Idipyrone
Umxholo
- Yenzelwe ntoni
- Indlela yokuthatha
- 1. Ipilisi elula
- 2. Ithebhulethi esebenzayo
- 3. Isisombululo somlomo 500 mg / mL
- 4. Isisombululo somlomo 50 mg / mL
- 5. Ukuxhasa
- 6. Isisombululo ngenaliti
- Ingaba isebenza kanjani
- Iziphumo ebezingalindelekanga ezinokwenzeka
- Ngubani ongafanele asebenzise
- Kwiimeko zomkhuhlane, bubushushu obunjani ekufuneka buthathwe?
I-Dipyrone yi-analgesic, antipyretic kunye ne-spasmolytic, esetyenziswa kakhulu kunyango lwentlungu kunye nefiva, ihlala ibangelwa ngumkhuhlane kunye nomkhuhlane, umzekelo.
I-Dipyrone inokuthengwa kwiikhemesti eziqhelekileyo phantsi kwegama leNovalgina, iAnador, iBaralgin, iMagnopyrol okanye iNofebrin, ngohlobo lwethontsi, iipilisi, i-suppository okanye isisombululo esinokujova, ngexabiso elinokwahluka phakathi kwe-2 ukuya kwi-20 reais, kuxhomekeke idosi kunye nefom yokubonisa.
Yenzelwe ntoni
I-Dipyrone ibonakalisiwe kunyango lwentlungu kunye nomkhuhlane. Iziphumo ze-analgesic kunye ne-antipyretic zinokulindelwa kwimizuzu engama-30 ukuya kwengama-60 emva kolawulo kwaye zihlala malunga neeyure ezi-4.
Indlela yokuthatha
Umthamo uxhomekeke kwifom yedosi esetyenzisiweyo:
1. Ipilisi elula
Ithamo elicetyiswayo kubantu abadala nakwishumi elivisayo ngaphezulu kweminyaka eli-15 li-1 ukuya kwezi-2 iipilisi ze-500 mg okanye ithebhulethi enye ye-1000 mg ukuya kumaxesha ama-4 ngosuku. Eli yeza akufuneki ukuhlafunwa.
2. Ithebhulethi esebenzayo
Ithebhulethi kufuneka inyibilike kwisiqingatha seglasi yamanzi kwaye kufuneka iselwe kwangoko emva kokuphela kwayo. Idosi ekhuthazwayo yithebhulethi enye ukuya kuthi ga kuma-4 ngemini.
3. Isisombululo somlomo 500 mg / mL
Idosi ekucetyiswa ukuba yenziwe ngabantu abadala nakwishumi elivisayo ngaphezulu kweminyaka eli-15 ngama-20 ukuya kuma-40 amathontsi kwidosi enye okanye ukuya kuthi ga kwiitoni ezingama-40, amaxesha amane ngemini. Kubantwana, idosi kufuneka iguqulelwe kubungakanani kunye nobudala, ngokwale theyibhile ilandelayo:
| Ubunzima (iminyaka yobudala) | Ithamo | Amaconsi |
| I-5 ukuya kwi-8 kg (iinyanga ezi-3 ukuya kwezi-11) | Idosi enye Idosi ephezulu | Amaconsi ama-2 ukuya ku-5 20 (idosi ezi-4 x 5 amathontsi) |
| I-9 ukuya kwi-15 kg (1 ukuya kwi-3 iminyaka) | Idosi enye Idosi ephezulu | Amathontsi ayi-3 ukuya ku-10 I-40 (idosi ezi-4 x i-10 yehla) |
| I-16 ukuya kwi-23 kg (iminyaka emi-4 ukuya kwe-6) | Idosi enye Idosi ephezulu | 5 ukuya kwi-15 yehla I-60 (idosi ezi-4 x i-15 yehla) |
| I-24 ukuya kwi-30 kg (iminyaka esi-7 ukuya kweli-9) | Idosi enye Idosi ephezulu | Amathontsi ayi-8 ukuya kuma-20 I-80 (idosi ezi-4 x ama-20 amathontsi) |
| I-31 ukuya kwi-45 kg (iminyaka eli-10 ukuya kweli-12) | Idosi enye Idosi ephezulu | Amathontsi ayi-10 ukuya kuma-30 I-120 (idosi ezi-4 x 30 amathontsi) |
| I-46 ukuya kwi-53 kg (iminyaka eli-13 ukuya kweli-14) | Idosi enye Idosi ephezulu | 15 ukuya kuma-35 amathontsi 140 (4 ithatha x 35 amathontsi) |
Abantwana abangaphantsi kweenyanga ezintathu ubudala okanye ubunzima obungaphantsi kwe-5 kg akufuneki baphathwe ngeDipyrone.
4. Isisombululo somlomo 50 mg / mL
Ithamo elicetyiswayo kubantu abadala nakwishumi elivisayo ngaphezulu kweminyaka eli-15 li-10 ukuya kuma-20 ml, kwidosi enye okanye ukuya kuthi ga kwi-20 mL, amaxesha amane ngemini. Kubantwana, idosi kufuneka ilawulwe ngokobunzima kunye nobudala, ngokwetheyibhile engezantsi:
| Ubunzima (iminyaka yobudala) | Ithamo | Isisombululo somlomo (kwi-mL) |
I-5 ukuya kwi-8 kg (iinyanga ezi-3 ukuya kwezi-11) | Idosi enye Idosi ephezulu | 1.25 ukuya ku-2.5 I-10 (iidosi ezi-4 x 2.5 mL) |
| I-9 ukuya kwi-15 kg (1 ukuya kwi-3 iminyaka) | Idosi enye Idosi ephezulu | 2.5 ukuya ku-5 I-20 (iidosi ezi-4 x 5 ml) |
| I-16 ukuya kwi-23 kg (iminyaka emi-4 ukuya kwe-6) | Idosi enye Idosi ephezulu | 3.75 ukuya ku-7.5 I-30 (iidosi ezi-4 x 7.5 mL) |
| I-24 ukuya kwi-30 kg (iminyaka esi-7 ukuya kweli-9) | Idosi enye Idosi ephezulu | 5 ukuya ku-10 40 (4 x 10 ml iziseko) |
| I-31 ukuya kwi-45 kg (iminyaka eli-10 ukuya kweli-12) | Idosi enye Idosi ephezulu | 7.5 ukuya ku-15 60 (iziseko ezi-4 x 15 ml) |
| I-46 ukuya kwi-53 kg (iminyaka eli-13 ukuya kweli-14) | Idosi enye Idosi ephezulu | 8.75 ukuya ku-17.5 70 (iziseko ezi-4 x 17.5 ml) |
Abantwana abangaphantsi kweenyanga ezintathu ubudala okanye ubunzima obungaphantsi kwe-5 kg akufuneki baphathwe ngeDipyrone.
5. Ukuxhasa
Izinto ezongezwayo ekufuneka zisetyenzisiwe zisetyenzisiwe, ngolu hlobo lulandelayo:
- Soloko ugcina ukuphakheja kwe-suppository kwindawo epholileyo;
- Ukuba i-suppositories ithanjiswe bubushushu, ukupakishwa kwe-aluminium kufuneka kugxunyekwe imizuzwana embalwa emanzini omkhenkce ukuyibuyisela kulungelelwaniso lwayo lwantlandlolo;
- Ukulandela ukugqobhoza kwipakethi yealuminium, kufuneka kugcinwe kuphela indawo yokugcina izinto esetyenziswayo;
- Ngaphambi kokufaka i-suppository, kufuneka uhlambe izandla zakho kwaye, ukuba kunokwenzeka, zibulale iintsholongwane ngotywala;
- Ngomnwe wakho wesithupha kunye nesalathiso, hambisa iimpundu zakho ngaphandle kwaye ufake i-suppository kwi-orifice ye-anal uze ucofe ngobunono impundu enye ngokuchasene nenye imizuzwana embalwa ukukhusela i-suppository ukuba ingabuyi.
Idosi ekucetyiswa ukuba suppository 1, amaxesha 4 ngosuku. Ukuba isiphumo sedosi enye asonelanga okanye emva kokuba isiphumo se-analgesic siphumile, idosi inokuphindwa ngokubhekisele kwi-posology kunye nedosi ephezulu yemihla ngemihla.
6. Isisombululo ngenaliti
I-dipyrone ejoyiweyo inokulawulwa ngaphakathi okanye nge-intramuscularly, xa umntu elele phantsi phantsi kweliso lonyango. Ukongeza, ulawulo lwe-intravenous kufuneka lucothe kakhulu, ngeqondo lokumiliselwa elingagqithiyo kwi-500 mg yedipyrone ngomzuzu, ukuthintela iimpendulo ze-hypotensive.
Idosi ekucetyiswa ukuba yenziwe ngabantu abadala nakwishumi elivisayo ngaphezulu kweminyaka eli-15 yi-2 ukuya kwi-5 ml ngethamo elinye, ukuya kuthi ga kwi-10 mL yemihla ngemihla. Kubantwana neentsana, idosi ekhuthazwayo ixhomekeke kubunzima, njengoko kubonisiwe kule theyibhile ilandelayo:
| Ubunzima | Umthamo (kwi-mL) |
| Iintsana ukusuka kwi-5 ukuya kwi-8 kg | I-0.1 - 0.2 ml |
| Abantwana ukusuka kwi-9 ukuya kwi-15 kg | 0.2 - 0.5 ml |
| Abantwana ukusuka kwi-16 ukuya kwi-23 kg | 0.3 - 0.8 mL |
| Abantwana ukusuka kwi-24 ukuya kwi-30 kg | 0.4 - 1.0 ml |
| Abantwana ukusuka kwi-31 ukuya kwi-45 kg | 0.5 - 1.5 ml |
| Abantwana ukusuka kwi-46 ukuya kuma-53 kg | 0.8 - 1.8 ml |
Ukuba ulawulo lwabazali be-dipyrone luthathelwa ingqalelo kwiintsana ukusuka kwi-5 ukuya kwi-8 kg, kufuneka kusetyenziswe kuphela indlela ye-intramuscular.
Ingaba isebenza kanjani
I-Dipyrone yinto ene-analgesic, antipyretic kunye ne-spasmolytic effects. I-Dipyrone yiprodrug, oko kuthetha ukuba iyasebenza kuphela emva kokungeniswa kunye ne-metabolism.
Olunye uphononongo lubonisa ukuba i-metabolites esebenzayo ye-dipyrone isenzo ngokuthintela ii-enzymes cyclooxygenase (COX-1, COX-2 kunye ne-COX-3), kuthintela ukuhlanganiswa kweeprostaglandin, ngokukhethekileyo kwinkqubo ye-nervous central kunye ne-desensitizing i-receptors ye-peripheral pain, ebandakanya Umsebenzi nge-nitric oxide-cGMP kwi-receptor yeentlungu.
Iziphumo ebezingalindelekanga ezinokwenzeka
Iziphumo ebezingalindelekanga zeDipyrone zibandakanya iinyosi, uxinzelelo lwegazi olusezantsi, ukuphazamiseka kwezintso kunye nokuchama, ukuphazamiseka kwemithambo yegazi kunye nokuphazamiseka okunzima.
Ngubani ongafanele asebenzise
I-Dipyrone iyaphikiswa xa ukhulelwe, ukuncancisa kunye nabantu abane-allergies kwi-sodium dipyrone okanye naziphi na izinto zefomula, i-asthma, i-porphyria yesibindi kunye ne-glucose-6-phosphate dehydrogenase.
Izigulana ezenze i-bronchospasm okanye ezinye iimpendulo ze-anaphylactic nge-analgesics, ezinje nge-salicylates, i-paracetamol, i-diclofenac, ibuprofen, indomethacin kunye ne-naproxen, akufuneki zithathe i-sodium dipyrone.
Kwiimeko zomkhuhlane, bubushushu obunjani ekufuneka buthathwe?
Umkhuhlane luphawu olufuna ukulawulwa kuphela xa lubangela ukungonwabi okanye lonakalisa imeko yomntu ngokubanzi. Ke, i-dipyrone kufuneka isetyenziswe kuphela kwezi meko okanye ukuba ibonisiwe ngugqirha.
Izithuba Ezitsha
Inalxone Inaliti
