I-Scetamine (Spravato): amayeza amatsha e-intranasal yoxinzelelo

Umxholo

• Yenzelwe ntoni
• Kusetyenziswa kwanjani
• Ngubani ongafanele asebenzise
• Iziphumo ebezingalindelekanga ezinokwenzeka

I-Esthetamine yinto eboniswe kunyango loxinzelelo olunganyangekiyo kolunye unyango, kubantu abadala, ekufuneka isetyenziswe ngokudibeneyo nenye inyango yomlomo.

Eli chiza alikathengiswa eBrazil, kodwa sele livunyiwe yi-FDA ukuba ithengiswe e-United States, phantsi kwegama lezorhwebo iSpravato, ukuze ilawulwe ngaphakathi.

Yenzelwe ntoni

I-Esthetamine sisiyobisi ekufuneka senziwe ngaphakathi, sidityaniswe ne-antidepressant yomlomo, kunyango loxinzelelo olunganyangekiyo kolunye unyango.

Kusetyenziswa kwanjani

Eli yeza kufuneka linikezelwe ngaphakathi, phantsi kweliso lengcali yezempilo, ekufuneka ihlole uxinzelelo lwegazi ngaphambi nasemva kolawulo.

I-Spravato kufuneka ilawulwe kabini ngeveki kwiiveki ezi-4. Idosi yokuqala kufuneka ibe yi-56 mg kwaye elandelayo ibe ngama-56 mg okanye i-84 mg. Emva koko, ukusuka kwi-5 ukuya kwiveki ye-8, idosi ekhuthazwayo yi-56 mg okanye i-84 mg, kanye ngeveki, kwaye ukusuka kwiveki ye-9, i-56 mg okanye i-84 mg inokuqhutywa kuphela kwiiveki ezimbini, okanye ngokokubona kukagqirha. .

Isixhobo sokutshiza ngeempumlo sikhupha kuphela iidosi ezi-2 zizonke ezingama-28 mg ze-escetamine, ukuze idosi enye ibekwe kwimpumlo nganye. Ke, ukuze ufumane idosi ye-56 mg, kufuneka kusetyenziswe izixhobo ezi-2, kunye nedosi ye-84 mg, izixhobo ezi-3 kufuneka zisetyenziswe, kwaye umntu kufuneka alinde malunga nemizuzu emi-5 phakathi kokusebenzisa isixhobo ngasinye.

Ngubani ongafanele asebenzise

Esi sixhobo sichasene nabantu abane-hypersensitivity kumacandelo efomula, kubantu abane-aneurysm, abane-arteriovenous malformation okanye abanembali yokuphuma kwegazi ngaphakathi.

Iziphumo ebezingalindelekanga ezinokwenzeka

Ezinye zeziphumo ebezingalindelekanga ezinokubakho ngokusetyenziswa kwe-escetamine kukungazibandakanyi, isiyezi, isicaphucaphu, isisu, isiyezi, ukwehla kobuntununtunu kwimimandla ethile yomzimba, unxunguphalo, ukonqena, ukunyuka koxinzelelo lwegazi, ukugabha nokuziva unxilile.