Voriconazole

Umxholo

• Iimpawu zeVoriconazole
• Ixabiso leVoriconazole
• Iziphumo ebezingalindelekanga zeVoriconazole
• Ukungqinelana neVoriconazole
• Uyisebenzisa kanjani iVoriconazole

IVoriconazole sisixhobo esisebenzayo kumayeza okubola abizwa ngokuthengisa njengeVfend.

Eli yeza lokusetyenziswa ngomlomo litofile kwaye libonakalisiwe kunyango lwe-aspergillosis, kuba isenzo sayo siphazamisa i-ergosterol, into ebalulekileyo yokugcina ingqibelelo yenwebu yeseli yfungal, ephela ibuthathaka kwaye isuswe emzimbeni.

Iimpawu zeVoriconazole

Aspergillosis; usulelo olubi lwefungal.

Ixabiso leVoriconazole

I-200 mg bunch yeVoriconazole equkethe i-ampoule yexabiso elimalunga ne-1,200 reais, i-200 mg ibhokisi yomlomo yokusebenzisa equlathe iipilisi ezili-14 ezibiza malunga nama-5,000 reais.

Iziphumo ebezingalindelekanga zeVoriconazole

Ukwandisa i-creatinine; ukuphazamiseka okubonakalayo (ukutshintsha okanye ukwanda kwembono ebonakalayo; umbono ongenantsingiselo, utshintsho kumbala wombono, ubuntununtunu ekukhanyeni).

Ukungqinelana neVoriconazole

Umngcipheko wokukhulelwa D; abafazi abancancisayo; hypersensitivity kwimveliso okanye ezinye i-azoles; ukunyamezelana kwegalactose; ukuswela i-lactase.

Uyisebenzisa kanjani iVoriconazole

Ukusetyenziswa okungafunekiyo

Ukufakwa ngaphakathi.

Abantu abadala

• Idosi yokuhlaselwa: I-6 mg ngekg yesisindo somzimba rhoqo kwiiyure ezili-12 ngeedosi ezi-2, kulandele idosi yesondlo ye-4 mg ngekg yesisindo somzimba rhoqo kwiiyure ezili-12. Ngokukhawuleza (ukuba isigulana siyanyamezela), tshintshela kumlomo. Ukuba isigulana asinyamezeli, nciphisa ukuya kwi-3 mg ngeekhilogram ubunzima bomzimba rhoqo nge-12 h.
• Abadala: idosi efanayo neyabantu abadala.
• Izigulana ezinesifo sokusilela kwesibindi: sika idosi yesondlo kwisiqingatha.
• Izigulana ezinesibindi esomeleleyo: Sebenzisa kuphela ukuba izibonelelo zingaphezulu komngcipheko.
• Abantwana abaneminyaka eli-12 ubudala: ukhuseleko nokusebenza okungaqinisekiswanga.

Ukusetyenziswa komlomo

Abantu abadala

• Ukulinganisa ngaphezu kwama-40 kg: Idosi yesondlo yi-200 mg qho kwiiyure ezili-12, ukuba impendulo ayonelanga, idosi inokunyuswa iye kwi-300 mg qho kwiiyure ezili-12 (ukuba isigulana asinyamezeli, yenza ukunyuswa kwama-50 mg rhoqo ngeyure ezili-12).
• Ubunzima obungaphantsi kwama-40 kg: Idosi yesondlo ye-100 mg qho kwiiyure ezili-12, ukuba impendulo ayonelanga, idosi inokunyuswa iye kwi-150 mg ngeeyure eziyi-12 (ukuba isigulana asinyamezeli, sinciphise siye kwi-100 mg qho kwiiyure ezili-12).
• Izigulana ezinesibindi: ukunciphisa idosi kunokuba yimfuneko.
• Abadala: iidosi ezifanayo njengabantu abadala.
• Abantwana abaneminyaka eli-12 ubudala: ukhuseleko nokusebenza okungaqinisekiswanga.