bafumanisa ukuba ukusetyenziswa kwekofu kwakungadibani nesifo sonke. Kodwa abantu basetyhini abane-estrogen-receptor-positive type tumors abasele ezimbini okanye nangaphezulu iikomityi zekofu ngemini behle nge-49 yepesenti yokuphindaphinda komhlaza, xa kuthelekiswa nabasetyhini abafanayo abasela ikofu encinci.

Ababhali bophando luka-2015 bacebisa ukuba icaffeine kunye necaffeic acid zineempawu zokuthintela umdlavuza ezinciphisa ukukhula komhlaza wamabele ngokwenza izicubu ze-estrogen-receptor zibuthathaka ngakumbi kwi-tamoxifen.

Uphando oluqhubekayo lujonga ukuba zeziphi iipropathi zecaffeine ezinokuchaphazela umhlaza webele kunye nokuqhubela phambili komhlaza webele.

Iindlela zokuthatha eziphambili

I-Caffeine ayibangeli umhlaza webele, ngokwezifundo ezininzi zophando ngaphezulu kwamashumi eminyaka.

Kukho ubungqina obunqamlekileyo bentlangano encinci phakathi kwe-caffeine kunye nokuxinwa kwebele, okwahlukileyo kwabasetyhini be-premenopausal kunye ne-postmenopausal.

Ukuba neethishu ezixineneyo zesifuba yinto eyingozi yomhlaza webele. Abasetyhini abanezicubu zamabele ezixineneyo kufuneka babe ne-mammogram yonyaka kwaye baqwalasele ukuba neemvavanyo ezongezelelweyo zokuhlola. Ukufumanisa umhlaza webele kwangoko kukhokelela kwisiphumo esingcono.

Wonke umntu wasetyhini wahlukile, kwaye uchaphazeleka ngokwahlukeneyo ngumngcipheko womhlaza ofanayo. Iindaba ezimnandi zezokuba ngoku kukho ulwazi olwandisiweyo lomngcipheko womhlaza webele kunye noxinano lwebele.

Izixhobo ezininzi ezikwi-Intanethi zinokuphendula imibuzo kwaye zikunxibelelanise nabanye abantu basetyhini abahlangabezana nomngcipheko webele okanye umhlaza webele, kubandakanya areyoudense.org kunye nedensebreast-info.org. I-National Cancer Institute inemibuzo ephendulwayo.