Unyango lweSecondary Acute Myeloid Leukemia Treatment: Yintoni oza kuyibuza ugqirha wakho

Umxholo

• Zeziphi iindlela zonyango endinokukhetha kuzo?
• Ziziphi iingozi ezinokubakho?
• Ndidinga uluvo lwesibini?
• Loluphi uhlobo lokulandela endiza kulufuna?
• Ndingalindela ntoni?
• Zithini izinto endinokukhetha ukuzenza ukuba unyango alusebenzi okanye i-AML yam iyabuya?
• Yise kude

I-leukemia ye-myeloid Acute (AML) ngumhlaza ochaphazela umongo wethambo lakho. Kwi-AML, umongo wethambo uvelisa iiseli ezimhlophe zegazi ezingaqhelekanga, iiseli ezibomvu zegazi, okanye iiplatelets. Iiseli ezimhlophe zegazi zilwa nosulelo, iiseli ezibomvu zegazi zithwala ioksijini kuwo wonke umzimba, kwaye iiplatelets zinceda ukujiya kwegazi.

I-AML yesibini yinto encinci yalo mhlaza ochaphazela abantu:

• owayenomhlaza womongo wethambo kwixa elidlulileyo
• owayenonyango lwe-chemotherapy okanye unyango lwe-radiation
  omnye umhlaza
• abaneziphazamiso zegazi ezibizwa ngokuba yi-myelodysplastic
  syndromes
• abanengxaki nomongo wethambo lowo
  kubangela ukuba lenze iiseli ezibomvu ezininzi kakhulu, iiseli ezimhlophe zegazi, okanye iiplatelets
  (Iimpawu ze-myeloproliferative neoplasms)

I-AML yesibini inokuba nzima ukunyanga, kodwa zininzi iindlela onokukhetha kuzo. Yiza nale mibuzo kwindawo yakho elandelayo kunye nogqirha wakho. Xoxa ngalo lonke ukhetho lwakho ukuqinisekisa ukuba uyazi ukuba ulindele ntoni.

Zeziphi iindlela zonyango endinokukhetha kuzo?

Unyango lwe-AML yesibini luhlala lufana ne-AML yesiqhelo. Ukuba ufunyaniswe une-AML ngaphambili, unokufumana unyango olufanayo kwakhona.

Eyona ndlela iphambili yokunyanga i-AML yesibini kukunyanga ngamayeza. La machiza anamandla abulala iiseli zomhlaza okanye ayeke ukwahlulahlula. Basebenza kumhlaza emzimbeni wakho wonke.

Amachiza e-anthracycline anje nge-daunorubicin okanye i-idarubicin ahlala esetyenziselwa i-AML yesibini. Umboneleli wakho wezempilo uya kufaka intsholongwane ngamachiza e-chemotherapy kwisithambo sengalo yakho, phantsi kolusu lwakho, okanye kulwelo olujikeleze intambo yakho yomqolo. Unokuthatha la machiza njengeepilisi.

Ukufakelwa kweseli ye-allogenic stem lolunye unyango oluphambili, kwaye lolona lusenokwenzeka ukunyanga i-AML yesibini. Okokuqala, uya kufumana iidosi eziphezulu kakhulu zekhemotherapy ukubulala iiseli zomhlaza ezininzi kangangoko kunokwenzeka. Emva koko, uya kufumana ukumiliselwa kweeseli zomongo wethambo ezisuka kumnikeli ophilileyo ukubuyisela iiseli ezilahlekileyo.

Ziziphi iingozi ezinokubakho?

I-Chemotherapy ibulala iiseli ezahlula-hlula umzimba wakho wonke. Iiseli zomhlaza zikhula ngokukhawuleza, kodwa iiseli zeenwele, iiseli zomzimba, kunye nezinye iintlobo zeeseli ezisempilweni. Ukuphulukana nezi seli kungakhokelela kwiziphumo ebezingalindelekanga ezinje:

• ukulahleka kweenwele
• izilonda zomlomo
• ukudinwa
• isicaphucaphu nokugabha
• ukungabi namdla wokutya
• urhudo okanye ukuqhina
• Usulelo oluninzi kunesiqhelo
• ukugruzuka okanye ukopha

Iziphumo ebezingalindelekanga oxhomekeke kuzo kwichiza le-chemotherapy olithathayo, idosi, kunye nendlela umzimba wakho ophendula ngayo kuyo. Iziphumo ebezingalindelekanga kufuneka zihambe xa unyango lwakho ligqityiwe. Thetha nogqirha wakho malunga nendlela yokulawula iziphumo ebezingalindelekanga ukuba unazo.

Ukufakelwa kweseli kwistem kunika elona thuba lilungileyo lokunyanga i-AML yesibini, kodwa inokuba neziphumo ebezingalindelekanga ezibi. Umzimba wakho unokubona iiseli zomnikeli njengezangaphandle kwaye uzihlasele. Oku kubizwa ngokuba sisifo se-graft-versus-host host (GVHD).

I-GVHD inokonakalisa amalungu afana nesibindi kunye nemiphunga, kwaye ibange iziphumo ebezingalindelekanga ezinje:

• iintlungu zemisipha
• iingxaki zokuphefumla
• ubumthubi besikhumba nabamhlophe bamehlo
  (inyongo)
• ukudinwa

Ugqirha wakho uya kukunika amayeza ukunceda ukuthintela i-GVHD.

Ndidinga uluvo lwesibini?

Zininzi iintlobo ezahlukeneyo zalo mhlaza zikhona, ke kubalulekile ukuba ufumane uxilongo olufanelekileyo ngaphambi kokuba uqale unyango. I-AML yesibini inokuba sisifo esinzima kakhulu ukusilawula.

Kungokwemvelo ukufuna uluvo lwesibini. Ugqirha wakho akufuneki athuke ukuba ubuza omnye. Uninzi lwezicwangciso zeinshurensi yezempilo ziya kuhlawula umbono wesibini. Xa ukhetha ugqirha oza kujonga ukhathalelo lwakho, qiniseka ukuba banamava okunyanga uhlobo lwakho lomhlaza, kwaye uzive ukhululekile xa unabo.

Loluphi uhlobo lokulandela endiza kulufuna?

I-AML yesibini inokubuya-kwaye ihlala ibuya-emva konyango. Uya kulibona iqela lakho lonyango kutyelelo olulandelayo olulandelayo kunye neemvavanyo zokuyibamba kwangoko ukuba iyabuya.

Yazisa ugqirha wakho malunga naziphi na iimpawu ezintsha okhe wanazo.Ugqirha wakho unokukunceda ukuba ulawule naziphi na iziphumo ebezingalindelekanga ezinokubakho emva konyango lwakho.

Ndingalindela ntoni?

I-AML yesibini ayiphenduli kunyango kunye ne-AML ephambili. Kunzima ukufezekisa ukuxolelwa, oko kuthetha ukuba akukho bungqina bomhlaza emzimbeni wakho. Kuqhelekile ukuba umhlaza ubuye emva konyango. Elona thuba lakho lihle lokungena kuxolelo kukuba nokufakelwa kweseli kwistem.

Zithini izinto endinokukhetha ukuzenza ukuba unyango alusebenzi okanye i-AML yam iyabuya?

Ukuba unyango lwakho alusebenzi okanye umhlaza wakho ubuya, ugqirha wakho angakuqala kwichiza elitsha okanye unyango. Abaphandi bahlala befunda unyango olutsha ukuphucula imbonakalo ye-AML yesibini. Olunye lonyango lusebenza bhetele kunolo lukhoyo ngoku.

Enye indlela yokuzama unyango olutsha ngaphambi kokuba lufumaneke kuwo wonke umntu kukuba babhalise kuvavanyo lweklinikhi. Buza ugqirha wakho ukuba ngaba zikhona izifundo ezifanelekileyo ezifanelekileyo kuhlobo lwakho lwe-AML.

Yise kude

I-AML yesibini inokuba nzima ngakumbi ukunyanga kune-AML ephambili. Kodwa ngokufakelwa kweeseli ezinesiqu kunye nonyango olutsha oluphantsi kophando, kunokwenzeka ukuba ungene kuxolelo kwaye uhlale unjalo ixesha elide.