Iziphumo zeCholesterol ephezulu kuMzimba

Umxholo

• Iinkqubo zentliziyo kunye nokujikeleza kwegazi
• Inkqubo ye-Endocrine
• Inkqubo yovalo
• Inkqubo yokwetyisa

Ikholesterol yinto egalelwe yetyu efumaneka kwigazi lakho nakwiiseli zakho. Isibindi sakho senza uninzi lwecholesterol emzimbeni wakho. Ezinye zivela kukutya okutyayo. Ikholesterol ihamba egazini lakho ixutywe kwiipakethi ezibizwa ngokuba ziipopoproteins.

Ikholesterol iza ngeendlela ezimbini:

Ubuninzi be-lipoprotein (LDL) luhlobo olubi lwe-cholesterol. I-cholesterol ye-LDL inokwakha kwimithambo yakho kwaye yenze amanqatha, iidipozithi ze-waxy ezibizwa ngokuba ngamacwecwe.

Ubuninzi be-lipoprotein (HDL) luhlobo “olulungileyo,” olusempilweni lwecholesterol. Ihambisa i-cholesterol engaphezulu kwemithambo yakho iye kwisibindi sakho, esisusa emzimbeni wakho.

I-cholesterol ngokwayo ayibi. Umzimba wakho ufuna icholesterol ethile ukuze wenze iihomoni, ivithamin D, kunye neencindi zokwetyisa. Ikholesterol ikwanceda amalungu akho asebenze ngokufanelekileyo.

Nangona kunjalo ukuba ne-cholesterol eninzi ye-LDL kunokuba yingxaki. I-cholesterol ephezulu ye-LDL ekuhambeni kwexesha inokonakalisa imithambo yakho yegazi, igalelo kwisifo sentliziyo, kwaye yonyuse umngcipheko wokuhlaselwa sisifo. Ukufumana i-cholesterol yakho ihlolwe rhoqo kutyelelo logqirha kunye nokunciphisa ingozi yesifo sentliziyo ngokutya, ukuzilolonga, utshintsho kwindlela yokuphila, kunye nonyango kunokunceda ukunciphisa iingxaki ezinxulumene nesifo sentliziyo kunye nokuphucula umgangatho wobomi.

Iinkqubo zentliziyo kunye nokujikeleza kwegazi

Xa une-cholesterol eninzi ye-LDL emzimbeni wakho inokwakha kwimithambo yakho, iwavale kwaye ibenze bhetyebhetye. Ukuqina kwemithambo kuthiwa yi-atherosclerosis. Igazi alihambi kakuhle ngemithambo eqinileyo, ke intliziyo yakho kufuneka isebenze nzima ukutyhala igazi ngalo. Ixesha elingaphezulu, njengoko i-plaque isakha kwimithambo yakho, ungaphuhlisa isifo sentliziyo.

Ukwakhiwa kweplaque kwimithambo yegazi kunokuphazamisa ukuhamba kwegazi eline-oksijini kwintliziyo yakho. Oku kunokubangela iintlungu zesifuba ekuthiwa yi-angina. U-Angina akayonto yokuhlaselwa sisifo sentliziyo, kodwa kukuphazamiseka okwexeshana kokuhamba kwegazi. Sisilumkiso sokuba usemngciphekweni wokuhlaselwa sisifo sentliziyo. Iqhekeza leplanga ekugqibeleni linokuqhekeka kwaye lenze iqokobhe okanye umthambo unokuqhubeka nokuxinana okunokuthintela ngokupheleleyo ukuhamba kwegazi kuye entliziyweni yakho, okukhokelela kwisifo sentliziyo. Ukuba le nkqubo yenzeka kwimithambo yegazi eya kwingqondo okanye ngaphakathi kwengqondo inokukhokelela kwisifo.

Iplaque inokuthintela ukuhamba kwegazi ukuya kwimithambo ebonelela ngegazi kumathumbu akho, imilenze, kunye neenyawo. Oku kubizwa ngokuba sisifo se-arterial disease (PAD).

Inkqubo ye-Endocrine

Amadlala avelisa umzimba wakho asebenzisa icholesterol ukwenza iihomoni ezifana ne-estrogen, testosterone, kunye ne-cortisol. IiHormone zinokuba nefuthe kumanqanaba omzimba wakho we-cholesterol. Uphando lubonakalisile ukuba njengoko amanqanaba e-estrogen enyuka ngexesha lokuya exesheni komfazi, amanqanaba e-cholesterol ye-HDL nawo ayenyuka, kunye namazinga e-cholesterol ye-LDL ayehla. Esi isenokuba sesinye sezizathu zokuba ingozi yomfazi kwisifo sentliziyo inyuke emva kokuyeka ukuya exesheni, xa amanqanaba e-estrogen ehla.

Ukuveliswa kwemveliso yehomoni ye-thyroid (hypothyroidism) kukhokelela ekunyukeni kwe-cholesterol iyonke kunye ne-LDL. Ukugqithisa kwehomoni ye-thyroid (hyperthyroidism) ineempembelelo ezichaseneyo. Unyango lwe-Androgen lokuthintela unyango, olucutha amanqanaba eehomoni zesilisa ukumisa ukukhula komhlaza wedlala lesinyi, lunokunyusa amanqanaba e-cholesterol ye-LDL. Ukusilela kokukhula kwehomoni nako kunokunyusa amanqanaba e-cholesterol ye-LDL.

Inkqubo yovalo

Ikholesterol yinto ebalulekileyo kwingqondo yomntu. Ngapha koko, ingqondo iqulethe malunga neepesenti ezingama-25 zokufumana konke komzimba wecholesterol. La mafutha abalulekile ekukhuleni nasekukhuseleni iiseli zemithambo-luvo, ezenza ukuba ingqondo inxibelelane nomzimba uphela.

Ngelixa ufuna icholesterol ukuze ingqondo yakho isebenze ngokugqibeleleyo, ubuninzi bayo bunokonakalisa. Ukugqitha kwecholesterol kwimithambo kunokukhokelela kwimivumbo - ukuphazamiseka kokuhamba kwegazi okunokonakalisa iinxalenye zobuchopho, okukhokelela ekuphulukaneni nenkumbulo, ukuhamba, ubunzima ngokuginya kunye nokuthetha kunye neminye imisebenzi.

I-cholesterol ephezulu yegazi ngokwayo iye yanyanzeliswa ukulahleka kwememori kunye nokusebenza kwengqondo. Ukuba ne-cholesterol ephezulu yegazi kunokukhawulezisa ukwenziwa kwamacwecwe e-beta-amyloid, iiproteni ezinamathelayo ezonakalisa ingqondo kubantu abanesifo se-Alzheimer's.

Inkqubo yokwetyisa

Kwinkqubo yokwetyisa, i-cholesterol ibalulekile kwimveliso yenyongo-into enceda umzimba wakho ukuba uqhekeze ukutya kunye nokufunxa izondlo emathunjini akho. Kodwa ukuba une-cholesterol eninzi kakhulu kwi-bile yakho, iifom ezigqithileyo zibe ziikristali kwaye emva koko amatye anzima kwi-gallbladder yakho. Iigallstones zinokuba buhlungu kakhulu.

Ukugcina iso kwinqanaba le-cholesterol yakho kunye novavanyo lwegazi olucetyiswayo kunye nokunciphisa umngcipheko wesifo sentliziyo kuya kunceda ukuphucula umgangatho wobomi bakho bonke.