Ngaba isifo sikaMachado Joseph siyanyangeka?

Umxholo

• Unyango lwenziwa njani
• Zenziwa njani iiseshoni ze-physiotherapy
• Ngubani onokuba nesi sifo
• Uxilongo lwenziwa njani

Isifo seMachado-Joseph sisifo esinqabileyo semfuza esibangela ukonakala okungapheliyo kwenkqubo yemithambo-luvo, ebangela ukuphulukana nolawulo lwezihlunu kunye nokulungelelanisa, ngakumbi ezingalweni nasemilenzeni.

Ngokubanzi, esi sifo sivela emva kweminyaka engama-30, sihlala ngokuqhubekayo, sichaphazela izihlunu zemilenze neengalo kwaye siqhubeka ngokuhamba kwexesha ukuya kwimisipha ejongene nokuthetha, ukuginya nokuhamba kwamehlo.

Isifo sikaMachado-Joseph asinakuphiliswa, kodwa sinokulawulwa ngokusetyenziswa kwamayeza kunye neeseshoni ze-physiotherapy, ezinceda ukunciphisa iimpawu kunye nokuvumela ukusebenza ngokuzimeleyo kwemisebenzi yemihla ngemihla.

Unyango lwenziwa njani

Unyango lwezifo zikaMachado-Joseph kufuneka zikhokelwe yi-neurologist kwaye zihlala zijolise ekunciphiseni ukusikelwa umda okuvela ngokuqhubela phambili kwesi sifo.

Ke, unyango lunokwenziwa nge:

• Ukufumana amayeza kaParkinson, njenge-Levodopa: ukunceda ukunciphisa ukuqina kwentshukumo kunye neenyikima;
• Ukusetyenziswa kwamayeza antispasmodicNjengoko Baclofeno: kuthintela imbonakalo spasms kwezihlunu, ukuphucula intshukumo;
• Ukusetyenziswa kweiglasi okanye iilensi zokulungisa: ukunciphisa ubunzima ekuboneni nasekubonakaleni kokubona kabini;
• Utshintsho ekondleni: ukunyanga iingxaki ezinxulumene nobunzima bokuginya, ngotshintsho kwindlela yokutya, umzekelo.

Ukongeza, ugqirha unokucebisa ukuba enze iiseshoni zonyango lomzimba ukunceda isigulana ukuba boyise ukusikelwa umda komzimba kunye nokukhokelela kubomi obuzimeleyo ekwenzeni imisebenzi yemihla ngemihla.

Zenziwa njani iiseshoni ze-physiotherapy

Unyango lomzimba lwesifo sikaMachado-Joseph lwenziwa ngokuziqhelanisa rhoqo ukunceda isigulana siphumelele kwimida ebangelwa sesi sifo. Ke ngoko, ngexesha leeseshoni ze-physiotherapy, imisebenzi eyahlukeneyo inokusetyenziswa, ukusuka ekwenzeni umthambo ukugcina ukuphakama kwamalungu, ukufunda ukusebenzisa iintonga okanye izitulo ezinamavili, umzekelo.

Ukongeza, i-physiotherapy inokubandakanya ukuginya unyango lokuvuselela olucetyiswayo kwaye lubalulekile kuzo zonke izigulana ezinobunzima bokuginya ukutya, okunxulumene nomonakalo wemithambo-luvo obangelwa sesi sifo.

Ngubani onokuba nesi sifo

Isifo seMachado-Joseph sibangelwa kukutshintsha kwemfuza okukhokelela kwimveliso yeprotein, eyaziwa ngokuba yiAtaxin-3, eqokelela kwiiseli zobuchopho ezibangela ukukhula kwezilonda eziqhubekayo kunye nokubonakala kweempawu.

Njengengxaki yemfuza, isifo sikaMachado-Joseph siqhelekile kubantu abaliqela kusapho olunye, benethuba le-50% lokudlula ukusuka kubazali baye kubantwana. Xa oku kusenzeka, abantwana banokuphuhlisa iimpawu zokuqala zesifo ngaphambi kwabazali babo.

Uxilongo lwenziwa njani

Kwiimeko ezininzi, isifo sikaMachado-Joseph sibonwa ngokujonga iimpawu ze-neurologist kunye nokuphanda ngembali yosapho yesi sifo.

Ukongeza, kukho uvavanyo lwegazi, olwaziwa njenge-SCA3, ekuvumela ukuba uchonge utshintsho kwimfuza olubangela esi sifo. Ngale ndlela, xa unomntu kusapho onesi sifo, kwaye kuvavanywa, kunokwenzeka ukuba ufumanise ukuba ngowuphi umngcipheko wokuba nesi sifo.