ICarfilzomib: iyeza lomhlaza womongo wethambo

Umxholo

• Yenzelwe ntoni
• Kusetyenziswa kwanjani
• Iziphumo ebezingalindelekanga ezinokwenzeka
• Ngubani ongafanele asebenzise

ICarfilzomib sisiyobisi esingena ngenaliti esithintela amandla eeseli zomhlaza ekuveliseni nasekutshabalaliseni iiproteni, kuthintela ukuba zande ngokukhawuleza, nto leyo ethothisa ukukhula komhlaza.

Ke, eli yeza lisetyenziswa ngokudibeneyo ne-dexamethasone kunye ne-lenalidomide ukunyanga iimeko ze-myeloma ezininzi, uhlobo lomhlaza womongo wethambo.

Igama lokuthengisa eli yeza liyiKyprolis kwaye, nangona inokuthengwa kwiikhemesti eziqhelekileyo ngokubonisa amayeza, kufuneka ilawulwe kuphela esibhedlele phantsi kweliso likagqirha onamava kunyango lomhlaza.

Yenzelwe ntoni

Olu nyango luboniswa kunyango lwabantu abadala abane-myeloma eninzi abafumene ubuncinci uhlobo olunye lonyango lwangaphambili. I-Carfilzomib kufuneka isetyenziswe ngokudibanisa ne-dexamethasone kunye ne-lenalidomide.

Kusetyenziswa kwanjani

ICarfilzomib inokulawulwa kuphela esibhedlele ngugqirha okanye ngumongikazi, idosi ekucetyiswa ukuba iyahluka ngokobunzima bomntu ngamnye kunye nempendulo yomzimba kunyango

Esi sixhobo kufuneka silawulwe ngqo emthanjeni kangangemizuzu eli-10 ngeentsuku ezimbini ezilandelelanayo, kube kanye ngeveki kunye nakwiiveki ezi-3. Emva kwezi veki, kuya kufuneka uthathe ikhefu leentsuku ezili-12 kwaye uqale omnye umjikelo ukuba kukho imfuneko.

Iziphumo ebezingalindelekanga ezinokwenzeka

Ezinye zeziphumo ebezingalindelekanga zixhaphakileyo zibandakanya ukuba nesiyezi, iintloko, ukungalali, ukuncipha kokutya, ukunyuka koxinzelelo lwegazi, ukuphefumla kancinci, ukugabha, isifo sohudo, ukuqhina, iintlungu esiswini, isicaphucaphu, iintlungu ezidibeneyo, ukudumba kwezihlunu, ukudinwa kakhulu nokuba nomkhuhlane,

Ukongeza, kunokubakho iimeko zenyumoniya kunye nolunye usulelo lokuphefumla rhoqo, kunye notshintsho kumaxabiso ovavanyo lwegazi, ngakumbi kwinani leukocytes, erythrocytes kunye neeplatelets.

Ngubani ongafanele asebenzise

I-Carfilzomib akufuneki isetyenziswe ngabafazi abakhulelweyo okanye abancancisayo, kunye nabantu abangadibaniyo nakwezinye izinto zefomula. Ukongeza, kufuneka isetyenziswe ngononophelo kwaye iphantsi kolawulo lwezonyango kuphela xa isifo sentliziyo, iingxaki zemiphunga okanye ukuphazamiseka kwezintso.