Nantsi into ekufuneka uyazi malunga ne-COVID yeempembelelo zecandelo lokugonya ukuba unee-cosmetic fillers

Umxholo

• Okokuqala, ixhaphake kangakanani le mpembelelo isecaleni kwisitofu sokugonya?
• Kutheni le nto umntu onezalisa enokuthi adumbe emva kokufumana isitofu sokugonya se-COVID-19?
• Yintoni omawuyenze ukuba uneeFilisi kwaye uCwangcise lokufumana uGonyo lwe-COVID-19
• Uphengululo lwe

Kungekudala ngaphambi konyaka omtsha, uLawulo lwezoKutya kunye noLawulo lweeDrama luchaze umphumo wecala lokugonya le-COVID-19 elitsha: ukudumba kobuso.

Abantu ababini-oneminyaka engama-46 ubudala kunye no-51-owafumana iyeza lokugonya le-Moderna COVID-19 ngexesha lovavanyo lwezonyango abanamava "okunxulumana okwethutyana" (intsingiselo kwicala lobuso) ukudumba zingaphelanga iintsuku ezimbini zokufumana ithamo labo lesibini lokudubula, ngokwengxelo. Isizathu esikrokrelwayo sokudumba? Izinto zokuthambisa zokuthambisa. "Zombini ezi zifundo bezine-dermal filler ngaphambili," utshilo i-FDA kwingxelo. I-arhente ayizange yabelane ngolwazi olungakumbi, kwaye umbhexeshi weModerna akazange abuye UbumeIsicelo sokufaka izimvo phambi kokupapashwa.

Ukuba uneefiller zokuthambisa okanye ubuzithathela ingqalelo, mhlawumbi unemibuzo malunga nokuba ungalindela ntoni na xa ufumana isitofu sokugonya se-COVID-19- nokuba sivela eModerna, Pfizer, okanye naziphi na ezinye iinkampani ezinokuthi kungekudala zifumane isigunyaziso sokusetyenziswa ngokungxamisekileyo I-FDA. Nantsi into ekufuneka uyazi.

Okokuqala, ixhaphake kangakanani le mpembelelo isecaleni kwisitofu sokugonya?

Hayi kakhulu. Ukudumba kobuso akufakwanga kuluhlu lweziphumo ebezingalindelekanga ze-COVID-19 zokugonya ezivela kumaziko oLawulo lweZifo noThintelo. Kwaye i-FDA ibhale nje iingxelo ezimbini zeli cala ngaphandle kwabantu abangaphezu kwama-30,000 abathathe inxaxheba kuvavanyo lweklinikhi yaseModerna (ukuza kuthi ga ngoku, iziphumo ebezingalindelekanga azichazwanga ngogonyo lukaPfizer okanye naziphi na izitofu ze-COVID-19 zenkampani).

Oko kwathiwa, STAT, indawo yeendaba zonyango ethi ibhlogi ye-FDA ibonakalise le datha ngoDisemba, uxele umntu wesithathu kwityala laseModerna abathi baphuhlise i-lip angioedema (ukudumba) malunga neentsuku ezimbini emva kogonyo (akucaci nokuba emva komntu wokuqala okanye idosi yesibini). "Lo mntu ufumene inaliti yokuzalisa i-dermal ngaphambili emlonyeni," utshilo uRachel Zhang, MD, igosa lezonyango le-FDA, ngexesha lenkcazo, ngokutsho. STAT. UGqirha Zhang khange achaze ukuba lo mntu uyifumene nini inkqubo yokugcwalisa. (Inxulumene: Yonke into ekufuneka uyazi malunga ne-COVID-19 Iziphumo zeNtsholongwane)

Ngelixa i-FDA ingatshongo ukuba bangaphi abantu abakwilingo leModerna abanokuzalisa izithambiso, phantse abantu abazizigidi ezi-3 e-US bafumana iifilitha minyaka le, ngokwe American Society of Plastic Surgeons- ke, yinkqubo eqhelekileyo. Kodwa ngeziganeko ezithathu kuphela zokudumba kobuso kulingo olubandakanya abantu abangaphezu kwama-30,000, oko kuthetha ukuba kukho ithuba eli-1 kwi-10,000 lokuphuhlisa ukudumba kobuso emva kokufumana iyeza le-COVID-19. Ngamanye amazwi: Akunakwenzeka.

Kutheni le nto umntu onezalisa enokuthi adumbe emva kokufumana isitofu sokugonya se-COVID-19?

Esona sizathu asikacaci okwangoku, kodwa ukudumba "yinto ethile esebenzayo phakathi kwesitofu sokugonya kunye nezithako ezisizalisayo," utshilo u-Amesh A. Adalja, ingcali yesifo esosulelayo kwiziko iJohn Hopkins Centre Ukhuseleko lwezeMpilo.

Izithako zokugonya zeModerna zibandakanya i-mRNA (imolekyuli efundisa umzimba wakho ukuba yenze uhlobo lwayo lwe-COVID-19 protein's spike protein njengendlela yokulungiselela umzimba wakho ukuzikhusela kwintsholongwane), iintlobo ezahlukeneyo zeep lipids (amafutha ukunceda ukuthwala i-mRNA iye kwiiseli ezichanekileyo), i-tromethamine kunye ne-tromethamine hydrochloride (alkalizers ezisetyenziswa kakhulu kwizitofu zokunceda ukulinganisa inqanaba le-pH lokugonya kunye nemizimba yethu), i-acetic acid (i-asidi yendalo efumaneka kwiviniga inceda ukugcina uzinzo lwe-pH ukuzinza), i-acetate ye-sodium (uhlobo lwetyuwa olusebenza njengenye ye-pH stabilizer ye-vaccine kwaye isetyenziswa rhoqo kwi-IV fluid), kunye ne-sucrose (aka iswekile- sesinye isithako esiqinisekisayo sezitofu ngokubanzi) .

Ngelixa enye ye-lipids yesitofu sokugonya, i-polyethylene glycol, iye yanxulunyaniswa neempendulo zexesha elidlulileyo, uGqirha Adalja uthi kunzima ukwazi ukuba ingaba esi sithako-okanye nayiphi na enye into-ibandakanyeka ngokukodwa kukudumba kwabantu abagcwalisa.

Ingxelo ye-FDA ayikhange ichaze ngokuthe ngqo ukuba loluphi uhlobo lwezinto zokuthambisa ezizifumeneyo ezi zigulana. IAmerican Academy of Dermatology ithi ezona zinto zixhaphakileyo zizalisa, zithatha amanqatha athathwe emzimbeni wakho, i-hyaluronic acid (iswekile efumaneka ngokwendalo emzimbeni enika ukonakala kolusu, ukubhampa, kunye nokuqaqamba), i-calcium hydroxylapatite (ngokusisiseko ifom ye-calcium enokufaka inaliti yokunceda ukuvelisa ulusu lwe-collagen), i-poly-L-lactic acid (i-asidi ekonyusa ukwenziwa kwe-collagen), kunye ne-polymethylmethacrylate (enye i-collagen booster). Nganye kwezi zigcwalisi inokuza neziphumo zayo ezizodwa kunye neempendulo ezinqamlezayo. Kodwa kuba i-FDA khange icacise ukuba loluphi uhlobo (okanye iintlobo) zokugcwalisa aba bantu babenazo, "akucaci ukuba yeyiphi na into enokuphinda isebenze," utshilo uGqirha Adalja. "Ininzi imibuzo efuna ukuphendulwa." (Idibeneyo: Isikhokelo esipheleleyo kwii-Injection Filler)

Okubangela umdla kukuba, umntu oye wafumana ukudumba kwemilebe emva kogonyo lweModerna COVID-19 uthe "babenempendulo efanayo emva kwesitofu sokugonya umkhuhlane wangaphambili," utshilo uGqr. STAT.

Enye inkcazo enokubakho yempembelelo esecaleni- nokuba yeyokugonya kwe-Moderna ye-COVID-19, iflu shot, okanye nasiphi na esinye isitofu-kukuba "ukwenziwa kwenkqubo yomzimba yokuzikhusela ngogonyo nako kunokubangela ukudumba kwezinye iisayithi emzimbeni, "utshilo uJason Rizzo, MD, Ph.D., umlawuli we-Mohs Surgery kwiNtshona yeNew York Dermatology. "Ekubeni i-dermal filler iyinto yangaphandle emzimbeni, iyavakala ukuba ezi ndawo ziya kuba lula ukudumba kunye nokudumba kolu hlobo lwemeko," uyacacisa. (FYI: I-Dermal filler ayifani neBotox.)

Yintoni omawuyenze ukuba uneeFilisi kwaye uCwangcise lokufumana uGonyo lwe-COVID-19

Idatha engaphezulu iyaqokelelwa kwiziphumo ebezingalindelekanga ze-COVID-19 xa iyonke, kodwa kubalulekile ukuba unikele ingqalelo kwinto exeliweyo ukuza kuthi ga ngoku-kunye neziphumo ebezingalindelekanga eziye zabonwa kuphela kumanani amancinci kakhulu. Unoko engqondweni, uGqirha Adalja uthi licebo elihle ukuthetha nodokotela wakho ophambili ukuba uneefiller kwaye uceba ukugonyelwa i-COVID-19.

Ukuba ufumana ukuqhubela phambili, qiniseka ukuba uxhoma kwiofisi yakho yezonyango malunga nemizuzu engama-15 ukuya kwe-30 emva kokuba ugonyiwe. (Umboneleli wakho kufuneka alandele izikhokelo ze-CDC kwaye acebise oku kunjalo, kodwa akukaze kube buhlungu ukuphinda.) "Ukuba ufumana ukuvuvukala, kunokunyangwa nge-steroids okanye i-antihistamines, okanye indibaniselwano ethile," kusho uDkt Adalja. Ukuba kunokwenzeka ukuba uhlakulele ukudumba kobuso (okanye nayiphi na into engalindelekanga, malunga naloo nto) emva kokuba ugonyiwe kwaye ushiye indawo yokugonya, uGqirha Adalja ucebisa ukuba ubize ugqirha wakho ASAP ukuze ufumane unyango olululo.

Kwaye, ukuba ubona ukudumba kobuso (okanye nayiphi na enye malunga neziphumo ebezingalindelekanga) emva kwedosi yokuqala yesitofu sakho sokugonya se-COVID-19, qiniseka ukuba uthetha nogqirha wakho malunga nokuba luluvo olulungileyo na ukufumana idosi yesibini, utshilo uRajeev Fernando. , MD, ingcali yesifo esosulelayo esebenza kwizibhedlele ze-COVID-19 kwilizwe lonke. Kwakhona, ukuba ukhathazekile malunga nento enokubangela ukudumba, uGqirha Fernando ucebisa ukuba uthethe ne-allergist, onokuthi akwazi ukuqhuba iimvavanyo ezithile ukuze abone ukuba yintoni enokubangela isiphumo esibi.

Ugqirha Adalja ugxininisa ukuba ezi ndaba akufuneki zikugcine ekugonyweni, nokuba unayo okanye ucinga ngokufumana iifiller kungekudala. Kodwa, uthi, "unokufuna ukuzikhumbula ngakumbi iimpawu ozifumanayo emva kokufumana isitofu sokugonya, ukuba sikhona, kwaye ujonge indawo apho wawuzalise khona."

Ngokubanzi, nangona kunjalo, uGqirha Adalja uthi "umngcipheko womyinge wenzuzo uthanda ukufumana isitofu sokugonya."

Uthi: "Singanyanga ukudumba," kodwa asinakusoloko siphatha ngempumelelo i-COVID-19.

Ulwazi kweli bali luchanekile ngexesha lokushicilelwa. Njengoko uhlaziyo malunga ne-coronavirus ye-COVID-19 luqhubeka nokuvela, kunokwenzeka ukuba ezinye iinkcukacha kunye nezindululo kweli bali zitshintshile ukusukela ekupapashweni kwayo. Siyakukhuthaza ukuba ujonge rhoqo ngezixhobo ezinjenge-CDC, i-WHO, kunye nesebe lezempilo likarhulumente kwindawo yakho yokufumana olona lwazi lwanamhlanje kunye neengcebiso.

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