Yintoni isifo seGestational Trophoblastic

Umxholo

• Iindidi zesifo sokukhulelwa kwetrophoblastic
• Ziintoni iimpawu
• Izizathu ezinokubangela
• Yintoni isifo
• Unyango lwenziwa njani

Isifo se-Gestational trophoblastic, esikwabizwa ngokuba yi-hydatidiform mole, yinto enqabileyo, ebonakaliswa kukukhula okungaqhelekanga kwe-trophoblast, iiseli ezikhula kwi-placenta kwaye ezinokubangela iimpawu ezinje ngeentlungu zesisu, ukopha kwilungu lobufazi, isicaphucaphu kunye nokugabha.

Esi sifo sinokwahlulwa sibe yinto epheleleyo okanye eyinxalenye ye-hydatidiform mole, ezizezona zixhaphakileyo, i-mole engenayo, i-choriocarcinoma kunye ne-trophoblastic tumor.

Ngokubanzi, unyango luquka utyando lokususa i-placenta kunye nezicubu kwi-endometrium, ekufuneka yenziwe ngokukhawuleza, kuba esi sifo singakhokelela kubunzima, njengokuphuhliswa komhlaza.

Iindidi zesifo sokukhulelwa kwetrophoblastic

Isifo se-Gestational trophoblastic sehlukaniswe:

• Gcwalisa i-hydatidiform mole, eyona nto ixhaphakileyo kwaye isiphumo sokudityaniswa kweqanda elingenanto, elingenayo i-nucleus ene-DNA, nge-1 okanye kwi-2 sperm, eneempembelelo zokuphindaphindeka kwee-chromosomes zooyise kunye nokungabikho kwethishu yokubumba, ekhokelela ukulahleka kwezicubu zomntwana, umbungu kunye nokwanda kwezicubu ze-trophoblastic;
• Inxalenye ye-hydatidiform mole, apho iqanda eliqhelekileyo lichunyiswa sisidoda esi-2, kunye nokwakheka kwethishu engaqhelekanga yomntwana kunye nokuqhomfa okuzenzekelayo okuzenzekelayo;
• Intwasahlobo ehlaselayo, enqabileyo kunaleyo yangaphambili kwaye apho kwenzeka khona uhlaselo lwe-myometrium, olunokubangela ukubhoboka kwesibeleko kunye nokukhokelela ekopha kakhulu;
• I-Choriocarcinoma, esisilonda esihlaselayo kunye nesimetastatic, esenziwe ziiseli ezinobungozi be-trophoblastic. Uninzi lwezi tumors lukhula emva kwentwasahlobo ye-hydatidiform;
• I-trophoblastic tumor yendawo ye-placental, esisifo esinqabileyo, esineeseli eziphakathi ze-trophoblastic cell, eziqhubeka emva kokuphela kokukhulelwa, kwaye zinokuhlasela izicubu ezikufutshane okanye zenze imastastases.

Ziintoni iimpawu

Ezona mpawu zixhaphakileyo ezinokuthi zenzeke kubantu abanesifo se-trophoblastic sisifo esibomvu esibomvu esivela kwilungu lobufazi ngexesha lokuqala kwenyanga yokuqala, isicaphucaphu kunye nokugabha, iintlungu zesisu, ukugxothwa kwamaqhakuva kwilungu lobufazi, ukukhula ngokukhawuleza kwesibeleko, ukunyuka koxinzelelo lwegazi, i-anemia, hyperthyroidism kunye ne-pre eclampsia.

Izizathu ezinokubangela

Esi sifo siphumela ekuchumiseni okungaqhelekanga kweqanda elingenanto, ngesidoda esinye okanye ezibini, okanye kwiqanda eliqhelekileyo ngesidoda esi-2, ukuphindaphinda kwezi chromosomes kunika iseli engaqhelekanga, eza kuphinda-phinda.

Ngokubanzi, kukho umngcipheko omkhulu wokukhula kwesifo se-trophoblastic kubafazi abangaphantsi kweminyaka engama-20 okanye ngaphezulu kwama-35 okanye kwabo sele benesi sifo.

Yintoni isifo

Ngokubanzi, ukuxilongwa kubandakanya ukwenza uvavanyo lwegazi ukubona i-hCG hormone kunye ne-ultrasound, apho kunokwenzeka khona ukugcina ubukho be-cysts kunye nokungabikho okanye ukungahambi kakuhle kwizicubu zomntwana kunye ne-amniotic fluid.

Unyango lwenziwa njani

Ukukhulelwa okungafunekiyo akunakuphumelela kwaye ke kubalulekile ukuba ususwe i-placenta ukukhusela iingxaki ezivela. Ngale nto, ugqirha unokwenza unyango, olo luqhaqho apho izicubu zesibeleko zisuswe khona, kwigumbi lokusebenza, emva kolawulo lwe-anesthesia.

Ngamanye amaxesha ugqirha unokucebisa ngokususa isibeleko, ngakumbi ukuba kukho umngcipheko wokuba nomhlaza, ukuba umntu lowo akafuni ukuba nabantwana ngakumbi.

Emva konyango, umntu kufuneka akhatshwe ngugqirha kwaye enze iimvavanyo rhoqo, isithuba esingangonyaka, ukujonga ukuba zonke izicubu zisuswe ngokufanelekileyo na kwaye akukho bungozi bokuba neengxaki.

Kusenokuba yimfuneko ukwenza ichemotherapy kwesi sifo siqhubekayo.