Rhabdomyolysis: yintoni, iimpawu eziphambili kunye nonyango

Umxholo

• Iimpawu eziphambili
• Indlela yokuqinisekisa ukuxilongwa
• Yintoni ebangela i-rhabdomyolysis
• Unyango lwenziwa njani
• Iingxaki ezinokwenzeka

I-Rhabdomyolysis yimeko enzulu ebonakaliswa kukutshatyalaliswa kwemicu yemisipha, ekhokelela ekukhutshweni kwezinto ezikhoyo ngaphakathi kwiiseli zemisipha egazini, njengecalcium, isodiyam kunye ne potassium, myoglobin, creatinophosphokinase kunye ne-enzyme pyruvic transaminase (TGP). Izixa ezikhulu zezi zinto egazini zinokubangela ukunqongophala kwamandla, ukuncipha komchamo, ukudinwa kwezihlunu kunye nokusilela kwezintso, ukuba azichongwanga kwaye zanyangwa.

Njengokuba izinto ezikhutshiweyo zinetyhefu kumanani aphezulu, kubalulekile ukuba unyango luqaliswe ngokukhawuleza, kwaye kuyacetyiswa ukuba uye esibhedlele okanye kwigumbi likaxakeka ngokukhawuleza xa kurhaneleka irhabdomyolysis. I-Rhabdomyolysis inokwenzeka ngenxa yokuziqhelanisa nezinto ezomeleleyo kunye nokuhlala ixesha elide okanye njengesiphumo sengozi ethe ngqo okanye engathanga ngqo kwimisipha emzimbeni, kwaye kubalulekile ukuba uchonge unobangela ukuze unyango lujolise ngakumbi.

Iimpawu eziphambili

Iimpawu zerhabdomyolysis zinokwahluka ngokwenani elijikelezayo lee-enzymes ezikhutshwe ngaphakathi kwiiseli zemisipha, ezona mpawu ziqhelekileyo zezi:

• Ubuhlungu bemisipha;
• Ukungabi namandla;
• Kunzima ukuhambisa imilenze okanye iingalo zakho;
• Ukuqina kwemisipha;
• Intlungu edibeneyo;
• Ukuchama ngesixa esincinci kwaye kumnyama kakhulu, kuyafana nombala wecoca-cola.

Ukongeza kwezi mpawu, kunokuvela iimpawu ngokubanzi, ezinje ngomkhuhlane, isicaphucaphu, iintlungu esiswini, imvakalelo yokudinwa ngokubanzi, ukugabha, ukudideka kunye nokuphazamiseka. Kuba iimpawu ziyahluka ngokwesizathu, kunye nomzimba womntu ngamnye, kunokuba nzima kakhulu ukuchonga imeko ye-rhabdomyolysis.

Ke ngoko, ukuze i-rhabdomyolysis ichongwe kwaye kuthintelwe iingxaki, kubalulekile ukuba uye esibhedlele kuvavanyo oluthile lokuchonga isifo, ukuze sikwazi ukuqala unyango olufanelekileyo.

Indlela yokuqinisekisa ukuxilongwa

Ukuchongwa kwe-rhabdomyolysis kuhlala kwenziwa ngugqirha emva kokuvavanya iimpawu zomntu kunye nembali yonyango. Ukongeza, ugqirha ucebisa ukuba kwenziwe uvavanyo lwegazi kunye nomchamo ukujonga ubungakanani be-electrolyte ejikeleza egazini, kunye nokuxinana kwe-myoglobin, creatine phosphokinase kunye ne-TGP. Ngokusebenzisa umchamo, ugqirha unokuvavanya isixa se-myoglobin, kubalulekile ukwazi ubungakanani be-rhabdomyolysis kwaye ukuba kukho imiqondiso ebonisa ukusilela kwezintso.

I-Myoglobin yenye yeemviwo eziphambili ezicelwe ngugqirha, kuba xa kutshatyalaliswa intsholongwane yemisipha, kokukhona isixa semyoglobin sikhutshelwa egazini nasemchameni, sishiya mnyama. Ukongeza, inani elikhulu le-myoglobin ekhutshiweyo, kokukhona liya kuba nethuba elikhulu lokuthintelwa kweetyhubhu zezintso, ezinokuthi zikhokelele ekwenzakaleni kwe-tubular kwaye, ngenxa yoko, ukusilela kwezintso. Funda ngakumbi malunga ne-myoglobin.

Yintoni ebangela i-rhabdomyolysis

I-Rhabdomyolysis ihlala isenzeka ngenxa yokuziqhelanisa nomsebenzi onzima kunye nexesha elide, okhokelela kuxinzelelo lweemisipha ezigqithileyo. Ezinye izizathu zerhabdomyolysis zezi:

• Iingozi ezimandundu, njengokuwa okuphezulu okanye iingozi zendlela;
• Ukusetyenziswa ixesha elide kwamayeza athile, ngakumbi ii-antipsychotic okanye ii-statins;
• Ukusetyenziswa kweziyobisiikakhulu icocaine, heroin okanye amphetamines;
• Ukuhamba ixesha elide ngenxa yokufa isiqaqa okanye ukugula;
• Usulelo, ezinokuthi zikhokelele ekufumaneni ityhefu emzimbeni, oyena nobangela uphambili werhabdomyolysis ebantwaneni;
• Izifo zemisipha, ezinje nge-myopathy kunye nepoliyo;
• Guqula kubushushu bomzimba.

Ukongeza, i-rhabdomyolysis inokuthi yenzeke njengesiphumo sokusela kakhulu iziselo ezinxilisayo, ukothuka ngombane, izifo ze-metabolic kunye ne-stroke.

Unyango lwenziwa njani

Xa i-rhabdomyolysis ingenangxaki, ihlala isombulula kwiintsuku ezimbalwa ukuya kwiiveki. Nangona kunjalo, kwezinye iimeko kunokuba yimfuneko ukuba kwenziwe unyango kunye nomntu ongeniswe esibhedlele ukuze i-serum inikwe ngqo emthanjeni ukunqanda iingxaki ezinzulu zesifo, ezinjengokuphelelwa ngamanzi emzimbeni okanye ukusilela kwezintso, okubangelwa yimisipha engaphezulu inkunkuma egazini.

Ukongeza, kubalulekile ukuba uchaze unobangela werhabdomyolysis ukuqala unyango olufanelekileyo, ukuba kukho imfuneko. Ke, ukuba kubangelwa kukusetyenziswa kwalo naliphi na iyeza, umzekelo, kuya kufuneka uyeke ukuselwa kwaye utshintshele kwelinye iyeza ngokwengcebiso yezonyango.

Ixesha lonyango liyohluka ngokonobangela kunye nokuvela kwesigulana, kwaye ngexesha lokulaliswa esibhedlele kufuneka ubotshelelwe ukuvavanya isixa somchamo ngemini kwaye wenze olunye uvavanyo lwezintso ukuqinisekisa ukuba umsebenzi wezintso awuchaphazeleki. Isigulana sihlala sikhululwa xa iimvavanyo ziqhelekile kwaye akukho bungozi bokusilela kwezintso.

Kwiimeko ezinzima kakhulu, apho izintso ziqala ukuvelisa umchamo omncinci, ugqirha unokuyalela i-dialysis ukunceda ukusebenza kwezintso, ukuphelisa izinto ezingaphezulu kwegazi ezinokwenza unyango lube nzima.

Iingxaki ezinokwenzeka

Eyona ngxaki inzima nexhaphakileyo ye-rhabdomyolysis kukubonakala komonakalo wezintso, onokuthi ekugqibeleni ubangele ukusilela kwezintso. Nangona kunjalo, ubukho beentsalela egazini kukwakhokelela ekwandeni kwamanqanaba e-potassium kunye ne-phosphorus emzimbeni, onokuthi ugqibe ngokuchaphazela ukusebenza kwentliziyo.

Kwiimeko ezinqabileyo, esinye isifo esaziwa njenge gumbi lesifo sinokuvela, apho ukujikeleza kwegazi kuthintelwa kwingingqi yomzimba, njengemilenze, iingalo okanye izihlunu ezithile zesisu, ezibangela ukubulawa sisisu. Qonda ukuba yintoni isifo secandelo.